Results 241 to 250 of about 37,852 (313)

Synthesis of 2‐Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti‐Angiogenesis Properties

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
2‐Aryl(alkyl)benzimidazole hydroxamic acids (11‐16) are potent and selective HDAC6 inhibitors, with minimal activity against HDAC1/2, and also display anti‐angiogenic and anticancer activities. Compound 13 exhibited a GI50 of 3.9 μM against EPCs and inhibited the growth of HCT‐116, SK‐Hep‐1, and PC‐3 cells with GI50 values of 1.3, 4.2, and 7.5 μM ...
Yi‐Ting Liu, Cheng‐Ta Lai, Shih‐Wei Wang, Shan‐Chi Liu, Yi‐Lin Hwang, Yi‐Chen Tsai, Chi‐Yeh Lee, Yu‐Wei Lai, Juei‐Yu Yen, Po‐Chuan Wang, Hsueh‐Yun Lee   +10 more
wiley   +1 more source

Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases. [PDF]

ACS Med Chem Lett, 2018
Michaelides MR, Kluge A, Patane M, Van Drie JH, Wang C, Hansen TM, Risi RM, Mantei R, Hertel C, Karukurichi K, Nesterov A, McElligott D, de Vries P, Langston JW, Cole PA, Marmorstein R, Liu H, Lasko L, Bromberg KD, Lai A, Kesicki EA.   +20 more
europepmc   +1 more source

Organ specificity of histone Acetyltransferases

FEBS Letters, 1971
openaire   +2 more sources

Comparison of the expression profiles of two human histone acetyltransferase gene homologs in Drosophila melanogaster

, 2006
Vijayalakshmi Ramakrishnan, Felice Elefant   +1 more
openalex   +1 more source

NF-Y Is Associated with the Histone Acetyltransferases GCN5 and P/CAF [PDF]

, 1998
A Currie
openalex   +1 more source

Elongator subunit 3 positively regulates plant immunity through its histone acetyltransferase and radical S-adenosylmethionine domains

, 2013
Christopher DeFraia, Yongsheng Wang, Jiqiang Yao, Zhonglin Mou   +3 more
openalex   +1 more source

Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers [PDF]

, 2013
Masayoshi Iizuka, Takao Susa, Yoshihisa Takahashi, Mimi Tamamori‐Adachi, Takashi Kajitani, Hiroko Okinaga, Toshio Fukusato, Tomoki Okazaki   +7 more
openalex   +1 more source

MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98 -Rearranged Acute Myeloid Leukemia [PDF]

Nicole L. Michmerhuizen, Emily Heikamp, Ilaria Iacobucci, Masayuki Umeda, Bright Arthur, Vibhor Mishra, Danika Di Giacomo, Ryan Hiltenbrand, Qingsong Gao, Sandi Radko-Juettner, Josi Lott, Cynthia Martucci, Varsha Subramanyam, Charlie Hatton, Pradyuamna Baviskar, Pablo Portola, Aurelie Claquin, Bappaditya Chandra, David W. Baggett, Ali Khalighifar, Hongling Huang, Peipei Zhou, Lingyun Long, Hao Shi, Yu Sun, Evangelia K. Papachristou, Chandra Chilamakuri, Francisca N. de Luna Vitorino, Joanna M. Gongora, Laura J. Janke, Alex Kentsis, Clive S. D’Santos, Benjamin A. Garcia, Richard W. Kriwacki, Hongbo Chi, Jeffery M. Klco, Scott A. Armstrong, Charles G. Mullighan   +37 more
openalex   +1 more source

Dysregulation of histone acetyltransferases and deacetylases in cardiovascular diseases. [PDF]

Oxid Med Cell Longev, 2014
Wang Y, Miao X, Liu Y, Li F, Liu Q, Sun J, Cai L.   +6 more
europepmc   +1 more source

Identification of the histone acetyltransferase gene family in the Platycodon grandiflorus genome [PDF]

Yang Xiang, Jingzhi Wan, Yong Ling Liao
openalex   +1 more source