Results 41 to 50 of about 12,147 (240)

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

Angewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu, Hiroyuki Asanuma, Keiji Murayama   +2 more
wiley   +2 more sources

Fluid Vesicles in Flow [PDF]

, 2014
We review the dynamical behavior of giant fluid vesicles in various types of external hydrodynamic flow. The interplay between stresses arising from membrane elasticity, hydrodynamic flows, and the ever present thermal fluctuations leads to a rich ...
Abreu, David, Levant, Michael, Seifert, Udo, Steinberg, Victor   +3 more
core   +1 more source

Dataset of asymmetric giant unilamellar vesicles prepared via hemifusion: Observation of anti-alignment of domains and modulated phases in asymmetric bilayers.

Data in Brief, 2021
The data provided with this paper are confocal fluorescence images of symmetric giant unilamellar vesicles (GUVs) and asymmetric giant unilamellar vesicles (aGUVs).
Thais A. Enoki, Joy Wu, Frederick A. Heberle, Gerald W. Feigenson   +3 more
doaj   +1 more source

A novel minimal in vitro system for analyzing HIV-1 Gag mediated budding

, 2014
A biomimetic minimalist model membrane was used to study the mechanism and kinetics of cell-free in vitro HIV-1 Gag budding from a giant unilamellar vesicle (GUV).
Gill, Sarjeet, Gui, Dong, Gupta, Sharad, Huang, I-Chueh, Mohideen, Umar, Rao, A. L. N., Xu, Jun, Zandi, Roya   +7 more
core   +1 more source

Molecular rheometry: direct determination of viscosity in L-o and L-d lipid phases via fluorescence lifetime imaging [PDF]

, 2013
Understanding of cellular regulatory pathways that involve lipid membranes requires the detailed knowledge of their physical state and structure. However, mapping the viscosity and diffusion in the membranes of complex composition is currently a non ...
Agnieszka Olzyńska, Akashi, Alamiry, Benda, Beranova, Capoulade, Chen, Dertinger, Duncan R. Casey, Eggeling, Förster, Gokhan Yahioglu, Haidekker, Haidekker, Hoekstra, Hope, Ikonen, Jana Humpolíčková, Kahya, Kuimova, Kuimova, Kuimova, Levitt, Marina K. Kuimova, Martin Hof, Martin Štefl, Oscar Ces, Pan, Petrov, Philip Yip, Saffman, Sankaran, Schutz, Smith, Sykora, Veatch, Wohland, Yilei Wu   +37 more
core   +2 more sources

Effects of membrane potentials on the electroporation of giant unilamellar vesicles.

PLoS ONE, 2023
Living organisms maintain a resting membrane potential, which plays an important role in various biophysical and biological processes. In the context of medical applications, irreversible electroporation (IRE) is a non-thermal and minimally invasive ...
Md Abdul Wadud, Mohammad Abu Sayem Karal, Md Moniruzzaman, Md Mamun Or Rashid   +3 more
doaj   +1 more source

Shaping Giant Membrane Vesicles in 3D-Printed Protein Hydrogel Cages

, 2020
Giant unilamellar phospholipid vesicles are attractive starting points for constructing minimal living cells from the bottom-up. Their membranes are compatible with many physiologically functional modules and act as selective barriers, while retaining a ...
Eto, H., Franquelim, H., Heymann, M., Jia, H., Litschel, T., Schwille, P.   +5 more
core   +1 more source

Membrane localization of actin filaments stabilizes giant unilamellar vesicles against external deforming forces

European Journal of Cell Biology
Actin organization is crucial for establishing cell polarity, which influences processes such as directed cell motility and division. Despite its critical role in living organisms, achieving similar polarity in synthetic cells remains challenging.
Andreas Fink, Sunnatullo Fazliev, Tobias Abele, Joachim P. Spatz, Kerstin Göpfrich, Elisabetta Ada Cavalcanti-Adam   +5 more
doaj   +1 more source

Temperature-Promoted Giant Unilamellar Vesicle (GUV) Aggregation: A Way of Multicellular Formation

Current Issues in Molecular Biology, 2023
The evolution of unicellular to multicellular life is considered to be an important step in the origin of life, and it is crucial to study the influence of environmental factors on this process through cell models in the laboratory.
Xinmao Wang, Yangruizi Zhang, Maobin Xie, Zhibiao Wang, Hai Qiao   +4 more
doaj   +1 more source

Bottom-up assembly of functional intracellular synthetic organelles by droplet-based microfluidics

, 2020
Bottom-up synthetic biology has directed most efforts toward the construction of artificial compartmentalized systems that recreate living cell functions in their mechanical, morphological, or metabolic characteristics.
Platzman, I., Schröter, M., Spatz, J., Staufer, O.   +3 more
core   +1 more source