Results 11 to 20 of about 252,628 (301)
Transcription regulation of HYPK by Heat Shock Factor 1. [PDF]
PLoS ONE, 2014 HYPK (Huntingtin Yeast Partner K) was originally identified by yeast two-hybrid assay as an interactor of Huntingtin, the protein mutated in Huntington's disease.
Srijit Das, Nitai Pada Bhattacharyya
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Transcription factor cooperativity with heat shock factor 1 [PDF]
Transcription, 2011 The heat shock response has been characterized by the induction of major heat shock proteins that suppress protein aggregation by facilitating protein folding. Recently, we found that mammalian heat shock factor 1, a master regulator of HSP genes, regulates non-HSP genes that suppress protein aggregation by controlling protein degradation in ...
Naoki, Hayashida +2 more
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Inhibition of Heat Shock Transcription Factor by GR [PDF]
Molecular Endocrinology, 2001 The GR is a hormone-activated transcription factor that acts to regulate specific gene expression. In the absence of hormone, the GR and other steroid receptors have been shown to form complexes with several mammalian heat shock proteins. As heat shock proteins are produced by cells as an adaptive response to stress, speculation has existed that ...
S A, Wadekar +3 more
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Cell Reports, 2023 Summary: Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is tuned quantitatively remains poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat shock response, acts ...
Meng Xu +8 more
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Immunolocalization of anti-hsf1 to the acetabular glands of infectious schistosomes suggests a non-transcriptional function for this transcriptional activator. [PDF]
PLoS Neglected Tropical Diseases, 2014 Schistosomiasis is a chronically debilitating disease caused by parasitic worms of the genus Schistosoma, and it is a global problem affecting over 240 million people.
Kenji Ishida +3 more
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Antiproliferative prostaglandins activate heat shock transcription factor. [PDF]
Proceedings of the National Academy of Sciences, 1992 Treatment of human K562 erythroleukemia cells with the antiproliferative prostaglandin A1 results in the elevated transcription of two heat shock genes, HSP70 and HSP90. Parallel with increased heat shock gene transcription is the activation of heat shock transcription factor.
AMICI, CARLA +3 more
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Proteolytic mapping of heat shock transcription factor domains [PDF]
Protein Science, 1996 AbstractHeat shock transcription factors (HSFs) of higher eukaryotes respond to physical and cellular stress signals by tri‐merizing, binding to a specific site on DNA, and transactivating genes encoding the heat shock proteins. In this work, limited proteolysis was used as a biochemical probe of the domain organization of Drosophila HSF.
M, Zhong, C, Wu
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Phosphorylation of Drosophila heat shock transcription factor
Cell Stress & Chaperones, 1999 The role that phosphorylation plays in regulating heat shock factor (HSF) function and activity has been the subject of several studies. Here, we demonstrate that Drosophila melanogaster HSF (DmHSF) is a phosphoprotein that is multiply phosphorylated at some sites and is dephosphorylated at others upon heat shock.
M, Fritsch, C, Wu
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Research progress on heat shock transcription factors in insects
浙江大学学报. 农业与生命科学版, 2022 Insects are capable of inducing the production of heat shock proteins when exposed to environmental stresses or under specific physiological conditions such as diapause.
ZHANG Chao +6 more
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Complex Regulation of the Yeast Heat Shock Transcription Factor [PDF]
Molecular Biology of the Cell, 2000 The yeast heat shock transcription factor (HSF) is regulated by posttranslational modification. Heat and superoxide can induce the conformational change associated with the heat shock response. Interaction between HSF and the chaperone hsp70 is also thought to play a role in HSF regulation.
J J, Bonner +5 more
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