Results 141 to 150 of about 182,599 (256)

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

The FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu, Yue Gao, Marcin Luzarowski, Elisabeth Seebach, Thomas Heitkamp, Michael Börsch, Thomas Ruppert, Katharina F. Kubatzky   +7 more
wiley   +1 more source

The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

, 2000
Steven B. McMahon, Marcelo A. Wood, Michael D. Cole   +2 more
openalex   +1 more source

The Histone Acetyltransferase, hGCN5, Interacts with and Acetylates the HIV Transactivator, Tat [PDF]

, 2001
Edwige Col, Cécile Caron, Daphné Seigneurin‐Berny, Jocelyne Gracia, Alain Favier, Saadi Khochbin   +5 more
openalex   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu, Juyun Zhang, Zhu Lin, Xubiao Meng   +3 more
wiley   +1 more source

Three Yeast Proteins Related to the Human Candidate Tumor Suppressor p33^ING1 Are Associated with Histone Acetyltransferase Activities

, 2000
Robbie Loewith, Maria Meijer, Susan P. Lees‐Miller, Karl Riabowol, Dallan Young   +4 more
openalex   +1 more source

TaSED interacts with TaSPA synergistically regulating SDS‐sedimentation volume in bread wheat

Journal of Integrative Plant Biology, EarlyView.
Wheat TaSED is a positive regulator of SDS‐sedimentation volume, an indicator of gluten strength and thus baking properties. TaSED interacts with the transcription factor TaSPA regulating wheat storage protein gene expression, altering protein composition and affecting SDS‐sedimentation volume, providing a valuable genetic resource for improving wheat ...
Shanshan Zhai, Runqi Zhang, Xinhao Meng, Guoyu Liu, Jiazheng Yu, Huanwen Xu, Hongyao Lou, Shidian Wen, Mingshan You, Chaojie Xie, Jie Liu, Zhongfu Ni, Qixin Sun, Baoyun Li   +13 more
wiley   +1 more source

Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

, 2000
Birgitte Ø. Wittschieben, Jane Fellows, Wendy Du, David J. Stillman, Jesper Q. Svejstrup   +4 more
openalex   +2 more sources

Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes [PDF]

, 2002
Ritu Pandey
openalex   +1 more source

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

Journal of Internal Medicine, EarlyView.
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley   +1 more source

Regulation of Global Acetylation in Mitosis through Loss of Histone Acetyltransferases and Deacetylases from Chromatin

, 2001
Michael J. Kruhlak, Michael J. Hendzel, Wolfgang Fischle, Nicholas Bertos, Shahid Hameed, Xiang-Jiao Yang, Eric Verdin, David P. Bazett‐Jones   +7 more
openalex   +1 more source