Advanced Science, EarlyView.ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch +4 more
wiley +1 more source
Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development. [PDF]
PLoS GenetAmezquita J +8 more
europepmc +1 more source
Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. [PDF]
Nat Protoc, 2022 Engmann AK +7 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Identification of the growth cone as a probe and driver of neuronal migration in the injured brain. [PDF]
Nat CommunNakajima C +27 more
europepmc +1 more source
Breaking symmetry - cell polarity signaling pathways in growth cone guidance and synapse formation. [PDF]
Curr Opin Neurobiol, 2020 Zou Y.
europepmc +1 more source
Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics
Advanced Science, EarlyView.The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet +8 more
wiley +1 more source
The geometry of photopolymerized topography influences neurite pathfinding by directing growth cone morphology and migration. [PDF]
J Neural EngVecchi JT +3 more
europepmc +1 more source
Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites. [PDF]
Elife, 2020 Liang X +6 more
europepmc +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
Advanced Science, EarlyView.A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source