Integrative analysis of the heat shock response in Aspergillus fumigatus [PDF]
, 2010 Background Aspergillus fumigatus is a thermotolerant human-pathogenic mold and the most common cause of invasive aspergillosis (IA) in immunocompromised patients. Its predominance is based on several factors most of which are still unknown.
Daniela Albrecht +3 more
core +2 more sources
Surviving the heat of the moment : a fungal pathogens perspective [PDF]
, 2013 Peer reviewedPublisher ...
Cowen, Leah E, Leach, Michelle D
core +5 more sources
Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains [PDF]
, 2003 EMTREE drug terms: fungal protein; heat shock protein 90; hybrid protein; transcription factor EMTREE medical terms: amino terminal sequence; article; carboxy terminal sequence; DNA binding; DNA binding domain; expression vector; Gal4p domain; gene ...
Millson, S. H. +2 more
core +1 more source
Role of Heat Shock Factors in Stress-Induced Transcription [PDF]
, 2017 Heat shock proteins (HSP) are rapidly induced after stresses such as heat shock and accumulate at high concentrations in cells. HSP induction involves primarily a family of heat shock transcription factors (HSF) that bind the heat shock elements of the HSP genes and mediate transcription in trans.
Ayesha, Murshid +3 more
openaire +2 more sources
Direct Sensing of Heat and Oxidation by Drosophila Heat Shock Transcription Factor [PDF]
Molecular Cell, 1998 The heat shock transcription factor HSF activates expression of its target genes in response to elevated temperatures and chemical or physiological stress. A key step in the activation process involves the formation of HSF homotrimers, leading to high-affinity DNA binding.
Zhong, Min, Orosz, András, Wu, Carl
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Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease [PDF]
, 2008 Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (PrP). At present, the molecular pathways underlying prion-mediated neurotoxicity are largely unknown.
Aguzzi, Adriano +8 more
core +3 more sources
Heat shock transcription factor activates transcription of the yeast metallothionein gene. [PDF]
Molecular and Cellular Biology, 1991 In the yeast Saccharomyces cerevisiae, transcription of the metallothionein gene CUP1 is induced by copper and silver. Strains with a complete deletion of the ACE1 gene, the copper-dependent activator of CUP1 transcription, are hypersensitive to copper. These strains have a low but significant basal level of CUP1 transcription.
P, Silar, G, Butler, D J, Thiele
openaire +2 more sources
Identification and analysis of heat shock transcription factor gene in Zizania latifolia
浙江大学学报. 农业与生命科学版, 2023 To explore the function and potential applications of heat shock transcription factor (HSF) gene family on heat tolerance of Zizania latifolia of ‘Longjiao No. 2’, twenty-eight HSF proteins were identified and analyzed by bioinformatics methods.
CAI Licong +5 more
doaj +1 more source
Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. [PDF]
, 2017 BACKGROUND: Maintenance of cell fate determination requires the Polycomb group for repression; the trithorax group for gene activation; and the enhancer of trithorax and Polycomb (ETP) group for both repression and activation.
Brock, Hugh W +4 more
core +2 more sources
The Yeast and Mammalian Ras Pathways Control Transcription of Heat Shock Genes Independently of Heat Shock Transcription Factor [PDF]
Molecular and Cellular Biology, 1994 Yeast strains in which the Ras-cyclic AMP (cAMP) pathway is constitutively active are sensitive to heat shock, whereas mutants in which the activity of this pathway is low are hyperresistant to heat shock. To determine the molecular basis for these differences, we examined the transcriptional induction of heat shock genes in various yeast strains ...
Engelberg, D. +3 more
openaire +4 more sources