Results 11 to 20 of about 33,389 (300)
Morphology and nanomechanics of sensory neurons growth cones following peripheral nerve injury. [PDF]
PLoS ONE, 2013 A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Marta Martin +7 more
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Actin dynamics in growth cones [PDF]
The Journal of Neuroscience, 1991 The mechanism of actin incorporation and turnover in the nerve growth cone was examined by immunoelectron microscopy and low-light-level video microscopy of cultured neurons injected with biotin-labeled actin or fluorescently labeled actin.
S Okabe, N Hirokawa
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Regulation of chemotropic guidance of nerve growth cones by microRNA
Molecular Brain, 2011 Background The small non-coding microRNAs play an important role in development by regulating protein translation, but their involvement in axon guidance is unknown.
Han Liang +7 more
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Microtubule organization in growth cones
Biochemical Society Transactions, 1991 Neuronal growth cones guide growing axons and dendrites (neurites) through developing embryos by detecting extrinsic guidance cues and transducing the signal into changes in motile behavior.
Gordon-Weeks, P R; id_orcid
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Actin-Binding Proteins in Nerve Cell Growth Cones
Journal of Pharmacological Sciences, 2007 The motility of the growth cone, an intracellular apparatus located at the tip of the axon in developing neurons, is thought to govern axonal path-finding and the construction of neuronal networks.
Ryoki Ishikawa, Kazuhiro Kohama
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Neuron, 1995 This study examines the mechanisms of spontaneous and induced [Ca2+]i spiking in nerve growth cones and the effect of spikes on growth cone migration.
Letourneau, Paul C +2 more
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Growth cone dynamics during the migration of an identified commissural growth cone [PDF]
The Journal of Neuroscience, 1993 We have used time-lapse video microscopy to study the behavior of a neuron, Q1, that pioneers the posterior commissure of the embryonic grasshopper. Our goal is to use time-lapse video as a tool to acquire a precise picture of normal development over time, and thereby identify stereotypic activities that might indicate important interactions necessary ...
P Z, Myers, M J, Bastiani
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Commissural Axon Kinetics and the Role of Netrin in Early Brain Circuitry Development [PDF]
, 2005 As neurons begin to differentiate, they send out processes called axons to initiate the formation of functional nerve connections. A specialized structure at the end of an axon called the growth cone is believed to possess the impressive navigational and
Bak-Maier, Magdalena
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iScience, 2020 Summary: During neurodevelopment, the growth cone deciphers directional information from extracellular guidance cues presented as shallow concentration gradients via signal amplification.
Carmen Chan +8 more
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FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones. [PDF]
PLoS ONE, 2016 Netrin-1 is an essential extracellular chemoattractant that signals through its receptor DCC to guide commissural axon extension in the embryonic spinal cord.
Benjamin Rappaz +4 more
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