Results 181 to 190 of about 42,139 (259)

Compact Cas12 Systems for Multiplex Engineering of Plant Abiotic‐Stress Networks

Advanced Genetics, Volume 7, Issue 2, June 2026.
ABSTRACT Compact CRISPR‐Cas12 platforms, particularly miniature and hypercompact effectors such as Cas12f, Cas12j/CasPhi, and Cas12lambda, are emerging as delivery‐efficient tools for plant genome engineering because their reduced coding size facilitates viral‐replicon and other size‐constrained delivery routes while supporting dense guide multiplexing.
Samar G. Thabet, Khairiah Mubarak Alwutayd, Amr Elkelish, Fatmah Ahmed Safhi, Mona F.A. Dawood, Ahmad M. Alqudah   +5 more
wiley   +1 more source

Arabidopsis histone acetyltransferase complex coordinates cytoplasmic histone acetylation and nuclear chromatin accessibility. [PDF]

Sci Adv
Wu CJ, Xu X, Yuan DY, Liu ZZ, Tan LM, Su YN, Li L, Chen S, He XJ.   +8 more
europepmc   +1 more source

The histone acetyltransferase CBP participates in regulating the DNA damage response through ATM after double-strand breaks. [PDF]

Genome Biol
Ramadan WS, Ahmed SBM, Talaat IM, Lozon L, Mouffak S, Gemoll T, Mansour WY, El-Awady R.   +7 more
europepmc   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

MYST2 histone acetyltransferase promotes lung adenocarcinoma progression by regulating the p38 MAPK signaling pathway. [PDF]

Transl Oncol
Huang Z, Zhang W, Wang P, Wu M, Guo Y, Chen J.   +5 more
europepmc   +1 more source

DNA Double-Strand Break Movement in Heterochromatin Depends on the Histone Acetyltransferase dGcn5

, 2023
Kendek A, Sandron A, Lambooij J, Colmenares SU, Pociunaite SM, Gooijers I, de Groot L, Karpen GH, Janssen A.   +8 more
europepmc   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

CitGATA7 interact with histone acetyltransferase CitHAG28 to promote citric acid degradation by regulating the glutamine synthetase pathway in citrus. [PDF]

Mol Hortic
Lin X, Li S, Shi Y, Ma Y, Li Y, Tan H, Zhang B, Xu C, Chen K.   +8 more
europepmc   +1 more source

The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 6, June 2026.
To define the mechanisms of sensitivity to PP2A inhibitors (PP2Ai), we combined molecular profiling of PP2Ai responses with genome‐wide genetic screens. PP2Ai preferentially target mesenchymal pancreatic ductal adenocarcinoma (PDAC) cells and engage pathways linked to transcriptional elongation, splicing, metabolism, and ER stress response factors ...
Janine Murr, Carolin Schneider, Ningjun Duan, Hazal Köse, Anantharamanan Rajamani, Xueyang He, Jonas Buchloh, Christian Hintze, Atharva Naik, Daniel Goeke, Nicole Rjasanow, Lukas Krauß, Alexandra Nguyen, Sebastian A. Widholz, Christian Schneeweis, Riccardo Trozzo, Felix Orben, Sebastian Mueller, Rupert Öllinger, Juan J Montero, Michael Dudek, Percy Knolle, Bo Kong, Volker Ellenrieder, Constanza Tapia Contreras, Elisabeth Hessmann, Marian Grade, Michael Ghadimi, Christian J. Braun, Roland Rad, Maximillian Reichert, Ulrich Keller, Roland M. Schmid, Paul L. Boutz, Dieter Saur, Matthias Wirth, Oliver H. Krämer, Günter Schneider   +37 more
wiley   +1 more source

DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5. [PDF]

Nucleic Acids Res
Kendek A, Sandron A, Lambooij JP, Colmenares SU, Pociunaite SM, Gooijers I, de Groot L, Karpen GH, Janssen A.   +8 more
europepmc   +1 more source