Results 101 to 110 of about 84,900 (313)
Advanced Science, EarlyView.Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang +8 more
wiley +1 more source
Heparan sulfates and heparins: similar compounds performing the same functions in vertebrates and invertebrates? [PDF]
Brazilian Journal of Medical and Biological Research, 1999 The distribution and structure of heparan sulfate and heparin are briefly reviewed. Heparan sulfate is a ubiquitous compound of animal cells whose structure has been maintained throughout evolution, showing an enormous variability regarding the relative ...
H.B. Nader +14 more
doaj +1 more source
Heparanase and macrophage interplay in the onset of liver fibrosis [PDF]
, 2017 The heparan sulfate endoglycosidase heparanase (HPSE) is involved in tumor growth, chronic inflammation and fibrosis. Since a role for HPSE in chronic liver disease has not been demonstrated to date, the current study was aimed at investigating the ...
Crescenzi, Marika +5 more
core +2 more sources
Heparan sulfate as a regulator of inflammation and immunity [PDF]
Journal of Leukocyte Biology, 2018 Abstract Heparan sulfate is found on the surface of most cell types, as well as in basement membranes and extracellular matrices. Its strong anionic properties and highly variable structure enable this glycosaminoglycan to provide binding sites for numerous protein ligands, including many soluble mediators of the immune system, and may ...
Collins, L, Troeberg, L
openaire +6 more sources
Peptide Electrostatic Modulation Directs Human Neural Cell Fate
Advanced Science, EarlyView.This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos +10 more
wiley +1 more source
Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
, 2019 学位記番号 ...
Osawa, Sho +2 more
core
Divergent Synthesis of Heparan Sulfate Oligosaccharides [PDF]
The Journal of Organic Chemistry, 2015 Heparan sulfates are implicated in a wide range of biological processes. A major challenge in deciphering their structure and activity relationship is the synthetic difficulties to access diverse heparan sulfate oligosaccharides with well-defined sulfation patterns. In order to expedite the synthesis, a divergent synthetic strategy was developed.
Peng Wang +10 more
openaire +2 more sources
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
Advanced Science, EarlyView.This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Exit of Plasmodium Sporozoites from Oocysts Is an Active Process That Involves the Circumsporozoite Protein [PDF]
, 2005 Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands.
Fujioka, Hisashi +2 more
core +4 more sources