Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
学位記番号 ...
Osawa, Sho+2 more
core
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT+28 more
core +1 more source
Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan+10 more
wiley +1 more source
Divergent Synthesis of Heparan Sulfate Oligosaccharides [PDF]
Heparan sulfates are implicated in a wide range of biological processes. A major challenge in deciphering their structure and activity relationship is the synthetic difficulties to access diverse heparan sulfate oligosaccharides with well-defined sulfation patterns. In order to expedite the synthesis, a divergent synthetic strategy was developed.
Peng Wang+10 more
openaire +2 more sources
Three representative WOx nanostructures, nanodot, nanowire, and nanosheet, have been bottom‐up synthesized to investigate the “structure‐function” correlations in the AKI treatment, the results of which demonstrated that nanosheet is the most promising candidate for AKI management among three geometries because of its intrinsic renal accumulation, long‐
Yi Wang+11 more
wiley +1 more source
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. [PDF]
Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Dykstra, Andrew B+2 more
core +2 more sources
The power of time‐of‐flight secondary ion mass spectrometry‐partial least square regression to detect interleukin‐8, a chemokine involved in inflammation and cancer, down to mass fractions of 1 ppm within biopolymer matrices, including Matrigel and glycosaminoglycan‐based hydrogels, is demonstrated.
Ralf Zimmermann+4 more
wiley +1 more source
Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj +1 more source
Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane [PDF]
Despite being engineered to avoid renal clearance, many cationic polymer (polycation)-based siRNA nanoparticles that are used for systemic delivery are rapidly eliminated from the circulation.
Andrews+26 more
core +3 more sources