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Can there be growth without growth cones?
Seminars in Neuroscience, 1996Abstract In-vivo imaging of the development of complex retinotectal axon arbors indicates that arbors branches can form and extend in the absence of growth cones. A variety of imaging protocols were used to observe arbor elaboration over a range of time intervals and total observation periods.
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Pathfinding by the Growth Cone
1996The growth cone is a specialization of developing and regenerating neurons which samples the environment and is attracted or repelled by the cues it detects. Different growth cones express different surface receptors or exhibit different second messenger responses to a given cue.
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Control of microtubule assembly in growth cones
Journal of Cell Science, 1991ABSTRACT Growth cones are transient structures present at the tips of growing axons and dendrites (neurites). They are crucial to neuronal development because of their pathfinding ability and their role in synaptogenesis (reviewed by Dodd and Jessell, 1988). In the last few years it has become apparent that growth cones are also involved
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2000
'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
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'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
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The Synapse and the Growth Cone
1991Abstract Although anatomists by the r 8gos could agree that nerve cells are separate units and interact by contacts, it left many unanswered questions. Two questions in particular aroused great interest. One was the nature of the contacts between neurons made by axons and dendrites.
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