Results 51 to 60 of about 24,574 (211)

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

Additional file 1 of Housekeeping gene gyrA, a potential molecular marker for Bacillus ecology study

, 2022
Additional file 1: Figure S1 The agarose gel electrophoresis of DNA amplification products of three gyrA gene primer pairs: gyrA1 (A), gyrA2 (B) and gyrA3 (C). 1-7 indicates strains LY18, LY25, LY37, FZB42, SXL408, SXL277 and ACCC01043.
Youzhi Miao (3480608), Zhihui Xu (14016028), Ruifu Zhang (331550), Polonca Štefanič (13016673), Yan Liu (25061), Nan Zhang (46264), Ines Mandic-Mulec (201343), Weibing Xun (5776415), Qirong Shen (404759), Yansheng Xue (14016025)   +9 more
core   +1 more source

Spontaneous quinolone resistance in Serratia marcescens due to a mutation in gyrA [PDF]

Antimicrobial Agents and Chemotherapy, 1991
Spontaneous quinolone-resistant mutants of MP050, a quinolone-susceptible clinical strain of Serratia marcescens, were isolated on nutrient agar containing 0.5 microgram of ciprofloxacin per ml. One mutant, designated MP051, was selected for further study.
B L, Masecar, N J, Robillard
openaire   +2 more sources

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Genetic and physical organization of the cloned gyrA and gyrB genes of Bacillus subtilis. [PDF]

, 1985
An 8-kilobase fragment already known to contain the gyrA gene of Bacillus subtilis was shown to encode the gyrB gene as well. Plasmids containing this fragment can rescue both B. subtilis gyrA and gyrB mutants and complement Escherichia coli gyrA mutants.
Bott, Kenneth F., Lampe, Mary F.
core   +1 more source

Frequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic review.

PLoS ONE, 2015
BackgroundThe detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of ...
Elisea Avalos, Donald Catanzaro, Antonino Catanzaro, Theodore Ganiats, Stephanie Brodine, John Alcaraz, Timothy Rodwell   +6 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Validation of the T86I mutation in the gyrA gene as a highly reliable real time PCR target to detect Fluoroquinolone-resistant Campylobacter jejuni

BMC Infectious Diseases, 2020
Background Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and increasing rates of fluoroquinolone (FQ) resistance in C. jejuni are a major public health concern.
Nereyda Espinoza, Jesús Rojas, Simon Pollett, Rina Meza, Lilian Patiño, Manuel Leiva, Máximo Camiña, Manuela Bernal, Nathanael D. Reynolds, Ryan Maves, Drake H. Tilley, Matthew Kasper, Mark P. Simons   +12 more
doaj   +1 more source

Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children

iMetaOmics, EarlyView.
Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao, Yuchen Wu, Zhaoju Deng, Hanyu Wang, Can Cui, Jianzhong Shen, Julian Parkhill, Yang Wang, Rong Zhang, Dejun Liu   +9 more
wiley   +1 more source

Detection of gyrA and parC Genes in Clinical Acinetobacter Baumannii Isolates

Al-Mustansiriyah Journal of Science, 2022
100 isolates of Acinetobacter baumannii were collected from different clinical sources including (blood, sputum and burns) from hospitals in Baghdad - Iraq. In order to investigate its resistance to fluoroquinolones. MIC assay for ciprofloxacin was performed using E-test, and PCR assay for gry A and parC genes.
openaire   +2 more sources