Results 21 to 30 of about 134,612 (257)
Heat Shock Response, Heat Shock Transcription Factor and Cell Aging
Neurosignals, 1996 A characteristic feature of aging is a progressive impairment in the ability to adapt to environmental challenges. The purpose of this article is to review the evidence of an attenuated response to heat and physiological stresses in a number of mammalian aging model systems, including the human diploid fibroblasts in culture, whole animals and animal ...
Y K, Lee, D, Manalo, A Y, Liu
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Research progress on heat shock transcription factors in insects
浙江大学学报. 农业与生命科学版, 2022 Insects are capable of inducing the production of heat shock proteins when exposed to environmental stresses or under specific physiological conditions such as diapause.
ZHANG Chao +6 more
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Dynamics of the full length and mutated heat shock factor 1 in human cells. [PDF]
PLoS ONE, 2013 Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress.
Gaëtan Herbomel +7 more
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Characteristics and Regulating Roles of Wheat TaHsfA2-13 in Abiotic Stresses
Frontiers in Plant Science, 2022 Heat shock transcription factor (Hsf) exists widely in eukaryotes and responds to various abiotic stresses by regulating the expression of downstream transcription factors, functional enzymes, and molecular chaperones.
Xiangzhao Meng +10 more
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Cell Cycle Regulation by Heat Shock Transcription Factors
Cells, 2022 Cell division and cell cycle mechanism has been studied for 70 years. This research has revealed that the cell cycle is regulated by many factors, including cyclins and cyclin-dependent kinases (CDKs). Heat shock transcription factors (HSFs) have been noted as critical proteins for cell survival against various stresses; however, recent studies suggest
Yasuko Tokunaga +2 more
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A model for handling cell stress
eLife, 2016 The heat shock response in yeast is regulated by the interaction between a chaperone protein and a heat shock transcription factor, and fine-tuned by phosphorylation.
Laura Le Breton, Matthias P Mayer
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Molecular Mechanisms of Heat Shock Factors in Cancer
Cells, 2020 Malignant transformation is accompanied by alterations in the key cellular pathways that regulate development, metabolism, proliferation and motility as well as stress resilience. The members of the transcription factor family, called heat shock factors (
Mikael Christer Puustinen, Lea Sistonen
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Activation of Heat Shock Transcription Factor 1 in Atherosclerosis [PDF]
The American Journal of Pathology, 2003 Previous work established that increased expression of heat shock proteins (HSPs) in the vessel wall might evoke proinflammatory and autoimmune reactions in the pathogenesis of atherosclerosis. The present study was designed to further scrutinize the molecular mechanisms of HSP expression involving activation of heat shock transcription factors (HSFs ...
Bernhard, Metzler +6 more
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Proteolytic mapping of heat shock transcription factor domains [PDF]
Protein Science, 1996 AbstractHeat shock transcription factors (HSFs) of higher eukaryotes respond to physical and cellular stress signals by tri‐merizing, binding to a specific site on DNA, and transactivating genes encoding the heat shock proteins. In this work, limited proteolysis was used as a biochemical probe of the domain organization of Drosophila HSF.
M, Zhong, C, Wu
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Electronic Journal of Plant Breeding, 2020 In the present investigation, differential expression of two transcription factor genes (HsfA4d and HsfB2a) and a heat shock protein (ClpD1/HSP100) was evaluated in the rice varieties N22 and Co 51 using qRT-PCR.
Rishima Maheendran, V. Soundarrajan, N. M. Manikanda Boopathi, R. Gnanam, V. Geethalakshmi and P. Meenakshisundaram
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