Results 11 to 20 of about 152,389 (315)
Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling +5 more
wiley +1 more source
Volume staging for arteriovenous malformation SRS treatment using VMAT
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Volume staging involves dividing the target volume into smaller parts and treating each part separately. In this study, the feasibility of volume‐staged stereotactic radiosurgery (VS‐SRS) on a linear accelerator using volumetric modulated arc therapy (VMAT) and a frameless patient positioning system is investigated.
Claudia Mendez, Ermias Gete
wiley +1 more source
Coactosin Promotes F-Actin Protrusion in Growth Cones Under Cofilin-Related Signaling Pathway
Frontiers in Cell and Developmental Biology, 2021 During brain development, axon outgrowth and its subsequent pathfinding are reliant on a highly motile growth cone located at the tip of the axon. Actin polymerization that is regulated by actin-depolymerizing factors homology (ADF-H) domain-containing ...
Xubin Hou +5 more
doaj +1 more source
Geometric frustration of hard-disk packings on cones [PDF]
Physical Review E 108, 054608 (2023), 2023 Conical surfaces pose an interesting challenge to crystal growth: a crystal growing on a cone can wrap around and meet itself at different radii. We use a disk-packing algorithm to investigate how this closure constraint can geometrically frustrate the growth of single crystals on cones with small opening angles. By varying the crystal seed orientation
arxiv +1 more source
The dynamics of growth cone morphology [PDF]
BMC Biology, 2015 Normal brain function depends on the development of appropriate patterns of neural connections. A critical role in guiding axons to their targets during neural development is played by neuronal growth cones. These have a complex and rapidly changing morphology; however, a quantitative understanding of this morphology, its dynamics and how these are ...
Goodhill, Geoffrey J. +8 more
openaire +4 more sources
Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons
Cells, 2021 Cyclase-associated proteins (CAPs) are evolutionary-conserved actin-binding proteins with crucial functions in regulating actin dynamics, the spatiotemporally controlled assembly and disassembly of actin filaments (F-actin).
Felix Schneider +3 more
doaj +1 more source
Growth cone dynamics during the migration of an identified commissural growth cone [PDF]
The Journal of Neuroscience, 1993 We have used time-lapse video microscopy to study the behavior of a neuron, Q1, that pioneers the posterior commissure of the embryonic grasshopper. Our goal is to use time-lapse video as a tool to acquire a precise picture of normal development over time, and thereby identify stereotypic activities that might indicate important interactions necessary ...
Bastiani, Michael, Myers, Paul Z.
openaire +3 more sources
Mechanisms of growth cone repulsion [PDF]
F1000 Biology Reports, 2010 Research conducted in the last century suggested that chemoattractants guide cells or their processes to appropriate locations during development. Today, we know that many of the molecules involved in cellular guidance can act as chemorepellents that prevent migration into inappropriate territories. Here, we review some of the early seminal experiments
Judith S. Eisen, Catherine E. Krull
openaire +3 more sources
eLife, 2018 A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal development, a
Nickolai V Vysokov +10 more
doaj +1 more source
High-resolution spatiotemporal analysis of single serotonergic axons in an in vitro system
Frontiers in Neuroscience, 2022 Vertebrate brains have a dual structure, composed of (i) axons that can be well-captured with graph-theoretical methods and (ii) axons that form a dense matrix in which neurons with precise connections operate.
Melissa Hingorani +3 more
doaj +1 more source