Results 251 to 260 of about 416,052 (359)

Hematopoietic Stem Cell Transplantation for Treatment of Myleodysplastic Syndromes

, 2010
Richard Champlin
openalex   +1 more source

Additional file 1 of MSX2 suppression through inhibition of TGFβ signaling enhances hematopoietic differentiation of human embryonic stem cells

, 2020
Hongtao Wang, Mengge Wang, Yu Wang, Yuqi Wen, Xiaohong Chen, Dan Wu, Pei Su, Wen Zhou, Lihong Shi, Jiaxi Zhou   +9 more
openalex   +1 more source

CXC Chemokine‐Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response

Advanced Science, EarlyView.
Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen, Yinde Huang, Juntong Wu, Ziying Yi, Yao Li, Zeyu Yang, Fan Zhang, Chong Li   +7 more
wiley   +1 more source

Protocol for the isolation and characterization of mouse alveolar bone marrow hematopoietic stem cells. [PDF]

STAR Protoc
Niizuma K, Morikawa S, Gars E, Chang AH, Wilkinson AC, Nakauchi H, Yamamoto R.   +6 more
europepmc   +1 more source

Hematopoietic stem cells are increased by Cyp2c44 gene deletion: Implication in chronic hypoxia-induced pulmonary hypertension in mice

, 2017
Hashimoto Ryota, Joshi Sachindra Raj, Houli Jiang, Capdevila Jorge, Schwartzman Michel L, Gupte Sachin A   +5 more
openalex   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

CD99 promotes self-renewal in hematopoietic stem cells and leukemia stem cells by regulating protein synthesis.

Blood
Ji Y, Huang Y, Thomas T, Gozel Kapti E, Tachibana R, Lark J, Berezniuk I, Guo L, Ali MAE, Mims K, Kroger B, Hu W, Park CY, Chung SS.   +13 more
europepmc   +1 more source

Clonal evolution of hematopoietic stem cells after autologous stem cell transplantation. [PDF]

Nat Genet
Uryu H, Saeki K, Haeno H, Kapadia CD, Furudate K, Nangalia J, Spencer Chapman M, Zhang L, Padilla J, Zhao L, Hsu JI, Zhao C, Chen S, Tanaka T, Li Z, Ogata S, Hanache S, Yang H, DiNardo C, Daver N, Pemmaraju N, Jain N, Ravandi F, Zhang J, Song X, Thompson E, Tang H, Little L, Gumbs C, Orlowski RZ, Qazilbash M, Bhalla K, Colla S, Kantarjian H, Kanagal-Shamanna R, Bueso-Ramos C, Nakada D, Al-Atrash G, Molldrem J, Futreal PA, Shpall E, Goodell M, Garcia-Manero G, Takahashi K.   +43 more
europepmc   +1 more source

Impact of Injection Volume and Infusion Rate in a Large Animal Model Designed to Optimize intrabone Transplantation of Hematopoietic Stem Cells

, 2011
Jeremy Pantin, Holdcraft Robert, M.Y. Chen, Henry Timothy, Clare Randall, Richard Childs   +5 more
openalex   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source