Results 31 to 40 of about 6,670 (185)

Complete analysis of the H5 hemagglutinin and N8 neuraminidase phylogenetic trees reveals that the H5N8 subtype has been produced by multiple reassortment events [PDF]

, 2016
The analysis of the complete H5 hemagglutinin and H8 neuraminidase phylogenetic trees presented in this paper shows that the H5N8 avian influenza has been generated by multiple reassortment events.
A Dalby, A Dalby, A Dalby, A Rambaut, C Adlhoch, D Alexander, D Lee, F Matsen, G Smith, H Ip, H Shimodaira, H Wu, H Yoon, J Brown, J Jeong, J Pasick, J Verhagen, K Ku, K Tamura, M Jhung, M Price, R Squires, X Xu, Y Bao, Y Lee   +24 more
core   +1 more source

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C., Ansaldi F., Calamusa G., Canepa P., Colomba G. M. E., Orsi A., Pojero F., Tramuto F., Trucchi C., Vitale F.   +9 more
core   +1 more source

Isolation of novel sequences targeting highly variable viral protein hemagglutinin

MethodsX, 2015
Rapid evolution is a hallmark of the viral kingdom and a major concern for developing universal vaccines. The isolation of substantial numbers of viral sequence variants at highly variable viral protein domains remains a major challenge. We previously developed a combinatorial method for the isolation of novel sequences to cope with rapid viral ...
Zhiwu Xu, Jieyu Wu, Fan Feng, Xiaoxiao Zhang, Xiaoqian Ma, Man Tang, Yan Huang, Ying Zhang, Yongchang Cao, Weiguo Cao, Ran He, Ye Gao, Qiuyun Liu   +12 more
openaire   +3 more sources

Oligomerization of bacterially expressed H1N1 recombinant hemagglutinin contributes to protection against viral challenge [PDF]

Scientific Reports, 2018
AbstractVaccination is the most effective intervention to prevent influenza and control the spread of the virus. Alternatives are needed to the traditional egg-based vaccine strategy for a more rapid response to new outbreaks. Two different hemagglutinin (HA) fragments (rHA11-326 and rHA153-269) derived from influenza A virus subtype H1N1 were ...
Kuenstling, Tess E., Sambol, Anthony R., Hinrichs, Steven H., Larson, Marilynn A.   +3 more
openaire   +3 more sources

Natural Cytotoxicity Receptors: Pattern Recognition and Involvement of Carbohydrates

The Scientific World Journal, 2005
Natural cytotoxicity receptors (NCRs), expressed by natural killer (NK) cells, trigger NK lysis of tumor and virus-infected cells on interaction with cell-surface ligands of these target cells.
Angel Porgador
doaj   +1 more source

Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]

, 2008
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core   +3 more sources

Glycans as receptors for influenza pathogenesis [PDF]

, 2010
Influenza A viruses, members of the Orthomyxoviridae family, are responsible for annual seasonal influenza epidemics and occasional global pandemics.
A Chandrasekaran, A Gambaryan, A Gottschalk, A Srinivasan, A Varki, Aarthi Chandrasekaran, Aravind Srinivasan, AS Gambaryan, AS Gambaryan, AS Gambaryan, AS Gambaryan, C Basler, C Traving, CA Bewley, CW Lee, DA Steinhauer, DC Nguyen, DC Wiley, E Klenk, F Zilliken, G Neumann, GK Hirst, GN Rogers, HL Yen, IA Wilson, J Stevens, J Stevens, JC Paulson, JJ Skehel, JK Taubenberger, JM Nicholls, K Kumari, K Shinya, Karthik Viswanathan, LA Perrone, LG Baum, M Bernfield, M Matrosovich, M Matrosovich, M Matrosovich, MB Eisen, MD Jong de, MI Nelson, NM Varki, O Blixt, O Blixt, P Bohm, P Palese, PH Seeberger, R Raman, R Raman, R Sasisekharan, Rahul Raman, Ram Sasisekharan, RJ Connor, RJ Russell, RJ Russell, RL Chen, S Hanson, S Yamada, SJ Gamblin, T Ito, T Kuiken, TH Tran, TM Tumpey, TM Tumpey, TM Tumpey, TM Tumpey, TR Maines, TR Maines, V. Sasisekharan, X Song, Y Ha, Y Ha, Y Suzuki, ZY Yang   +75 more
core   +1 more source

Recognition of viral hemagglutinins by NKp44 but not by NKp30

European Journal of Immunology, 2001
Natural killer (NK) cells destroy virus-infected and tumor cells without prior antigen stimulation. The NK cell cytotoxicity is regulated in large part by the expression of NK cell receptors that are able to bind major histocompatibility complex (MHC) class I glycoproteins.
Arnon, T, Lev, M, Katz, G, Chernobrov, Y, Porgador, A, Mandelboim, O   +5 more
openaire   +3 more sources

Structural Basis for Influence of Viral Glycans on Ligand Binding by Influenza Hemagglutinin [PDF]

Biophysical Journal, 2008
Binding of cell surface glycans by influenza hemagglutinin controls viral attachment and infection of host cells. This binding is a three-way interaction between viral proteins, host glycans, and viral glycans; many structural details of this interaction have been difficult to resolve.
Kasson, Peter M., Pande, Vijay S.
openaire   +2 more sources

Highly sensitive detection of influenza virus with SERS aptasensor.

PLoS ONE, 2019
Highly sensitive and rapid technology of surface enhanced Raman scattering (SERS) was applied to create aptasensors for influenza virus detection. SERS achieves 106-109 times signal amplification, yielding excellent sensitivity, whereas aptamers to ...
Vladimir I Kukushkin, Nikita M Ivanov, Anastasia A Novoseltseva, Alexandra S Gambaryan, Igor V Yaminsky, Alexey M Kopylov, Elena G Zavyalova   +6 more
doaj   +1 more source