Results 251 to 260 of about 24,866 (282)

The MYST Family of Histone Acetyltransferases

2003
Multiple chromatin modifying proteins and multisubunit complexes have been characterized in recent years. Histone acetyltransferase (HAT) activities have been the most thoroughly studied, both biochemically and functionally. This review sums up the current knowledge on a specific group of proteins that is extremely well conserved throughout evolution ...
R T, Utley, J, Côté
openaire   +2 more sources

Mammalian histone acetyltransferases and their complexes

Cellular and Molecular Life Sciences, 2001
One of the key questions in the current molecular genetics of eukaryotes is how genetic information is retrieved from tightly packed chromatin. Acetylation of core histone N-termini is implicated in the regulation of chromatin function, and I summarize what is known about the mammalian enzymes that promote this posttranslational histone modification ...
openaire   +2 more sources

Measurement of histone acetyltransferase and histone deacetylase activities and kinetics of histone acetylation

Methods, 2003
Dynamic histone acetylation has a role in chromatin remodeling and in the regulation of transcription. Histone deacetylases (HDACs) and histone acetyltransferases (HATs) catalyze reversible histone acetylation. HATs and HDACs exist as multiprotein complexes that have coactivator and corepressor activities, respectively.
Jian-Min, Sun, Virginia A, Spencer, Hou Yu, Chen, Lin, Li, James R, Davie   +4 more
openaire   +2 more sources

Histone acetyltransferases and histone deacetylases of Physarum polycephalum

Cell Biology International Reports, 1992
Abstract DEAE-Sepharose chromatography of plasmodial extracts of the myxomycete Physarum polycephalum reveals the presence of multiple histone acetyltransferases and histone deacetylases. Five putative histone acetyltransferases and histone deacetylases.
G BROSCH, G LOPEZRODAS, G GOLDERER, H LINDNER, P GROBNER, P LOIDL   +5 more
openaire   +1 more source

Histone Acetyltransferase Complexes and Their Link to Transcription

Critical Reviews™ in Eukaryotic Gene Expression, 1999
Early studies revealing the relationship between the state of histone acetylation and gene transcription were largely indirect. Increasing information regarding the enzymes that catalyze transcription linked acetylation is beginning to clarify this issue.
L, Howe, C E, Brown, T, Lechner, J L, Workman   +3 more
openaire   +2 more sources

The diverse functions of histone acetyltransferase complexes

Trends in Genetics, 2003
Although histone acetylation has historically been linked to transcription activation, recent studies indicate that this modification and the enzymes that catalyze it have much broader and diverse functions. Histone acetyltransferase complexes are involved in such diverse processes as transcription activation, gene silencing, DNA repair and cell-cycle ...
Michael J, Carrozza, Rhea T, Utley, Jerry L, Workman, Jacques, Côté   +3 more
openaire   +2 more sources

Histone acetyltransferases in control.

Current biology : CB, 1997
Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.
P A, Wade, A P, Wolffe
openaire   +1 more source

Histone Acetyltransferases

2015
Yepeng Luan, Liza Ngo, Zhen Han, Xuejian Wang, Meihua Qu, Y. George Zheng   +5 more
openaire   +2 more sources

Histone acetyltransferases and histone deacetylases of trichoderma

2023
Vivek Sharma, Richa Salwan
openaire   +1 more source

Role of histone acetyltransferases MOF and Tip60 in genome stability

DNA Repair, 2021
Audesh Bhat, Arjamand Mushtaq, Shruti Pandita   +2 more
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