Results 141 to 150 of about 115,732 (260)

The impact of exercise on cognitive function and brain health across the lifespan: A systematic review

Ibrain, EarlyView.
This systematic review of 37 studies demonstrates that aerobic, resistance, and combined exercise enhance cognitive function and brain health across all ages. Exercise promotes neuroplasticity, upregulates brain‐derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF), and mitigates age‐related cognitive decline, establishing ...
Issam AbuQeis, Abeer Teeti, Amro Titi
wiley   +1 more source

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

A histone acetylation score for prognostic stratification and immunogenomic profiling in esophageal cancer. [PDF]

Discov Oncol
Fan C, Sun K, Feng Z, Zhang P, Yang X, Min X.   +5 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Role of histone acetylation in the regulation of CD36 and ANGPTL1 in esophageal squamous cell carcinoma. [PDF]

BMC Cancer
Baba AM, Shyanti RK, Hajam MA, Nissa N, Muzaffar M, Bashir T, Fida S, Abdullah M, Singh RP, Dar NA.   +9 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Epigenetic Factors in Pathogenesis of Retinoblastoma: DNA Methylation and Histone Acetylation. [PDF]

Curr Issues Mol Biol
Kiosis G, Skourtsidis K, Ioannou D, Tseriotis VS, Stergiou K, Akritidou F, Papamitsou T, Kourti M, Karachrysafi S.   +8 more
europepmc   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

The BRD4-nucleosome interaction is enhanced modestly and non-selectively by histone acetylation. [PDF]

Nucleic Acids Res
Lambrechts LS, Reid XJ, Kambanis L, Luong C, Kobakhidze E, Daners A, Zhong Y, Patel K, Franck CK, Sani HM, Taylor C, Low JKK, Payne RJ, Mackay JP.   +13 more
europepmc   +1 more source