Results 251 to 260 of about 241,476 (303)

The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention‐deficit/hyperactivity disorder

The Journal of Physiology, Volume 604, Issue 14, Page 5711-5730, 15 July 2026.
Abstract figure legend Pregestational stress modifies germ‐cell epigenetic information, resulting in GABAergic dysfunction and E/I imbalance in the developing brain, thereby increasing susceptibility to ASD‐and ADHD‐related neurodevelopmental abnormalities in offspring.
Samaneh Ahmadian‐Moghadam, Ehsan Saboory, Shiva Roshan‐Milani   +2 more
wiley   +1 more source

Histone Modifications: Decoding the Epigenetic Basis of Economic Traits in Livestock and Poultry. [PDF]

Genes (Basel)
Su Y, Li W, Lv Q, Su R.
europepmc   +1 more source

Fueling silence: Metabolic control of latent viral infection. [PDF]

PLoS Pathog
You H, Guo R.
europepmc   +1 more source

Acetylation modification in malignant progression and therapeutic resistance of gliomas. [PDF]

Front Cell Dev Biol
Zhang J, Wang M, Wang H, Jiang X, Zou H.
europepmc   +1 more source

Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. [PDF]

Journal of Medicinal Chemistry, 2020
p300/CBP are ubiquitously expressed pleiotropic lysine acetyl transferases and play a key role as transcriptional co-activators that are essential for a multitude of cellular processes.
Yaxi Yang, Rukang Zhang, Zhaojun Li, Lianghe Mei, Shili Wan, H. Ding, Z. Chen, Jing Xing, Hui-jin Feng, Jie Han, Hualiang Jiang, M. Zheng, C. Luo, Bing Zhou   +13 more
semanticscholar   +14 more sources

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Histone acetyltransferases.

Annual Review of Biochemistry, 2001
▪ Abstract  Transcriptional regulation in eukaryotes occurs within a chromatin setting and is strongly influenced by nucleosomal barriers imposed by histone proteins. Among the well-known covalent modifications of histones, the reversible acetylation of internal lysine residues in histone amino-terminal domains has long been positively linked to ...
S. Roth, J. Denu, C. Allis
semanticscholar   +3 more sources

Role of histone acetyltransferases MOF and Tip60 in genome stability.

DNA Repair, 2021
U. S. Mir, Audesh Bhat, Arjamand Mushtaq, Shruti Pandita, Mohammad Altaf, T. Pandita   +5 more
semanticscholar   +3 more sources

Histone acetyltransferases: function, structure, and catalysis

Current Opinion in Genetics & Development, 2001
Histone acetyltransferases (HATs) directly link chromatin modification to gene activation. Recent structure/function studies provide insights into HAT catalysis and histone binding, and genetic studies suggest cross-talk between acetylation and other histone modifications.
R, Marmorstein, S Y, Roth
openaire   +4 more sources

5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.

Cancer Letters, 2017
Chang-zheng Du, Dandan Huang, Yi-fan Peng, Yun-feng Yao, Ying Zhao, Yang Yang, Haiying Wang, Linlin Cao, Wei-Guo Zhu, J. Gu   +9 more
semanticscholar   +3 more sources

Small Molecule Inhibitors of Histone Acetyltransferases as Epigenetic Tools and Drug Candidates

Archiv Der Pharmazie, 2012
Silviya D. Furdas, S. Kannan, W. Sippl, M. Jung   +3 more
semanticscholar   +3 more sources