Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans [PDF]
, 2019 Target of rapamycin (TOR) signaling is an evolutionarily well-conserved pathway that regulates various physiologic processes, including aging and metabolism. One of the key downstream components of TOR signaling is ribosomal protein S6 kinase (S6K) whose
daeeun jeong +5 more
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Genome-wide transcriptional profiles during temperature and oxidative stress reveal coordinated expression patterns and overlapping regulons in rice. [PDF]
PLoS ONE, 2012 Genome wide transcriptional changes by cold stress, heat stress and oxidative stress in rice seedlings were analyzed. Heat stress resulted in predominant changes in transcripts of heat shock protein and heat shock transcription factor genes, as well as ...
Dheeraj Mittal +2 more
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Stress response in mesoangioblast stem cells [PDF]
, 2006 Stem cells are presumed to survive various stresses, since they are recruited to areas of tissue damage and regeneration, where inflammatory cytokines and cytotoxic cells may result in severe cell injury.
COSSU G +5 more
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Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation [PDF]
, 2013 Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-kappa B-mediated gene expression.
Bahar, Ali A +18 more
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An NMR Study on the clpC Operon Binding Region of Transcription Factor CtsR from Bacillus subtilis
Chinese Journal of Magnetic Resonance, 2021 When Gram-positive bacterium Bacillus subtilis responds to heat-shock, protein arginine kinase McsB phosphorylates Arg62 (R) in the clpC operon binding region of transcription factor CtsR, leading to dissociation of CtsR and clpC operon and initiation of
CHEN Xiao-wen +3 more
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Hopf bifurcation in a gene regulatory network model: Molecular movement causes oscillations [PDF]
, 2015 Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes.
Chaplain, M, Ptashnyk, M, Sturrock, M
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Interaction between the Circadian Clock and Regulators of Heat Stress Responses in Plants. [PDF]
, 2020 The circadian clock is found ubiquitously in nature, and helps organisms coordinate internal biological processes with environmental cues that inform the time of the day or year.
Bonnot, Titouan +2 more
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Heat Shock Factor 1 Is a Transcription Factor of Fas Gene
Molecules and Cells, 2010 In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat treatment effectively induced expression of Fas.
E, Shunmei +6 more
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Electronic Journal of Plant Breeding, 2020 In the present investigation, differential expression of two transcription factor genes (HsfA4d and HsfB2a) and a heat shock protein (ClpD1/HSP100) was evaluated in the rice varieties N22 and Co 51 using qRT-PCR.
Rishima Maheendran, V. Soundarrajan, N. M. Manikanda Boopathi, R. Gnanam, V. Geethalakshmi and P. Meenakshisundaram
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Cells, 2022 Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response.
Patryk Janus +8 more
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