Results 11 to 20 of about 6,281,711 (333)
Regulation of growth cone motility [PDF]
Cell Motility, 1991 Nerve growth cones are the motile tips of elongating axons and dendrites. The migration and behavior of growth cones are responsible for axonal pathfinding to synaptic targets, and for the branching patterns of dendritic trees. Growth cones are studied at all levels of organization, molecular, cellular, and within intact embryos. Preparations of growth
Paul C. Letourneau, Christopher Cypher
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Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment [PDF]
Cells, 2020 By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
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Model for Coordination of Microtubule and Actin Dynamics in Growth Cone Turning [PDF]
Frontiers in Cellular Neuroscience, 2018 In the developing nervous system, axons are guided to their synaptic targets by motile structures at the axon tip called growth cones, which reorganize their cytoskeleton in order to steer in response to chemotactic cues. Growth cone motility is mediated
Erin M. Craig
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Actin-based growth cone motility and guidance. [PDF]
Mol Cell Neurosci, 2017 Omotade OF, Pollitt SL, Zheng JQ.
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Growth Factors as Axon Guidance Molecules: Lessons From in vitro Studies
Frontiers in Neuroscience, 2021 Growth cones at the tips of extending axons navigate through developing organisms by probing extracellular cues, which guide them through intermediate steps and onto final synaptic target sites.
Massimo M. Onesto +4 more
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Coactosin Promotes F-Actin Protrusion in Growth Cones Under Cofilin-Related Signaling Pathway
Frontiers in Cell and Developmental Biology, 2021 During brain development, axon outgrowth and its subsequent pathfinding are reliant on a highly motile growth cone located at the tip of the axon. Actin polymerization that is regulated by actin-depolymerizing factors homology (ADF-H) domain-containing ...
Xubin Hou +5 more
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Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons
Cells, 2021 Cyclase-associated proteins (CAPs) are evolutionary-conserved actin-binding proteins with crucial functions in regulating actin dynamics, the spatiotemporally controlled assembly and disassembly of actin filaments (F-actin).
Felix Schneider +3 more
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Growth cone dynamics during the migration of an identified commissural growth cone [PDF]
The Journal of Neuroscience, 1993 We have used time-lapse video microscopy to study the behavior of a neuron, Q1, that pioneers the posterior commissure of the embryonic grasshopper. Our goal is to use time-lapse video as a tool to acquire a precise picture of normal development over time, and thereby identify stereotypic activities that might indicate important interactions necessary ...
Paul Z. Myers, Michael J. Bastiani
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Mechanisms of growth cone repulsion [PDF]
F1000 Biology Reports, 2010 Research conducted in the last century suggested that chemoattractants guide cells or their processes to appropriate locations during development. Today, we know that many of the molecules involved in cellular guidance can act as chemorepellents that prevent migration into inappropriate territories. Here, we review some of the early seminal experiments
Judith S. Eisen, Catherine E. Krull
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High-resolution spatiotemporal analysis of single serotonergic axons in an in vitro system
Frontiers in Neuroscience, 2022 Vertebrate brains have a dual structure, composed of (i) axons that can be well-captured with graph-theoretical methods and (ii) axons that form a dense matrix in which neurons with precise connections operate.
Melissa Hingorani +3 more
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