Results 21 to 30 of about 182,599 (256)

Histone acetyltransferase GCN5 contributes to cell wall integrity and salt stress tolerance by altering the expression of cellulose synthesis genes

The Plant Journal, 2018
Excess soluble salts in soil are harmful to the growth and development of most plants. Evidence is emerging that the plant cell wall is involved in sensing and responding to salt stress, but the underlying mechanisms are not well understood.
Mei Zheng, Xingbei Liu, Jingchen Lin, Xinye Liu, Zhouying Wang, Mingming Xin, Yingyin Yao, Huiru Peng, Daoxiu Zhou, Z. Ni, Qixin Sun, Zhaorong Hu   +11 more
semanticscholar   +1 more source

Histone acetyltransferase MoHat1 acetylates autophagy-related proteins MoAtg3 and MoAtg9 to orchestrate functional appressorium formation and pathogenicity in Magnaporthe oryzae

Autophagy, 2019
Macroautophagy/autophagy is critical for normal appressorium formation and pathogenicity of the rice blast fungus Magnaporthe oryzae, but the molecular base of autophagy linked to pathogenicity remains elusive in this or other pathogenic fungi.
Ziyi Yin, Chen Chen, Jie Yang, Wanzhen Feng, Xinyu Liu, Rongfang Zuo, Jingzhen Wang, Lina Yang, Kaili Zhong, Chuyun Gao, Haifeng Zhang, Xiaobo Zheng, Ping Wang, Zhengguang Zhang   +13 more
semanticscholar   +1 more source

Epigenetic reprogramming by histone acetyltransferase HAG1/AtGCN5 is required for pluripotency acquisition in Arabidopsis

EMBO Journal, 2018
Shoot regeneration can be achieved in vitro through a two‐step process involving the acquisition of pluripotency on callus‐induction media (CIM) and the formation of shoots on shoot‐induction media. Although the induction of root‐meristem genes in callus
Ji-Yun Kim, Woorim Yang, Joachim Forner, J. Lohmann, B. Noh, Yoo-Sun Noh   +5 more
semanticscholar   +1 more source

Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis

Oxidative Medicine and Cellular Longevity, 2019
Histone acetylation plays a major role in epigenetic regulation of gene expression. Monocyte-derived macrophages express functional NADPH oxidase 5 (Nox5) that contributes to oxidative stress in atherogenesis.
M. Vlad, S. Manea, A. Lazar, M. Raicu, H. Muresian, M. Simionescu, A. Manea   +6 more
semanticscholar   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Structure of the NuA4 histone acetyltransferase complex

Proceedings of the National Academy of Sciences, 2022
Nucleosome acetyltransferase of H4 (NuA4), one of two major histone acetyltransferase complexes in Saccharomyces cerevisiae  specifically acetylates histone H2A and H4, resulting in increased transcriptional activity.
Liting Ji, Lixia Zhao, Ke Xu, Huihan Gao, Yang Zhou, Roger D. Kornberg, Heqiao Zhang   +6 more
openaire   +2 more sources

Histone acetyltransferase GCN5-mediated regulation of long non-coding RNA At4 contributes to phosphate starvation response in Arabidopsis

Journal of Experimental Botany, 2019
The histone acetyltransferase GCN5 modulates the phosphate starvation response by acetylating the long non-coding RNA At4.
Tianya Wang, Jiewen Xing, Zhenshan Liu, Mei Zheng, Yingyin Yao, Zhaorong Hu, Huiru Peng, Mingming Xin, Daoxiu Zhou, Z. Ni   +9 more
semanticscholar   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin

Nature Structural &Molecular Biology, 2016
Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers.
B. N. Devaiah, Chanelle Case-Borden, A. Gégonne, C. Hsu, Qingrong Chen, D. Meerzaman, A. Dey, K. Ozato, D. Singer   +8 more
semanticscholar   +1 more source

Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genes

Genes & Development, 2018
Here, Bruzzone et al. explore the relative contributions of the transcriptional coactivators Mediator and two histone acetyltransferase (HAT) complexes, NuA4 and SAGA, to RNA polymerase II association at specific genes and gene classes by rapid nuclear ...
M. Bruzzone, Sebastian Grünberg, Slawomir Kubik, G. Zentner, D. Shore   +4 more
semanticscholar   +1 more source