Results 31 to 40 of about 134,612 (257)

Genome-wide transcriptional profiles during temperature and oxidative stress reveal coordinated expression patterns and overlapping regulons in rice. [PDF]

PLoS ONE, 2012
Genome wide transcriptional changes by cold stress, heat stress and oxidative stress in rice seedlings were analyzed. Heat stress resulted in predominant changes in transcripts of heat shock protein and heat shock transcription factor genes, as well as ...
Dheeraj Mittal, Dinesh A Madhyastha, Anil Grover   +2 more
doaj   +1 more source

Heat Shock Factor 1 Is a Transcription Factor of Fas Gene

Molecules and Cells, 2010
In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat treatment effectively induced expression of Fas.
E, Shunmei, Yuanbo, Zhao, Yunhong, Huang, Kun, Lai, Cha, Chen, Jianming, Zeng, Jiangying, Zou   +6 more
openaire   +2 more sources

An NMR Study on the clpC Operon Binding Region of Transcription Factor CtsR from Bacillus subtilis

Chinese Journal of Magnetic Resonance, 2021
When Gram-positive bacterium Bacillus subtilis responds to heat-shock, protein arginine kinase McsB phosphorylates Arg62 (R) in the clpC operon binding region of transcription factor CtsR, leading to dissociation of CtsR and clpC operon and initiation of
CHEN Xiao-wen, HUANG Bi-ling, HUANG Shao-hua, ZHAO Yu-fen   +3 more
doaj   +1 more source

HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes

Cells, 2022
Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is activated by proteotoxic agents and participates in the regulation of cellular stress response.
Patryk Janus, Paweł Kuś, Natalia Vydra, Agnieszka Toma-Jonik, Tomasz Stokowy, Katarzyna Mrowiec, Bartosz Wojtaś, Bartłomiej Gielniewski, Wiesława Widłak   +8 more
doaj   +1 more source

Role of Heat Shock Factors in Stress-Induced Transcription [PDF]

, 2017
Heat shock proteins (HSP) are rapidly induced after stresses such as heat shock and accumulate at high concentrations in cells. HSP induction involves primarily a family of heat shock transcription factors (HSF) that bind the heat shock elements of the HSP genes and mediate transcription in trans.
Ayesha, Murshid, Thomas L, Prince, Ben, Lang, Stuart K, Calderwood   +3 more
openaire   +2 more sources

The Role of Heat Shock Factors in Stress-Induced Transcription [PDF]

, 2011
Heat shock proteins (HSPs) are rapidly induced after stresses, such as heat shock, and accumulate at high concentrations in cells. HSP induction involves a family of heat shock transcription factors that bind the heat shock elements of the HSP genes and mediate transcription in trans. We discuss methods for the study of HSP binding to HSP promoters and
Yue, Zhang, Shiuh-Dih, Chou, Ayesha, Murshid, Thomas L, Prince, Sheila, Schreiner, Mary Ann, Stevenson, Stuart K, Calderwood   +6 more
openaire   +2 more sources

The Yeast and Mammalian Ras Pathways Control Transcription of Heat Shock Genes Independently of Heat Shock Transcription Factor [PDF]

Molecular and Cellular Biology, 1994
Yeast strains in which the Ras-cyclic AMP (cAMP) pathway is constitutively active are sensitive to heat shock, whereas mutants in which the activity of this pathway is low are hyperresistant to heat shock. To determine the molecular basis for these differences, we examined the transcriptional induction of heat shock genes in various yeast strains ...
Engelberg, D., Zandi, E., Parker, C. S., Karin, M.   +3 more
openaire   +4 more sources

Direct Sensing of Heat and Oxidation by Drosophila Heat Shock Transcription Factor [PDF]

Molecular Cell, 1998
The heat shock transcription factor HSF activates expression of its target genes in response to elevated temperatures and chemical or physiological stress. A key step in the activation process involves the formation of HSF homotrimers, leading to high-affinity DNA binding.
Zhong, Min, Orosz, András, Wu, Carl
openaire   +2 more sources

Heat shock transcription factor activates transcription of the yeast metallothionein gene. [PDF]

Molecular and Cellular Biology, 1991
In the yeast Saccharomyces cerevisiae, transcription of the metallothionein gene CUP1 is induced by copper and silver. Strains with a complete deletion of the ACE1 gene, the copper-dependent activator of CUP1 transcription, are hypersensitive to copper. These strains have a low but significant basal level of CUP1 transcription.
P, Silar, G, Butler, D J, Thiele
openaire   +2 more sources

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Nature Communications, 2016
The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in ...
Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen   +9 more
doaj   +1 more source