Results 171 to 180 of about 182,599 (256)
The Transcriptional Co-activators CREB-binding Protein (CBP) and p300 Play a Critical Role in Cardiac Hypertrophy That Is Dependent on Their Histone Acetyltransferase Activity [PDF]
, 2003 Rosalind Jane Gusterson +3 more
openalex +1 more source
FEBS Open Bio, Volume 15, Issue 6, Page 906-913, June 2025.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, Volume 12, Issue 21, June 5, 2025.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription [PDF]
, 2004 Kalipso Halkidou
openalex +1 more source
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury
Epigenetics, 2015 Jin Huang +5 more
semanticscholar +1 more source
Advanced Science, Volume 12, Issue 22, June 12, 2025.Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang +4 more
wiley +1 more source
E2F-Dependent Histone Acetylation and Recruitment of the Tip60 Acetyltransferase Complex to Chromatin in Late G1 [PDF]
, 2004 Stefan Taubert +7 more
openalex +1 more source
Advanced Science, Volume 12, Issue 21, June 5, 2025.MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun +13 more
wiley +1 more source
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 [PDF]
, 2004 Nevan J. Krogan +13 more
openalex +1 more source