Results 31 to 40 of about 114,209 (360)
Animals, 2020 This study aimed to analyze the admission causes, outcomes, primary causes of death, and main lesions observed in the post mortem examinations of Western European hedgehogs, Erinaceus europaeus (Linnaeus, 1758), in the north of Portugal.
Andreia Garcês +6 more
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Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT
Science, 2021 How Hedgehog gets its lipid tail Phospholipid membranes serve as barriers between different cellular environments but are also crucial platforms for biosynthesis, signaling, and transport.
Yiyang Jiang, Thomas L. Benz, S. Long
semanticscholar +1 more source
Archives of Dermatology, 1999 Hedgehogs are increasingly popular pets in the United States and Europe. A number of infections may be acquired from these animals, and hedgehogs are possible hosts of parasites. However, to our knowledge there arc no previous reports of urticarial reactions to hedgehogs.We describe 3 patients who developed an acute, transient, urticarial reaction ...
J A, Fairley, J, Suchniak, A S, Paller
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The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
Bosnian Journal of Basic Medical Sciences, 2017 The Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. It is a highly conserved evolutionary pathway of signal transmission from the cell membrane to the nucleus.
Ana Marija Škoda +5 more
semanticscholar +1 more source
Primary Cilia and Mammalian Hedgehog Signaling.
Cold Spring Harbor Perspectives in Biology, 2017 It has been a decade since it was discovered that primary cilia have an essential role in Hedgehog (Hh) signaling in mammals. This discovery came from screens in the mouse that identified a set of genes that are required for both normal Hh signaling and ...
F. Bangs, K. Anderson
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Development, 2021 The mechanisms of vertebrate Hedgehog signaling are linked to the biology of the primary cilium, an antenna-like organelle that projects from the surface of most vertebrate cell types.
Emily K. Ho, T. Stearns
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Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling [PDF]
Nature Chemical Biology, 2013 Inhibition of Sonic hedgehog (Shh) signaling is of great clinical interest. Here we exploit Hedgehog acyltransferase (Hhat)-mediated Shh palmitoylation, a modification critical for Shh signaling, as a new target for Shh pathway inhibition. A target-oriented high-throughput screen was used to identify small-molecule inhibitors of Hhat.
Ouathek Ouerfelli +4 more
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Nature, 1921 IN NATURE of May 19 last (pp. 375–76) you were good enough to notice at length my paper on “The Ancient Legend as to the Hedgehog carrying Fruit upon its Spines,“ published by the Manchester Literary and Philosophical Society (Memoirs, vol. 63, No. 2). That paper was written with a view to elicit further evidence for or against the truth of the legend,
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Biochemical mechanisms of vertebrate hedgehog signaling
Development, 2019 Signaling pathways that mediate cell-cell communication are essential for collective cell behaviors in multicellular systems. The hedgehog (HH) pathway, first discovered and elucidated in Drosophila, is one of these iconic signaling systems that plays ...
Jennifer H. Kong, C. Siebold, R. Rohatgi
semanticscholar +1 more source
Frontiers in SustainabilityAirports, the essential hubs of global travel, have to cater for the increasing demands for air travel, with growing passenger numbers and the associated growth in resource consumption.
Anne van der Tuin-Rademaker +5 more
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