Results 201 to 210 of about 84,900 (313)

Metal-Mediated Il-8 Binding to Heparan Sulfate Evaluated by Electrochemical Impedance Spectroscopy. [PDF]

Chemistry
Shitrit A, Alshanski I, Mor K, Rademann J, Kikkeri R, Hurevich M, Yitzchaik S.   +6 more
europepmc   +1 more source

D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis

Advanced Science, Volume 12, Issue 40, October 27, 2025.
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing, Jun Wu, Jingru Ning, Xiaoyu Ding, Zhenyun Du, Xiaojiang Wang, Lulin Huang, Ran Wang, Changlin Mei, Kan Ding   +9 more
wiley   +1 more source

Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor.

, 1992
Alan D. Murdoch, George R. Dodge, I. Cohen, Rocky S. Tuan, Renato V. Iozzo   +4 more
openalex   +1 more source

Adipocyte heparan sulfate determines type 2 diabetes susceptibility in mice via FGF1-Mediated glucose regulation. [PDF]

Mol Metab
Yu CJ, Pessentheiner AR, Liu S, Wax S, Maciej-Hulme ML, Painter CD, Ramms B, Sandoval DR, Quach A, DeForest N, Ducasa GM, Tognaccini C, Labib C, Al-Azzam N, Haumann F, Trieger G, Secrest P, Majithia A, Petrey AC, Godula K, Atkins AR, Downes M, Evans RM, Gordts PLSM.   +23 more
europepmc   +1 more source

Extracellular LCN2 Binding to 24p3R in Astrocytes Impedes α‐Synuclein Endocytosis in Parkinson's Disease

Advanced Science, Volume 12, Issue 39, October 20, 2025.
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao, Tian Tian, Zhu Zhu, Lei Cao, Yang Liu, Rui‐An Wang, Zhi‐Yong Zhou, Cong Wang, Ke‐Zhong Zhang, Xiao Lu, Wen‐Wei Yun, Ying‐Mei Lu, Gang Hu, Ren‐Hong Du, Ming Lu   +14 more
wiley   +1 more source

Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.

, 1994
Masato Kato, H Wang, Merton Bernfield, J. T. Gallagher, Jeremy E. Turnbull   +4 more
openalex   +1 more source

Purification and Characterization of Heparan Sulfate 2-Sulfotransferase from Cultured Chinese Hamster Ovary Cells [PDF]

, 1996
Masashi Kobayashi, Hiroko Habuchi, Osami Habuchi, Masaki Saito, Koji Kimata   +4 more
openalex   +1 more source

The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Clinical discovery and the proposed underlying mechanism by how P. johnsonii ameliorated metabolic disorders. Abstract The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. However, the role of Parabacteroides johnsonii in metabolic disorders is never reported.
Yimeng Chen, Shujun Jiang, Haolu Wang, Mengzhen Si, Haixia Wu, Xinyi Liang, Shenmeng Yao, Yanliang Zhang, Xiaodong Wen, Jie Yang   +9 more
wiley   +1 more source

Basic fibroblast growth factor is internalized through both receptor-mediated and heparan sulfate-mediated mechanisms.

, 1992
Monireh Roghani, David Moscatelli
openalex   +1 more source

Segments in the C-terminal Folding Domain of Lipoprotein Lipase Important for Binding to the Low Density Lipoprotein Receptor-related Protein and to Heparan Sulfate Proteoglycans [PDF]

, 1997
Morten S. Nielsen, Jeanette Brejning, Raquel Garcı́a, Hanfang Zhang, Michael R. Hayden, Senén Vilaró, Jørgen Gliemann   +6 more
openalex   +1 more source