Complex Interactions Between Sex and Stress on Heroin Seeking
Frontiers in Neuroscience, 2021 Rationale: Stress plays a dual role in substance use disorders as a precursor to drug intake and a relapse precipitant. With heroin use at epidemic proportions in the United States, understanding interactions between stress disorders and opioid use ...
Jordan S. Carter +2 more
doaj +1 more source
Upregulation of SOCS-3 and PIAS-3 impairs IL-12-mediated interferon-gamma response in CD56 T cells in HCV-infected heroin users. [PDF]
PLoS ONE, 2010 CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use
Li Ye +5 more
doaj +1 more source
Swiss Medical Weekly, 2003 We report on a series of patients with acute strabismus related to heroin and methadone intake or withdrawal, discuss possible mechanisms involved in this clinical picture and make recommendations for work-up and referral.Retrospective study.Five patients presented with acute esotropia within days of heroin withdrawal, and two patients developed ...
Klara Landau, Florian K. P. Sutter
openaire +3 more sources
Toots, tastes and tester shots: user accounts of drug sampling methods for gauging heroin potency
Harm Reduction Journal, 2018 Background Internationally, overdose is the primary cause of death among people injecting drugs. However, since 2001, heroin-related overdose deaths in the United States (US) have risen sixfold, paralleled by a rise in the death rate attributed to ...
Sarah G. Mars +2 more
doaj +1 more source
The societal cost of heroin use disorder in the United States. [PDF]
PLoS ONE, 2017 Heroin use in the United States has reached epidemic proportions. The objective of this paper is to estimate the annual societal cost of heroin use disorder in the United States in 2015 US dollars.An analytic model was created that included incarceration
Ruixuan Jiang +3 more
doaj +1 more source
Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]
, 2018 The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J. +6 more
core +5 more sources
Heroin-piracetam mixture: suggested mechanisms of action and risks of misinterpretation for drug users [PDF]
, 2017 Piracetam is a positive allosteric modulator of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor that has been frequently used in the treatment of cognitive disorders.
Cappelletti, Simone +4 more
core +1 more source
Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]
, 2015 Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro +3 more
core +1 more source
Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]
, 1998 The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J. +9 more
core +1 more source
No evidence of accelerated epigenetic aging among black heroin users: A case vs control analysis
Addiction Neuroscience, 2023 This study sought to assess the association between illicit opioid use and accelerated epigenetic aging (A.K.A. DNAm Age) among people of African ancestry who use heroin.
Jermaine D. Jones +4 more
doaj +1 more source