Results 81 to 90 of about 151,161 (274)

Immunohistochemistry for HIF-1α and HIF-1β.

, 2015
HIF, Hypoxia inducible factorImmunohistochemistry for HIF-1α and HIF-1β.
Najla Fakhruddin (750404), Marwan El-Sabban (317103), Lamis Yehia (750403), Fouad Boulos (631067), Mark Jabbour (631068), Ziyad Mahfoud (15883)   +5 more
core   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Analysis of HIF-1α-expression.

, 2015
Protein analysis for HIF-1α shows significant increase of HIF-1α-expression in hippocampal tissue 6h after SAH (A+B) independent from type of technique (Location of ICP-probe is hallmarked (+)).
Anke Höllig (721267), Rolf Rossaint (237), Agnieszka Weinandy (721268), Mark Coburn (173161), Hans Clusmann (721270), Kay Nolte (721269)   +5 more
core   +1 more source

Age-Related Expression and Localization of HIF-1α and HIF-2α in Different Tissues of Yak

Oxygen
The yak (Bos grunniens), a unique bovine species that is endemic to the Qinghai–Tibet Plateau and adjacent mountainous regions, exhibits remarkable adaptations to chronic high-altitude hypoxia.
Qin Wu, Huan Yang, Junyu Chen, Zhixin Chai, Hongwen Zhao, Zhijuan Wu   +5 more
doaj   +1 more source

A regulatory feedback loop between HIF-1α and PIM2 in HepG2 cells. [PDF]

PLoS ONE, 2014
To survive under hypoxic conditions, cancer cells remodel glucose metabolism to support tumor progression. HIF transcription factor is essential for cellular response to hypoxia.
Zhenhai Yu, Xiaoping Zhao, Yingying Ge, Teng Zhang, Liangqian Huang, Xiang Zhou, Lei Xie, Jianjun Liu, Gang Huang   +8 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Prx1 regulates HIF-1α expression.

, 2013
A. 2H-11 cells were stimulated with 20 nM rPrx1. Total RNA was collected at various times after stimulation and qPCR was performed with HIF-1α specific primers.
Sandra O. Gollnick (297886), Jonah R. Riddell (297880), Patricia Maier (297882), Stephanie N. Sass (297884), Barbara A. Foster (255172), Michael T. Moser (297885)   +5 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

HIF-transcribed p53 chaperones HIF-1α

, 2019
Chronic hypoxia is associated with a variety of physiological conditions such as rheumatoid arthritis, ischemia/reperfusion injury, stroke, diabetic vasculopathy, epilepsy and cancer.
Pati, Uttam K., Carvalho, Carlos, Moreno, Eduardo, Madan, Esha, Chandaria, Aliya, Nagane, Masaki, Palma, Antonio M., Canas-Marques, Rita, Kuppusamy, Periannan, Tomás, Ana R., Gogna, Rajan, Parker, Taylor M., Beltran, Antonio, Peixoto, Maria L., Galzerano, Antonio, Cabral-Teixeira, Joaquim, Henriques, Vanessa, Selvendiran, Karuppaiyah, Pelham, Christopher J.   +18 more
core   +1 more source

New insights into the key role of HIF-1α in IL-10-producing B cells [PDF]

, 2018
Hypoxia-inducible factors (HIFs) are essential transcription factors for the cellular response to hypoxia. Expression and stabilization of HIFs can be triggered by hypoxia or by other factors under pathological stress such as inflammation and infection ...
Xianyi Meng, Aline Bozec
core   +1 more source