Results 21 to 30 of about 28,917 (260)
Actin dynamics in growth cones [PDF]
The Journal of Neuroscience, 1991 The mechanism of actin incorporation and turnover in the nerve growth cone was examined by immunoelectron microscopy and low-light-level video microscopy of cultured neurons injected with biotin-labeled actin or fluorescently labeled actin. We first determined the sites of actin incorporation into the cytoskeleton of growth cones by immunoelectron ...
S, Okabe, N, Hirokawa
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Morphology and nanomechanics of sensory neurons growth cones following peripheral nerve injury. [PDF]
PLoS ONE, 2013 A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Marta Martin +7 more
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Turkish Journal of Forestry, 2021 In this study, cone production, altitude and growth characteristics (height, diameter at breast height and crown diameter) were related, and also some genetics parameters were estimated.
Durmuş Çetinkaya, Mahmut Çerçioğlu
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The dynamics of growth cone morphology [PDF]
BMC Biology, 2015 Normal brain function depends on the development of appropriate patterns of neural connections. A critical role in guiding axons to their targets during neural development is played by neuronal growth cones. These have a complex and rapidly changing morphology; however, a quantitative understanding of this morphology, its dynamics and how these are ...
Goodhill, Geoffrey J. +8 more
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Regulation of chemotropic guidance of nerve growth cones by microRNA
Molecular Brain, 2011 Background The small non-coding microRNAs play an important role in development by regulating protein translation, but their involvement in axon guidance is unknown.
Han Liang +7 more
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Neuronal Growth Cone Size-Dependent and -Independent Parameters of Microtubule Polymerization
Frontiers in Cellular Neuroscience, 2018 Migration and pathfinding of neuronal growth cones during neurite extension is critically dependent on dynamic microtubules. In this study we sought to determine, which aspects of microtubule polymerization relate to growth cone morphology and migratory ...
Alexa Kiss +4 more
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Mechanisms of growth cone repulsion [PDF]
F1000 Biology Reports, 2010 Research conducted in the last century suggested that chemoattractants guide cells or their processes to appropriate locations during development. Today, we know that many of the molecules involved in cellular guidance can act as chemorepellents that prevent migration into inappropriate territories. Here, we review some of the early seminal experiments
Krull, Catherine E, Eisen, Judith S
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Isolation of Growth Cones from Mouse Brain
Bio-Protocol, 2013 Growth cones are motile structures at the tips of growing neurites, which play an essential role in regulation of growth and navigation of growing axons and dendrites of neurons in the developing nervous system.
Iryna Leshchyns’ka, Vladimir Sytnyk
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Live-cell imaging of PVD dendritic growth cone in post-embryonic C. elegans
STAR Protocols, 2021 Summary: Live-cell imaging analysis provides tremendous information for the study of cellular events such as growth cone migration in neuronal development.
Chun-Hao Chen, Chun-Liang Pan
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Translational regulation in growth cones [PDF]
Current Opinion in Genetics & Development, 2011 Axonal growth cones (GCs) steer in response to extrinsic cues using mechanisms that include local protein synthesis. This adaptive form of gene regulation occurs with spatial precision and depends on subcellular mRNA localisation. Recent genome-wide studies have shown unexpectedly complex and dynamically changing mRNA repertoires in growing axons and ...
Hosung, Jung +2 more
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