Results 51 to 60 of about 59,802 (286)
Effects of Salicylic Acid on the Metabolism of Mitochondrial Reactive Oxygen Species in Plants
Biomolecules, 2020 Different abiotic and biotic stresses lead to the production and accumulation of reactive oxygen species (ROS) in various cell organelles such as in mitochondria, resulting in oxidative stress, inducing defense responses or programmed cell death (PCD) in
Péter Poór
doaj +1 more source
, 1998 Hexokinase I, the pacemaker of glycolysis in brain tissue and red blood cells, is comprised of two similar domains fused into a single polypeptide chain.
Honzatko, Richard B +4 more
core +1 more source
New insight into hexokinase-VDAC interactions in a fungal system [PDF]
, 2023 Hexokinase and VDAC are two critical proteins throughout fungi. Despite the considerable number of studies on VDAC-hexokinase interactions in animal systems, little research has been attempted looking at their interaction in fungal systems.
Dubyna, Jason
core
A Hexokinase Inhibitor in Nerve.
Experimental Biology and Medicine, 1951 Summary1. Nerve homogenates, but not those of muscle or liver, inhibit brain glycolysis, the inhibition being a linear function of the amount of nerve. 2. Two thirds of the inhibitor activity is in a protein and lipid fraction precipitated at pH 5.3 to pH 5.5. From 200 mg of fresh nerve, 3 mg of protein and a like amount of lipid are obtained.
L G, ABOOD, R W, GERARD
openaire +2 more sources
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
, 1995 Macromolecules can restore the morphological changes in the outer mitochondrial compartment that occur upon isolation of the organelle. They decrease the volume of the intermembrane space and increase the number of intermembrane contact sites.
Gellerich, F.N. +2 more
core +1 more source
Product Inhibition of the Hexokinases
Journal of Biological Chemistry, 1970 ADP3- and ADPMg caused mixed inhibition of purified yeast hexokinase isoenzymes and ascites tumor hexokinases I and II when ATPMg is the varied substrate. Since exchange between ADPMg and ATPMg is observed under steady state conditions in which free glucose-6-P is not available for reaction, the effect of ADPMg on Vmax must result from its reaction at ...
D P, Kosow, I A, Rose
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Advanced Science, EarlyView.In normal hepatocytes, FBP1 forms compartmentalized complexes with PKM2, ENO1, and LDHA independent of its catalytic activity, inhibiting PKM2 activity and restricting excessive glycolysis. During MASLD progression, FBP1 downregulation markedly reduces the abundance of these complexes and releases the “hijacked” glycolytic enzymes, leading to PKM2 ...
Busong Wang +10 more
wiley +1 more source
Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity
Frontiers in Immunology, 2017 At the beginning of the twentieth century, discoveries in cancer research began to elucidate the idiosyncratic metabolic proclivities of tumor cells (1).
Scott M. Seki +3 more
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Advanced Science, EarlyView.GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko +5 more
wiley +1 more source