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Structure and Function of the Heparan Sulfate Proteoglycans [PDF]
, 1989 Heparan sulfate proteoglycans are a complex and heterogeneous family of macromolecules. They are composed of linear sulfated polysaccharide chains, the heparan sulfate moieties, that are covalently attached to protein. Their distribution is nearly ubiquitous.
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Autoantibodies to heparan sulfate proteoglycans
Autoimmunity Reviews, 2002Maryvonne Dueymes +4 more
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Heparan Sulfate Proteoglycans in Cancer Therapy
2011The polyanionic linear polysaccharide heparan sulfate specifically interacts with a multitude of extracellular ligands relevant to all steps of tumor progression. Heparan sulfate proteoglycans act as coreceptors for cytokine and chemokine signaling, modulating tumor cell growth and survival, chemotaxis, and angiogenesis.
Martin Götte +2 more
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BIOLOGICAL SIGNIFICANCE OF HEPARAN SULFATE PROTEOGLYCANS*
Annals of the New York Academy of Sciences, 1982P. Colburn, V. Buonassisi
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Proteoglycans as Mediators of Cancer Tissue Mechanics
Frontiers in Cell and Developmental Biology, 2020Alexander Buffone +2 more
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Heparan Sulfate Proteoglycans in Central Synapses [PDF]
, 2014 Yu Yamaguchi, Fumitoshi Irie
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Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
Journal of Cellular and Molecular Medicine, 2011Renato V Iozzo +2 more
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Basement membrane proteoglycans: from cellar to ceiling
Nature Reviews Molecular Cell Biology, 2005Renato V Iozzo
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Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and Cancer
F1000Research, 2016John R Couchman, Ralph D Sanderson
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