Results 31 to 40 of about 24,574 (211)
Veterinární Medicína, 2016 This study was aimed at investigating the resistance to antimicrobial agents and to assess the predominant molecular mechanisms of fluoroquinolone resistance in faecal E. coli strains isolated from chickens farmed in central Poland.
A. Lenart-Boron +2 more
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Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance [PDF]
Antimicrobial Agents and Chemotherapy, 1995 Spontaneous quinolone-resistant mutants obtained from Salmonella typhimurium Su694 were screened for mutations by direct DNA sequencing of an amplified PCR gyrA fragment. Substitutions Ser-83-->Phe (Ser83Phe), Ser83Tyr, Asp87Tyr, and Asp87Asn and double mutation Ala67Pro-Gly81Ser, which resulted in decreased sensitivities to ciprofloxacin, enoxacin,
F, Reyna +3 more
openaire +2 more sources
Molecular Detection of gyrA Mutation in Clinical Strains of Klebsiella pneumoniae
Iranian Journal of Public Health, 2022 Background: Multi-drug resistant (MDR) Klebsiella pneumoniae strains cause the majority of community acquired and life-threatening infections. We aimed to detect the gyrA mutations in the clinical strains of nalidixic acid and ciprofloxacin resistant K. pneumoniae isolated from the patients with urinary tract infections.
Zeinab Ahmadi +3 more
openaire +3 more sources
Study of gyrA S83R Mutation Rate in Vancomycin Resistant Entrococcus Faecium
Trends in Peptide and Protein Sciences, 2017 Enterococci are among Gram-positive cocci and are common inhabitants of the human gastrointestinal tract and enough potent to cause serious infections such as bacteremia, urinary tract infections (UTIs) and endocarditis.
Nasim Rahimi Rad +2 more
doaj +1 more source
High frequency of mutations in gyrA gene associated with quinolones resistance in uropathogenic Escherichia coli isolates from the north of Iran [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Regarding the global burden of uropathogenic Escherichia coli (UPEC) infections, prevention and treatment of such infections play a significant role in healthcare management.
Mohammad Shenagari +3 more
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Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC. [PDF]
PLoS ONE, 2018 Mutations in gyrA are the primary cause of quinolone resistance encountered in gram-negative clinical isolates. The prospect of this work was to analyze the role of gyrA mutations in eliciting high quinolone resistance in uropathogenic E.coli (UPEC ...
Lesley R Varughese +5 more
doaj +1 more source
Molecular Characterization of Fluoroquinolone-Resistant Bartonella bacilliformis
Pathogens, 2021 The presence of amino acid changes in GyrA, GyrB, ParC, ParE, and in a proposed chromosomal chloramphenicol acetyl transferase (CAT), as well as mutations at 23S rRNA, were established by PCR and sequencing in 38 B.
Giovanna Mendoza-Mujica +2 more
doaj +1 more source
Gyrase inhibitors can increase gyrA expression and DNA supercoiling [PDF]
Journal of Bacteriology, 1989 Treatment of bacterial cells with inhibitors of gyrase at high concentration leads to relaxation of DNA supercoils, presumably through interference with the supercoiling activity of gyrase. Under certain conditions, however, the inhibitors can also increase supercoiling.
R J, Franco, K, Drlica
openaire +2 more sources
BMC Microbiology, 2020 Background Neisseria meningitidis (N.meningitidis) bacteria belonging to clonal complex 4821 (CC4821) have been mainly reported in China and have been characterized by a high resistance rate to ciprofloxacin (CIP). The aim of this study was to assess the
Pan Zhao +4 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2012 Objective: The study aimed to investigate gyrA and gyrB mutations in Mycobacterium tuberculosis (MTB) clinical strains from 93 patients with pulmonary tuberculosis in Hubei Province, China, and analyze the association between mutation patterns of the ...
Jun Chen +8 more
doaj +1 more source