Results 121 to 130 of about 11,782 (206)
Contrast Agents for Enhanced Bioimaging: A Comprehensive Review
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube +17 more
wiley +1 more source
Heme Protein Biogenesis - Catalase in Enterococcus faecalis [PDF]
Heme proteins form a large and diverse group of proteins which are involved in a variety of biological functions. The heme prosthetic group enables them to carry out redox reactions, transport electrons, bind gaseous molecules, and function as sensors ...
Baureder, Michael
core
TMEM14C is required for erythroid mitochondrial heme metabolism [PDF]
The transport and intracellular trafficking of heme biosynthesis intermediates are crucial for hemoglobin production, which is a critical process in developing red cells.
Lodish H. F. +34 more
core +1 more source
Loss of the putative Rab GTPase, Ypt7, impairs the virulence of Cryptococcus neoformans
Small GTPases of the Rab family coordinate multiple membrane fusion and trafficking events in eukaryotes. In fungi, the Rab GTPase, Ypt7, plays a critical role in late endosomal trafficking, and is required for homotypic fusion events in vacuole ...
Guanggan Hu +11 more
doaj +1 more source
Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen +2 more
wiley +1 more source
NDRG1 suppresses pancreatic cancer progression by disrupting small extracellular vesicle biogenesis, altering cargo composition, and inhibiting EV uptake by cancer cells—thereby impairing tumour–stroma communication and fibrotic activation. This study reveals NDRG1 as a novel regulator of extracellular vesicle dynamics and a promising therapeutic ...
Jiawei Chang +8 more
wiley +1 more source
Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages
Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled liberation of iron. Many efforts have been made to understand heme trafficking inside macrophages,
Inês B. Santarino, Otília V. Vieira
doaj +1 more source
Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source
Abstract CYP2J2 is a membrane‐bound cytochrome P450 that is expressed in cardiomyocytes, where it is known to metabolize arachidonic acid into cardioprotective epoxyeicosatrienoic acids (EETs). It consists of transmembrane domains embedded in the hydrophobic segments of the cell membrane and surrounded by various lipids.
Rajatabha Das +3 more
wiley +1 more source
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández +5 more
wiley +1 more source

