Results 31 to 40 of about 66,472 (220)
Energy deprivation and guanosine 5'-diphosphate 3'-diphosphate synthesis in cyanobacteria [PDF]
Journal of Bacteriology, 1982 A reduction in the incident light intensity has been used to elicit guanosine 5'-diphosphate 3'-diphosphate accumulation in cyanobacteria. Inhibitors of photophosphorylation, 2,4-dinitrophenol, and carbonyl cyanide-m-chlorophenyl hydrazone elicited accumulation in three species of cyanobacteria when they were grown on dinitrogen or nitrate, but not in ...
J A, Akinyanju, R J, Smith
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Journal of Lipid Research, 1975 A study was conducted to determine whether retinyl phosphate would act as substrate for the enzymatic synthesis of mannosyl retinyl phosphate. Retinyl phosphate, prepared chemically, supported the growth of vitamin A-deficient rats at the same rate as ...
G.C. Rosso +3 more
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Journal of International Medical Research, 2021 ARHGEF9 encodes collybistin, a brain-specific guanosine diphosphate-guanosine-5′-triphosphate exchange factor that plays an important role in clustering of gephyrin and γ-aminobutyric acid type A receptors in the postsynaptic membrane.
Tong Qiu, Qian Dai, Qiu Wang
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Guanosine 5‘-diphosphate-3‘-diphosphate inhibition of adenylosuccinate synthetase.
Journal of Biological Chemistry, 1979 The mechanism of ppGpp inhibition of adenylosuccinate synthetase (EC 6.3.4.4) was examined. Initial rate kinetic studies demonstrate the ppGpp inhibition is competitive with respect to GTP and noncompetitive with respect to L-aspartate and IMP. This is in contrast to an earlier report (Gallant, J., Irr, J., and Cashel, M. (1971) J. Biol. Chem.
M M, Stayton, H J, Fromm
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Guanosine 5'-diphosphate 3'-diphosphate (ppGpp), guanosine 5'-diphosphate 3'-monophosphate (ppGp) and antibiotic production in Streptomyces clavuligerus [PDF]
Microbiology, 1996 Streptomyces clavuligerus produced cephamycin C under all nutrient limitations investigated in batch culture, whilst clavulanic acid was produced under phosphate and carbon limitations. Guanosine 5′-diphosphate 3′-diphosphate (ppGpp) was produced at very low levels in all fermentations, prior to the detection of cephamycin C in the fermentation broth ...
C. Jones, A. Thompson, R. England
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Rho GTPases as Key Molecular Players within Intestinal Mucosa and GI Diseases
Cells, 2021 Rho proteins operate as key regulators of the cytoskeleton, cell morphology and trafficking. Acting as molecular switches, the function of Rho GTPases is determined by guanosine triphosphate (GTP)/guanosine diphosphate (GDP) exchange and their lipidation
Rashmita Pradhan +4 more
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Synthesis of Guanosine 5'-Diphosphate.
Chemical and Pharmaceutical Bulletin, 1959 Guanosine 5'-diphosphate was synthesized from guanosine 5'-monophosphate by the reaction of benzyl hydrogen phosphoramidate, followed by the catalytic hydrogenolysis, in a yield of 38%. The effect of water in the reaction media and correlation of the yield with the amount of reagents are discussed.
Ueda, Tohru, Ohtsuka, Eiko
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The role of free nucleotides in heart failure
Кардиоваскулярная терапия и профилактикаAim. To assess the potential of studying the plasma level of free nucleotides as additional biomarkers of heart failure (HF) taking into account the clinical and paraclinical data of the patient, and to analyze its change during therapy.Material and ...
E. V. Kolesnikova +3 more
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Structures of NS5 Methyltransferase from Zika Virus
Cell Reports, 2016 The Zika virus (ZIKV) poses a major public health emergency. To aid in the development of antivirals, we present two high-resolution crystal structures of the ZIKV NS5 methyltransferase: one bound to S-adenosylmethionine (SAM) and the other bound to SAM ...
Javier Coloma +4 more
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Structural Insights into the Regulation Mechanism of Small GTPases by GEFs
Molecules, 2019 Small GTPases are key regulators of cellular events, and their dysfunction causes many types of cancer. They serve as molecular switches by cycling between inactive guanosine diphosphate (GDP)-bound and active guanosine triphosphate (GTP)-bound states ...
Sachiko Toma-Fukai, Toshiyuki Shimizu
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