Results 31 to 40 of about 58,740 (306)

Characterization of hexokinase gene family members in Glycine max and functional analysis of GmHXK2 under salt stress

open access: yesFrontiers in Genetics, 2023
Hexokinase (HXK) is a bifunctional enzyme involved in carbohydrate metabolism and sugar signal sensing. HXK gene family has been extensively discussed in many species, while the detailed investigations of the family in Glycine max have yet to be reported.
Shuai Chen, Zengyuan Tian, Yuqi Guo
doaj   +1 more source

Is hexokinase really a sugar sensor in plants?

open access: yes, 1999
The molecular mechanisms by which plant cells sense sugar levels are not understood, but current models (adapted from models for sugar sensing in yeast) favour hexokinase as the primary sugar sensor.
Purcell, P. C.   +2 more
core   +1 more source

Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production

open access: yesEMBO Molecular Medicine, 2012
Hexokinase‐II (HKII) is highly expressed in the heart and can bind to the mitochondrial outer membrane. Since cardiac hypertrophy is associated with a substrate switch from fatty acid to glucose, we hypothesized that a reduction in HKII would decrease ...
Rongxue Wu   +7 more
doaj   +1 more source

Hexokinase 2

open access: yes, 2015
Hexokinase II (also known as HK II) is an enzyme encoded by the HK II gene, located in human chromosome band 2p13. The protein product of the HK II gene is a hexokinase. HK II is a member of the hexokinase family.
Shuai Jiang, Jiang, Shuai
core   +1 more source

All hexokinase isoenzymes coexist in rat hepatocytes [PDF]

open access: yes, 1984
The cellular distribution of hexokinase isoenzymes, N-acetylglucosaminase kinase and pyruvate kinases in rat liver was studied. Hepatocytes and non-parenchymal cells with high viability and almost no cross-contamination were obtained by perfusion in situ
Cardenas,, Reyes,
core   +1 more source

First mutation in the red blood cell-specific promoter of hexokinase combined with a novel missense mutation causes hexokinase deficiency and mild chronic hemolysis

open access: yesHaematologica, 2009
Background Hexokinase is one of the key enzymes of glycolysis and catalyzes the phosphorylation of glucose to glucose-6-phosphate. Red blood cell-specific hexokinase is transcribed from HK1 by use of an erythroid-specific promoter.
Karen M.K. de Vooght   +4 more
doaj   +1 more source

Activators of Yeast Hexokinase

open access: yesJournal of Biological Chemistry, 1971
Abstract The rate of the ATP:glucose transphosphorylase reaction catalyzed by yeast hexokinase, isozyme Pii, is inhibited by lowering the pH of the reaction below 7.0, especially at suboptimal concentrations of ATP. This effect of acidity is largely overcome by activators such as orthophosphate, citrate, malate, 3-phosphoglycerate, and riboside ...
D P, Kosow, I A, Rose
openaire   +2 more sources

The invasive cell coat at the microsporidian Trachipleistophora hominis–host cell interface contains secreted hexokinases

open access: yesMicrobiologyOpen, 2019
Microsporidia are obligate intracellular parasites causing significant disease in humans and economically important animals. In parallel to their extreme genetic reduction, Microsporidia have evolved novel mechanisms for exploiting host metabolism.
Sophie Ferguson, John Lucocq
doaj   +1 more source

Effect of aluminum toxicity and Bacopa monnieri on hexokinase enzyme activity in Wistar albino rats

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Aluminum enters human body through food and drinking, cosmetics, and occupational exposures. Aluminum (Al) is a highly neurotoxic element causes neuronal degeneration in humans as well as in animals.
Vasanthan S, Prabal Joshi
doaj   +1 more source

Intracellular distribution of hexokinase in rabbit brain

open access: yes, 1993
Hexokinase in mammalian brain is particulate and usually considered to be bound to the outer mitochondrial membrane. Investigation of rabbit brain mitochondria prepared either by differential centrifugation and discontinuous density gradient ...
SERAFINI G.   +5 more
core   +1 more source

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