Results 21 to 30 of about 252,628 (301)
Regulatory Mechanisms of Heat Stress Response and Thermomorphogenesis in Plants
Plants, 2022 As worldwide warming intensifies, the average temperature of the earth continues to increase. Temperature is a key factor for the growth and development of all organisms and governs the distribution and seasonal behavior of plants. High temperatures lead
Yunzhuan Zhou +3 more
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Modulation of tolerance by mutant heat shock transcription factors [PDF]
Cell Stress & Chaperones, 1999 It ought to be possible to recruit normal cellular defenses to mitigate ischemia/reperfusion damage and to reduce toxicity of chemotherapeutic drugs. Stress-preconditioned cells acquire a tolerant state characterized by increased resistance to such insults. This state is widely believed to be mediated, partially, by heat shock proteins (Hsps). Indirect
W, Xia +5 more
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Cell Cycle Regulation by Heat Shock Transcription Factors
Cells, 2022 Cell division and cell cycle mechanism has been studied for 70 years. This research has revealed that the cell cycle is regulated by many factors, including cyclins and cyclin-dependent kinases (CDKs). Heat shock transcription factors (HSFs) have been noted as critical proteins for cell survival against various stresses; however, recent studies suggest
Yasuko Tokunaga +2 more
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Characteristics and Regulating Roles of Wheat TaHsfA2-13 in Abiotic Stresses
Frontiers in Plant Science, 2022 Heat shock transcription factor (Hsf) exists widely in eukaryotes and responds to various abiotic stresses by regulating the expression of downstream transcription factors, functional enzymes, and molecular chaperones.
Xiangzhao Meng +10 more
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Heat shock stimulation of a tilapia heat shock protein 70 promoter is mediated by a distal element [PDF]
, 2001 peer reviewedWe reported previously that a tilapia (Oreochromis mossambicus) heat shock protein 70 (HSP70) promoter is able to confer heat shock response on a reporter gene after transient expression both in cell culture and in microinjected zebrafish ...
Di Martino, Emmanuel +3 more
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Heat Shock Response, Heat Shock Transcription Factor and Cell Aging
Neurosignals, 1996 A characteristic feature of aging is a progressive impairment in the ability to adapt to environmental challenges. The purpose of this article is to review the evidence of an attenuated response to heat and physiological stresses in a number of mammalian aging model systems, including the human diploid fibroblasts in culture, whole animals and animal ...
Y K, Lee, D, Manalo, A Y, Liu
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Dynamics of the full length and mutated heat shock factor 1 in human cells. [PDF]
PLoS ONE, 2013 Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress.
Gaëtan Herbomel +7 more
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A model for handling cell stress
eLife, 2016 The heat shock response in yeast is regulated by the interaction between a chaperone protein and a heat shock transcription factor, and fine-tuned by phosphorylation.
Laura Le Breton, Matthias P Mayer
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Activation of Heat Shock Transcription Factor 1 in Atherosclerosis [PDF]
The American Journal of Pathology, 2003 Previous work established that increased expression of heat shock proteins (HSPs) in the vessel wall might evoke proinflammatory and autoimmune reactions in the pathogenesis of atherosclerosis. The present study was designed to further scrutinize the molecular mechanisms of HSP expression involving activation of heat shock transcription factors (HSFs ...
Bernhard, Metzler +6 more
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Molecular Mechanisms of Heat Shock Factors in Cancer
Cells, 2020 Malignant transformation is accompanied by alterations in the key cellular pathways that regulate development, metabolism, proliferation and motility as well as stress resilience. The members of the transcription factor family, called heat shock factors (
Mikael Christer Puustinen, Lea Sistonen
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