Research progress on heat shock transcription factors in insects
Insects are capable of inducing the production of heat shock proteins when exposed to environmental stresses or under specific physiological conditions such as diapause.
ZHANG Chao +6 more
doaj +1 more source
Antiproliferative prostaglandins activate heat shock transcription factor. [PDF]
Treatment of human K562 erythroleukemia cells with the antiproliferative prostaglandin A1 results in the elevated transcription of two heat shock genes, HSP70 and HSP90. Parallel with increased heat shock gene transcription is the activation of heat shock transcription factor.
AMICI, CARLA +3 more
openaire +3 more sources
Characteristics and Regulating Roles of Wheat TaHsfA2-13 in Abiotic Stresses
Heat shock transcription factor (Hsf) exists widely in eukaryotes and responds to various abiotic stresses by regulating the expression of downstream transcription factors, functional enzymes, and molecular chaperones.
Xiangzhao Meng +10 more
doaj +1 more source
Heat Shock Response, Heat Shock Transcription Factor and Cell Aging
A characteristic feature of aging is a progressive impairment in the ability to adapt to environmental challenges. The purpose of this article is to review the evidence of an attenuated response to heat and physiological stresses in a number of mammalian aging model systems, including the human diploid fibroblasts in culture, whole animals and animal ...
Y K, Lee, D, Manalo, A Y, Liu
openaire +2 more sources
Dynamics of the full length and mutated heat shock factor 1 in human cells. [PDF]
Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress.
Gaëtan Herbomel +7 more
doaj +1 more source
Modulation of tolerance by mutant heat shock transcription factors [PDF]
It ought to be possible to recruit normal cellular defenses to mitigate ischemia/reperfusion damage and to reduce toxicity of chemotherapeutic drugs. Stress-preconditioned cells acquire a tolerant state characterized by increased resistance to such insults. This state is widely believed to be mediated, partially, by heat shock proteins (Hsps). Indirect
W, Xia +5 more
openaire +2 more sources
Activation of Heat Shock Transcription Factor 1 in Atherosclerosis [PDF]
Previous work established that increased expression of heat shock proteins (HSPs) in the vessel wall might evoke proinflammatory and autoimmune reactions in the pathogenesis of atherosclerosis. The present study was designed to further scrutinize the molecular mechanisms of HSP expression involving activation of heat shock transcription factors (HSFs ...
Bernhard, Metzler +6 more
openaire +2 more sources
A model for handling cell stress
The heat shock response in yeast is regulated by the interaction between a chaperone protein and a heat shock transcription factor, and fine-tuned by phosphorylation.
Laura Le Breton, Matthias P Mayer
doaj +1 more source
Molecular Mechanisms of Heat Shock Factors in Cancer
Malignant transformation is accompanied by alterations in the key cellular pathways that regulate development, metabolism, proliferation and motility as well as stress resilience. The members of the transcription factor family, called heat shock factors (
Mikael Christer Puustinen, Lea Sistonen
doaj +1 more source
Genome-wide transcriptional profiles during temperature and oxidative stress reveal coordinated expression patterns and overlapping regulons in rice. [PDF]
Genome wide transcriptional changes by cold stress, heat stress and oxidative stress in rice seedlings were analyzed. Heat stress resulted in predominant changes in transcripts of heat shock protein and heat shock transcription factor genes, as well as ...
Dheeraj Mittal +2 more
doaj +1 more source

