Results 31 to 40 of about 30,526 (262)
Rho GTPases in Skeletal Muscle Development and Homeostasis
Rho guanosine triphosphate hydrolases (GTPases) are molecular switches that cycle between an inactive guanosine diphosphate (GDP)-bound and an active guanosine triphosphate (GTP)-bound state during signal transduction. As such, they regulate a wide range
Sonia Rodríguez-Fdez, Xosé R. Bustelo
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Role of (p)ppGpp in Viability and Biofilm Formation of Actinobacillus pleuropneumoniae S8. [PDF]
Actinobacillus pleuropneumoniae is a Gram-negative bacterium and the cause of porcine pleuropneumonia. When the bacterium encounters nutritional starvation, the relA-dependent (p)ppGpp-mediated stringent response is activated.
Gang Li +5 more
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Rhamnose-Containing Compounds: Biosynthesis and Applications
Rhamnose-associated molecules are attracting attention because they are present in bacteria but not mammals, making them potentially useful as antibacterial agents. Additionally, they are also valuable for tumor immunotherapy.
Siqiang Li +6 more
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In vitro degradation of guanosine 5'-diphosphate, 3'-diphosphate. [PDF]
The degradation of guanosine 5'-diphosphate,3'-diphosphate (ppGpp) by the "crude" ribosomal fraction of Escherichia coli CP78 (rel+, spoT+) was demonstrated and characterized. When the 3'-pyrophosphoryl group of ppGpp was hydrolyzed, the primary degradation product was 5'-GDP. Phosphorylation of ppGpp to guanosine 5'-triphosphate,3'-diphosphate (pppGpp)
J Sy
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Characterization of the RelBbu Regulon in Borrelia burgdorferi Reveals Modulation of Glycerol Metabolism by (p)ppGpp. [PDF]
The bacterial stringent response is triggered by deficiencies of available nutrients and other environmental stresses. It is mediated by 5'-triphosphate-guanosine-3'-diphosphate and 5'-diphosphate-guanosine-3'-diphosphate (collectively (p)ppGpp) and ...
Julia V Bugrysheva +6 more
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Role of ARHGEF3 as a GEF and mTORC2 Regulator
Guanine nucleotide exchange factors (GEFs) activate GTPases by stimulating the release of guanosine diphosphate to permit the binding of guanosine triphosphate.
Sana Abdul Khaliq +5 more
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Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
Summary: G proteins are major signaling partners for G protein-coupled receptors (GPCRs). Although stepwise structural changes during GPCR–G protein complex formation and guanosine diphosphate (GDP) release have been reported, no information is available
Donghoon Ahn +12 more
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AMP-activated protein kinase (AMPK) activation has an antiapoptotic effect in endothelial cells, but the mechanisms involved remain unclear. Here, we investigated whether AMPK activation could inhibit palmitate-induced apoptosis through suppression of ...
Ji-Eun Kim +5 more
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Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer [PDF]
Background: S-PM2 is a phage capable of infecting strains of unicellular cyanobacteria belonging to the genus Synechococcus. S-PM2, like other myoviruses infecting marine cyanobacteria, encodes a number of bacterial-like genes. Amongst these genes is one
M. J. Bryan (7607582) +23 more
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NUCLEOSIDE-DIPHOSPHATASE OF CESTODE BOTHRIOCEPHALUS SCORPII (CESTODA: BOTHRIOCEPHALIDAE)
Objective of research: To study the activities and properties of nucleoside- diphosphatase (NDPase) in cestode Bothriocephalus scorpii.Materials and methods: Cestodes were homogenized with 10 vol. of extraction medium. NDPase was detected in mitochondria
E. A. Burenina
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