Results 181 to 190 of about 391,128 (337)

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

Plant, Cell &Environment, EarlyView.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee, Madhabi Das, Sanjib Patra, Srijib Chatterjee, Amit Roy, Arunava Mandal   +5 more
wiley   +1 more source

Inhibition of histone acetyltransferase KAT7 suppresses proliferation and migration of breast cancer cells. [PDF]

Front Oncol
Du W, Xiao X, Zhang J, Shi Z, Yang M.
europepmc   +1 more source

Deletion of a Histone Acetyltransferase Leads to the Pleiotropic Activation of Natural Products in Metarhizium robertsii.

Organic Letters, 2017
Ai-Li Fan, Wubin Mi, Zhiguo Liu, Guohong Zeng, Peng Zhang, Youcai Hu, Wei-Guo Fang, Wen-Bing Yin   +7 more
semanticscholar   +1 more source

Histone variants and histone exchange

, 2006
Histories, as basic components of nucleosome. are essential to chromatin structure and function. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants ...
Gui Jian-Fang (jfgui@ihb.ac.cn), Wu Nan (wunan@ihb.ac.cn), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol and Biotechnol, Wuhan 430072, Peoples R China, Wu Nan   +3 more
core  

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Histone acetyltransferase HAT1 regulates intestinal stem cell proliferation and differentiation. [PDF]

J Biol Chem
Nagarajan P, Martin CJ, Keller AR, Akkaya-Colak KB, Festing MH, Mihaylova MM, Parthun MR.   +6 more
europepmc   +1 more source

Histone Acetyltransferase and Deacetylase Inhibitors-New Aspects and Developments. [PDF]

Int J Mol Sci, 2023
Ibrahim HS, Sippl W.
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Butyrate causes loss of specific acetylation by the histone acetyltransferase p300. [PDF]

iScience
Jiang M, Psoma A, Lyu J, Chiariello MG, Modderman R, Bianchi F, Incarnato D, Marrink SJ, Jonkers IH, van den Bogaart G.   +9 more
europepmc   +1 more source