Results 181 to 190 of about 24,866 (282)
Characterization of a cytoplasmic histone—coenzyme A acetyltransferase [PDF]
Pestaña, Angel +2 more
openaire +2 more sources
The role of histone acetyltransferases in plant homeostasis
Food insecurity and malnutrition are driven by food system challenges. Bioscience provides a strong foundation to address these challenges. Reversible epigenetic changes, including histone acetylation, are emerging as an important regulatory junction ...
Dadarou, Despoina
core
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy +4 more
wiley +1 more source
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5. [PDF]
Hatakeyama D +14 more
europepmc +1 more source
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan +16 more
wiley +1 more source
The Fusarium graminearum Histone Acetyltransferases Are Important for Morphogenesis, DON Biosynthesis, and Pathogenicity. [PDF]
Kong X +8 more
europepmc +1 more source
A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source

