Results 241 to 250 of about 241,476 (303)

Dissecting the Molecular Roles of Histone Chaperones in Histone Acetylation by Type B Histone Acetyltransferases (HAT-B). [PDF]

J Biol Chem, 2015
Haigney A, Ricketts MD, Marmorstein R.
europepmc   +1 more source

Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof‐of‐Concept Synthesis of Landscape‐Level Regulation

Journal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh, Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter   +3 more
wiley   +1 more source

Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma. [PDF]

Leuk Lymphoma, 2016
Haery L, Mussakhan S, Waxman DJ, Gilmore TD.   +3 more
europepmc   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

CfSnt2‐CfRpd3‐Mediated H3 Deacetylation Governs the ROS‐Induced Autophagy and Pathogenicity of Colletotrichum fructicola

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
The CfSnt2‐CfRpd3‐mediated H3 deacetylation negatively regulates ROS‐induced autophagy. The CfRpd3 and CfSnt2 undergo down‐regulated expression to relieve the inhibition of autophagy. Thus, autophagy is highly induced during Colletotrichum fructicola infection and oxidative stress for ROS response and pathogenicity.
Yuan Guo, He Li, Shengpei Zhang
wiley   +1 more source

Postbiotic Stool Filtrates From Patients With Type 2 Diabetes Impair Mouse Intestinal Muscle Contractility Ex Vivo and Alter Enteric Cholinergic Neuronal Activity in Vivo

Neurogastroenterology &Motility, Volume 38, Issue 7, July 2026.
We previously showed that molecules solubilized in filter‐sterilized stool filtrates (postbiotic stool filtrates; PSFs) of mice fed a high‐fat diet (HFD) may have a role in triggering damage to the enteric nervous system and gut dysmotility before the onset of T2D symptoms. To translate these results, we studied the effects of PSFs from male and female
Peter F. Voller, Cameron S. Bowen, Afiya Aunjum, Gillian Glivar, Ashlyn Riddle, Barrett Abendroth, Theodore Schultz, Lauren Fitzgerald, Emily Vergara, Logan Durk, Maximilian T. Antush, Drew Ault, Rayme Geidl, Chantal A. Vella, Onesmo B. Balemba   +14 more
wiley   +1 more source

Sex- and skeletal muscle-specific gene expression response of histone 3 lysine 27-modifying enzymes by voluntary running in mice. [PDF]

Physiol Rep
Gamu D, Cameron M, Jalil Y, Zouaoui I, Sangha J, Kim J.   +5 more
europepmc   +1 more source

An N‐acetyltransferase‐MAPK fusion protein modulates developmental reprogramming in Physcomitrium patens

New Phytologist, Volume 251, Issue 1, Page 321-339, July 2026.
Summary We discovered a previously uncharacterized moss‐specific protein, Rosetta NATD‐MAPK 1 (RAK1) in Physcomitrium patens, which uniquely integrates MAP kinase (MAPK)‐dependent signaling with N‐acetyltransferase activity. Through phenotypical and biochemical analyses, we characterized RAK1 function in the regulation of the 2D‐to‐3D growth transition.
Cloe de Luxán‐Hernández, Thomas J. Ammitsøe, Jakob V. Kanne, Sabrina Stanimirovic, Rocío Redondo‐Rodríguez, Milena E. Roux, Liechi Zhang, Zoe Weeks, Michael Schutzbier, Gerhard Dürnberger, Elisabeth Roitinger, Oliver Spadiut, Masaki Ishikawa, Mitsuyasu Hasebe, Laura A. Moody, Yasin F. Dagdas, Eleazar Rodriguez, Morten Petersen   +17 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, Volume 102, Issue 4, Page 780-796, July/August 2026.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Hierarchical small molecule inhibition of MYST acetyltransferases. [PDF]

Nat Commun
Chen X, Castroverde A, Perez M, Holewinski R, Suazo KF, Karki R, Andresson T, Garcia BA, Meier JL.   +8 more
europepmc   +1 more source