Results 31 to 40 of about 29,370 (164)
A Long Overdue Targeted Treatment for KRAS Mutations in NSCLC: Spotlight on Adagrasib
Lung Cancer: Targets and Therapy, 2022 Danielle Brazel,1 Zhaohui Arter,1 Misako Nagasaka1– 3 1Department of Medicine, University of California Irvine School of Medicine, Orange, CA, USA; 2Chao Family Comprehensive Cancer Center, Orange, CA, USA; 3St.
Brazel D, Arter Z, Nagasaka M
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Synthesis of Guanosine 5'-Diphosphate.
Chemical and Pharmaceutical Bulletin, 1959 Guanosine 5'-diphosphate was synthesized from guanosine 5'-monophosphate by the reaction of benzyl hydrogen phosphoramidate, followed by the catalytic hydrogenolysis, in a yield of 38%. The effect of water in the reaction media and correlation of the yield with the amount of reagents are discussed.
Ueda, Tohru, Ohtsuka, Eiko
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Frontiers in Physiology, 2015 Aquatic and semiaquatic mammals have the capacity of breath hold (apnea) diving. Northern elephant seals (Mirounga angustirostris) have the ability to perform deep and long duration dives; during a routine dive, adults can hold their breath for 25 min ...
Myrna eBarjau Perez-Milicua +3 more
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Micro, 2022 Nucleoside diphosphate kinase (NDPK) enzyme in the sarcolemma membrane is crucial for the synthesis of cyclic adenosine monophosphate (cAMP) to maintain the calcium ion balance.
Andrey Zaznaev, Isaac Macwan
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Focus on Cdc42 in Breast Cancer: New Insights, Target Therapy Development and Non-Coding RNAs
Cells, 2019 Breast cancer is the most common malignant tumors in females. Although the conventional treatment has demonstrated a certain effect, some limitations still exist.
Yu Zhang +5 more
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Journal of Analytical Science and Technology, 2010 Bacterial SpoT is a Mn2+-dependent pyrophosphohydrolase to hydrolyze guanosine 3’-diphosphate-5’-diphosphate to guanosine diphosphate and pyrophosphate.
Dawei Sun, Hye-Yeon Kim, Young Ho Jeon
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Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response
Microbial Cell, 2019 In our recent publication (Zhang et al., 2019), we demonstrate an interesting mode of regulation of purine metabolism unique to Proteobacteria. In this microreview, we would like to reflect on the ideas put forward, with special focus on protein domain ...
René Lysdal Bærentsen +2 more
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Regulation of Bacteriophage λ Development by Guanosine 5′-Diphosphate-3′-diphosphate
Virology, 1999 On infection of its host, Escherichia coli, bacteriophage lambda can follow one of two alternative developmental pathways: lytic or lysogenic. Here we demonstrate that the "lysis-versus-lysogenization" decision is influenced by guanosine tetraphosphate (ppGpp), a nucleotide that is synthesized in E. coli cells in response to amino acid or carbon source
Słomińska, Monika +2 more
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F1000Research, 2017 Nucleoside triphosphate (NTP)s, like ATP (adenosine 5’-triphosphate) and GTP (guanosine 5’-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel all cellular ATPases (adenosine triphosphatases) and GTPases (guanosine ...
Diana Zala +6 more
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F1000Research, 2017 Nucleoside triphosphate (NTP)s, like ATP (adenosine 5’-triphosphate) and GTP (guanosine 5’-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel all cellular ATPases (adenosine triphosphatases) and GTPases (guanosine ...
Diana Zala +6 more
doaj +1 more source