Results 11 to 20 of about 24,574 (211)

Cloning the gyrA gene of Bacillus subtilis [PDF]

Nucleic Acids Research, 1984
We have isolated an eight kilobase fragment of Bacillus subtilis DNA by specific integration and excision of a plasmid containing a sequence adjacent to ribosomal operon rrn O.
Bott, Kenneth F., Lampe, Mary F.
core   +4 more sources

Homing events in the gyrA gene of some mycobacteria [PDF]

Proceedings of the National Academy of Sciences, 1996
The A subunit of DNA gyrase in Mycobacterium leprae, unlike its counterpart in Mycobacterium tuberculosis, is produced by protein splicing as its gene, gyrA, harbors a 1260-bp in-frame insertion encoding an intein, a putative homing endonuclease ...
Fsihi, H, Vincent, V, Cole, S T
core   +3 more sources

gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya

BMC Microbiology, 2019
Background Phenotypic fluoroquinolone resistance was first reported in Western Kenya in 2009 and later in Coastal Kenya and Nairobi. Until recently gonococcal fluoroquinolone resistance mechanisms in Kenya had not been elucidated.
Mary Wandia Kivata, Margaret Mbuchi, Fredrick Lunyagi Eyase, Wallace Dimbuson Bulimo, Cecilia Katunge Kyanya, Valerie Oundo, Simon Wachira Muriithi, Ben Andagalu, Wilton Mwema Mbinda, Olusegun O. Soge, R. Scott McClelland, Willy Sang, James D. Mancuso   +12 more
doaj   +2 more sources

Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound infections.
Abdollah Ardebili, Abdolaziz Rastegar Lari, Maryam Beheshti, Elnaz Rastegar Lari   +3 more
doaj   +3 more sources

Implicación de diversos mecanismos de resistencia a quinolonas en bacilos Gram-negativos: Diseño de una nueva fluoroquinolona [PDF]

, 2008
[spa] DE LA TESIS: Desde la aparición de las quinolonas, las resistencias bacterianas a las mismas han evolucionado de forma paralela. Conforme han ido apareciendo nuevas moléculas con mayor capacidad bactericida y mejores parámetros farmacodinámicos ...
Sánchez Céspedes, Javier
core   +6 more sources

Fluoroquinolone resistance in Streptococcus pneumoniae:Evidence that gyrA mutations arise at a lower rate and that mutation in gyrA or parC predisposes to further mutation

Microbial drug resistance (Larchmont, N.Y.), 2003
Fluoroquinolones are being increasingly used for acute lower respiratory tract infection where Streptococcus pneumoniae is the most important bacterial pathogen. S.
Voelker, Leroy L., Traini, Chris, Ambler, Jane E., Gillespie, Stephen H., Dickens, Anne   +4 more
core   +3 more sources

Mutations in the gyrA, parC, and mexR genes provide functional insights into the fluoroquinolone-resistant Pseudomonas aeruginosa isolated in Vietnam

Infection and Drug Resistance, 2018
Kinh Van Nguyen,1,2,* Trung Vu Nguyen,1,3,* Hang Thi Thuy Nguyen,4 Duyet Van Le1 1Clinical Laboratories, National Hospital for Tropical Diseases, 2Infectious Department, Hanoi Medical University, 3Microbiology Department, Hanoi Medical University ...
Nguyen KV, Nguyen TV, Nguyen HTT, Le DV
doaj   +1 more source

Combating Campylobacter Resistance in Moroccan Poultry Using Essential Oil-Ciprofloxacin Combination. [PDF]

Vet Med Sci
With an estimated prevalence of 15.52% in Moroccan poultry, Campylobacter species pose a significant food safety concern. We investigated whether essential oils (EOs) could restore the efficacy of ciprofloxacin against multidrug‐resistant (MDR) strains.
Soubai Z, Ziyate N, Rais R, Elhrech H, Aguerd O, Bouyahya A, Benali T, Akhazzane M, Mahir H, Fellahi S, Al Abdulmonem W, Houssni IE, Attarassi B, Auajjar N.   +13 more
europepmc   +2 more sources

Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health. [PDF]

Environ Microbiol Rep
Anaerobic digester metagenomes revealed diverse resistance‐associated annotations and antibiotic target loci, highlighting their potential role in environmental AMR surveillance. The findings emphasise the need for cautious interpretation of resistome profiles and further host‐resolved analyses to determine the mobility and clinical relevance of ...
Olasupo OA, Olaniyan OP, Akinde SB, Adesoye AA, Ajadi FA, Obire O, Oladipo EK, Sule WF, Oyinloye OE, Salami AA, Fajoyegbe ES, Ajani AJ, Ojo O.   +12 more
europepmc   +2 more sources

Mutación en el gen gyrA de aislamientos hospitalarios de Acinetobacter baumannii en Montería, Colombia Mutation of the gyrA Gen in Acinetobacter baumannii Nosocomial Isolates in Monteria, Colombia

Infectio, 2010
Objetivo: Determinar las mutaciones del gen gyrA asociadas con la resistencia a fluoroquinolonas en Acinetobacter baumannii. Materiales y métodos: Entre agosto de 2005 y febrero de 2007 se recolectaron 23 aislamientos de A.
Pedro Martínez, Salim Máttar
doaj   +1 more source