Results 161 to 170 of about 211,407 (207)
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.Integrative single‐cell multi‐omics analysis reveals molecular heterogeneity among piriform cortex principal neurons and identifies Reln+ superficial‐layer neurons as a selectively vulnerable population in Alzheimer's disease. Cross‐region comparison with entorhinal cortex layer II neurons reveals a shared Gpc5‐high/Sort1‐low vulnerability‐associated ...
Jiayue Meng +9 more
wiley +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.ABSTRACT This study investigated long‐term cognitive development and genotype–phenotype relationships in patients with Mucopolysaccharidosis Type II (MPS II). A nationwide prospective cohort study was conducted in the Netherlands with cognitive follow‐up since 2007.
J. (Julia) Holdorp +10 more
wiley +1 more source
JIMD Reports, Volume 67, Issue 5, September 2026.ABSTRACT Mucopolysaccharidosis Type I (MPS I) is a rare lysosomal storage disorder caused by α‐l‐iduronidase deficiency, leading to glycosaminoglycan accumulation and multisystem involvement. Wolf–Hirschhorn Syndrome (WHS) is a chromosomal disorder characterized by growth delay, dysmorphism, and developmental impairment.
Karla Cifuentes‐Uribe +4 more
wiley +1 more source
Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley +1 more source
My Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award
JOR SPINE, Volume 9, Issue 3, September 2026.ABSTRACT The intervertebral disc is a prime example of tissue adaptation to metabolic and mechanical extremes. As the largest avascular organ in the human body, the disc and the central nucleus pulposus (NP) endure constant compressive loading while sustaining a hypoxic, relatively acidic, and hyperosmotic microenvironment that would be inhospitable to
Makarand V. Risbud
wiley +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
MedComm, Volume 7, Issue 9, September 2026.The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Biosynthesis of Heparin and Heparan Sulfate [PDF]
Upsala Journal of Medical Sciences, 1977 openaire +2 more sources
MedComm – Oncology, Volume 5, Issue 3, September 2026.This review provides a comprehensive overview of carbon dot–based technologies for breast cancer diagnosis and therapy, including their toxicity profiles. It outlines how C‐dots function as a versatile platform—serving simultaneously as therapeutic agents, drug‐delivery vehicles, and bioimaging tools. The article also highlights cutting‐edge approaches
Srija Sur, Pegah Varamini
wiley +1 more source
Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights
Reviews in Medical Virology, Volume 36, Issue 5, September 2026.ABSTRACT Human cytomegalovirus (HCMV) is a globally prevalent virus that poses a significant public health concern, especially for newborns and immunocompromised patients, causing a wide range of infections. Clinical outcomes associated with HCMV infection include congenital disease, graft rejection in transplant recipients, and life‐threatening ...
Hajar Y. AlQahtani +2 more
wiley +1 more source