Results 11 to 20 of about 100,982 (338)
Pharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in rats. [PDF]
PLoS ONE, 2014 The purpose of this study was to evaluate the effects of a morphine-conjugate vaccine (M-KLH) on the acquisition, maintenance, and reinstatement of heroin self-administration (HSA) in rats, and on heroin and metabolite distribution during heroin ...
Michael D Raleigh +2 more
doaj +1 more source
Harm Reduction Journal, 2022 Background Heroin pipe distribution may encourage people who use heroin (PWUH) to transition from injecting to smoking heroin, reducing harms associated with injection drug use.
Thomas Fitzpatrick +6 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Exposure to a heroin-associated conditioned stimulus can reactivate drug reward memory, trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region related to emotions and motivation, is involved in processing rewarding ...
Yuanyang Xie +10 more
doaj +1 more source
Hostility, compassion and role reversal in West Virginia’s long opioid overdose emergency
Harm Reduction Journal, 2020 Background West Virginia is a largely rural state with strong ties of kinship, mutual systems of support and charitable giving. At the same time, wealth inequalities are extreme and the state’s drug overdose fatality rate stands above all others in the ...
Jeff Ondocsin +3 more
doaj +1 more source
Cognitive Enhancer Donepezil Attenuates Heroin-Seeking Behavior Induced by Cues in Rats
Journal of Integrative Neuroscience, 2023 Purpose: Opioid use disorder is a significant global problem. Chronic heroin use is associated with impairment of cognitive function and conscious control ability.
Disen Mei +7 more
doaj +1 more source
BMJ, 1989 Sur 13 echantillons d'heroine saisis provenant de pays tropicaux, 4 contiennent de l'aflatoxine B 1 . Des aflatoxines sont decelees dans l'urine de 27 toxicomanes sur 133. L'attention est attiree sur ce nouveau risque d'infection (hepatite, sida) chez les toxicomanes utilisant des injections intra-veineuses, l'aflatoxines ayant des proprietes ...
R. Young +2 more
openaire +3 more sources
Complex Interactions Between Sex and Stress on Heroin Seeking
Frontiers in Neuroscience, 2021 Rationale: Stress plays a dual role in substance use disorders as a precursor to drug intake and a relapse precipitant. With heroin use at epidemic proportions in the United States, understanding interactions between stress disorders and opioid use ...
Jordan S. Carter +2 more
doaj +1 more source
Upregulation of SOCS-3 and PIAS-3 impairs IL-12-mediated interferon-gamma response in CD56 T cells in HCV-infected heroin users. [PDF]
PLoS ONE, 2010 CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use
Li Ye +5 more
doaj +1 more source
Swiss Medical Weekly, 2003 We report on a series of patients with acute strabismus related to heroin and methadone intake or withdrawal, discuss possible mechanisms involved in this clinical picture and make recommendations for work-up and referral.Retrospective study.Five patients presented with acute esotropia within days of heroin withdrawal, and two patients developed ...
Klara Landau, Florian K. P. Sutter
openaire +3 more sources
Reported Heroin Use, Use Disorder, and Injection Among Adults in the United States, 2002-2018.
Journal of the American Medical Association (JAMA), 2020 This study uses National Surveys on Drug Use and Health data to characterize trends in heroin use, heroin use disorder, and heroin injection overall and by age, race, and geographic region.
B. Han +3 more
semanticscholar +1 more source