Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
eFood, Volume 7, Issue 3, June 2026.Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
Heparan sulfate as an attachment factor for ASFV is restricted by host HB-EGF. [PDF]
Cell Mol Life SciXue W +11 more
europepmc +1 more source
Decoding the Factor H‐Related Proteins: Gatekeepers of Complement Dysregulation in AMD
European Journal of Immunology, Volume 56, Issue 6, June 2026.This review will explore the role of the factor H‐related (FHR) proteins in age‐related macular degeneration (AMD), their accumulation in the outer blood/retinal barrier, and how they may contribute to barrier dysfunction and inflammation. ABSTRACT Age‐related macular degeneration (AMD) is the third most common form of blindness in the Western world ...
Jiaqi Tang +2 more
wiley +1 more source
Marine sulfated glycan inhibits tau-heparan sulfate interaction and tau cellular uptake. [PDF]
Int J Biol MacromolJones K +6 more
europepmc +1 more source
From Cell Line to Fillet: A Review of Biological and Engineering Strategies in Cultivated Seafood
Food Bioengineering, Volume 5, Issue 2, Page 259-277, June 2026.Bottlenecks of the cultivated seafood industry are shown, and they prevent efficiency of key production stages. These include limited cell line availability, sustainable and cost‐effective media, adaption to suspension culture, sustainable cost‐effective and edible scaffolds, food regulatory approval and acceptance of genetic modified organisms (GMO ...
Angela Trace +3 more
wiley +1 more source
Synthesis, Structure, and Function of Heparan Sulfate Glycopolymers to Investigate Glycosaminoglycan-Protein Interactions. [PDF]
Acc Chem ResSingh K +3 more
europepmc +1 more source
Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad +4 more
wiley +1 more source
Halofuginone suppresses hepcidin by a heparan sulfate-dependent mechanism to treat iron disorders in mice. [PDF]
Blood AdvLeal S +16 more
europepmc +1 more source
iNew Medicine, Volume 2, Issue 2, June 2026.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
N-Sulfated Heparan Sulfate Promotes Reelin Signaling as a Co-receptor. [PDF]
J Am Chem SocPan L +12 more
europepmc +1 more source