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Rapid effects of laminin on the growth cone
Neuron, 1992To gain insight into how laminin promotes neurite growth, high resolution video microscopy was used to determine the rapid effects of laminin on growth cone structure. Sympathetic growth cones in serum-free medium on polylysine substrate displayed extensive motility and protrusive activity and often had large lamellipodia.
R J, Rivas +2 more
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The dance of the growth cones — where to next?
Trends in Neurosciences, 1995Axon guidance in the developing nervous system is accomplished by a remarkable structure, the axon growth cone. This structure navigates, often over long distances, to find and synapse with target cells. Transformation of the growth cone to a terminal arbor establishes functional circuitry.
R V, Stirling, S A, Dunlop
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Science's STKE, 2004
The semaphorin family of guidance cues act predominantly through plexin receptors at the surface of various cell types. The small guanosine triphosphatases (GTPases) Rho and Rac have been implicated as downstream effectors of semaphorin-plexin interactions that modulate the cytoskeleton, but details of how plexins activate these GTPases ...
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The semaphorin family of guidance cues act predominantly through plexin receptors at the surface of various cell types. The small guanosine triphosphatases (GTPases) Rho and Rac have been implicated as downstream effectors of semaphorin-plexin interactions that modulate the cytoskeleton, but details of how plexins activate these GTPases ...
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Can there be growth without growth cones?
Seminars in Neuroscience, 1996Abstract In-vivo imaging of the development of complex retinotectal axon arbors indicates that arbors branches can form and extend in the absence of growth cones. A variety of imaging protocols were used to observe arbor elaboration over a range of time intervals and total observation periods.
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The Synapse and the Growth Cone
1991Abstract Although anatomists by the r 8gos could agree that nerve cells are separate units and interact by contacts, it left many unanswered questions. Two questions in particular aroused great interest. One was the nature of the contacts between neurons made by axons and dendrites.
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Pathfinding by the Growth Cone
1996The growth cone is a specialization of developing and regenerating neurons which samples the environment and is attracted or repelled by the cues it detects. Different growth cones express different surface receptors or exhibit different second messenger responses to a given cue.
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2000
'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
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'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
openaire +1 more source