Results 21 to 30 of about 73,056 (295)

Sub-telomeric core X and Y' elements in S. cerevisiae suppress extreme variations in gene silencing. [PDF]

PLoS ONE, 2011
Telomere Position Effect (TPE) is governed by strong repression signals emitted by telomeres via the Sir2/3/4 Histone Deacetylase complex. These signals are then relayed by weak proto-silencers residing in the subtelomeric core X and Y' elements ...
Patricia Power, Daniel Jeffery, Muhammad Attiq Rehman, Arjun Chatterji, Krassimir Yankulov   +4 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano, Gatla, Himavanth, Vancura, Ales, Vancurova, Ivana   +3 more
core   +2 more sources

Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning [PDF]

, 2008
Peer reviewedPublisher ...
Botsios, Sotirios, Donaldson, Anne D., Hiraga, Shin-Ichiro   +2 more
core   +3 more sources

The epigenetic regulatory effect of histone acetylation and deacetylation on skeletal muscle metabolism-a review

Frontiers in Physiology, 2023
Skeletal muscles, the largest organ responsible for energy metabolism in most mammals, play a vital role in maintaining the body’s homeostasis.
Junjie Xu, Chenglong Li, Xiaolong Kang
doaj   +1 more source

Regulating histone acetyltransferases and deacetylases [PDF]

EMBO reports, 2003
Histone acetyltransferases and histone deacetylases regulate the acetylation of histones and transcription factors, and in doing so have major roles in the control of cell fate. Many recent results have indicated that their function is strictly regulated in cells through the modulation of their levels, activity and availability for interaction with ...
Gaëlle, Legube, Didier, Trouche
openaire   +2 more sources

Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification [PDF]

, 2016
The photoreceptor UV RESISTANCE LOCUS 8 (UVR8) specifically mediates photomorphogenic responses to UV-B wavelengths. UVR8 acts by regulating transcription of a set of genes, but the underlying mechanisms are unknown. Previous research indicated that UVR8
Herzyk, Pawel, Jenkins, Gareth I., Velanis, Christos N.   +2 more
core   +1 more source

Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase [PDF]

, 2017
Human p300 is a polyhedric transcriptional coactivator, playing a crucial role by acetylating histones on specific lysine residues. A great deal of evidences shows that p300 is involved in several diseases as leukemia, tumors and viral infection.
Alberter, Arif, Artico, Azoulay, Balasubramanyam, Barreca, Brown, Chen, Choi, Costi, Costi, Dekker, Devipriya, Eckner, Farid, Gao, Getun, Ghizzoni, Granchi, Iyer, Iyer, Iyer, Kurdistani, Ligeret, Liu, Maddox, Mai, Maksimoska, Marcu, Noh, Osman, Ravindra, Robles, Sherman, Sherman, Sterner, Stimson, Thompson, Tintori, Toth, Tuccinardi, Valor, Vempati, Wang, Wong, Yasufumi, Zhao, Zheng, Zheng, Zhu   +49 more
core   +1 more source

Functional tug of war between kinases, phosphatases, and the Gcn5 acetyltransferase in chromatin and cell cycle checkpoint controls

G3: Genes, Genomes, Genetics, 2023
Covalent modifications of chromatin regulate genomic structure and accessibility in diverse biological processes such as transcriptional regulation, cell cycle progression, and DNA damage repair.
Qihao Liu, Lorraine Pillus, Emily L Petty   +2 more
doaj   +1 more source

Unmasking the biological function and regulatory mechanism of NOC2L: a novel inhibitor of histone acetyltransferase

Journal of Translational Medicine, 2023
NOC2 like nucleolar associated transcriptional repressor (NOC2L) was recently identified as a novel inhibitor of histone acetyltransferase (INHAT).
Siyi Lu, Zhaoyu Chen, Zhenzhen Liu, Zhentao Liu   +3 more
doaj   +1 more source