Results 1 to 10 of about 60,846 (261)

Primed histone demethylation regulates shoot regenerative competency [PDF]

Nature Communications, 2019
Plant regeneration can occur via formation of a mass of pluripotent cells known as callus. Here, Ishihara et al. show that acquisition of regenerative capacity of callus-forming cells requires a lysine-specific demethylase that removes H3K4me2 to prime ...
Hiroya Ishihara, Kaoru Sugimoto, Paul T. Tarr, Haruka Temman, Satoshi Kadokura, Yayoi Inui, Takuya Sakamoto, Taku Sasaki, Mitsuhiro Aida, Takamasa Suzuki, Soichi Inagaki, Kengo Morohashi, Motoaki Seki, Tetsuji Kakutani, Elliot M. Meyerowitz, Sachihiro Matsunaga   +15 more
doaj   +7 more sources

Asparagine starvation suppresses histone demethylation through iron depletion [PDF]

iScience, 2023
Summary: Intracellular α-ketoglutarate is an indispensable substrate for the Jumonji family of histone demethylases (JHDMs) mediating most of the histone demethylation reactions.
Jie Jiang, Sankalp Srivastava, Sheng Liu, Gretchen Seim, Rodney Claude, Minghua Zhong, Sha Cao, Utpal Davé, Reuben Kapur, Amber L. Mosley, Chi Zhang, Jun Wan, Jing Fan, Ji Zhang   +13 more
doaj   +5 more sources

Effect of ribose-glycated BSA on histone demethylation [PDF]

Frontiers in Genetics, 2022
A reducing sugar reacts with the protein, resulting in advanced glycation end-products (AGEs), which have been implicated in diabetes-related complications.
Mengqi Xi, Lingyun Zhang, Yan Wei, Ting Li, Meihua Qu, Qian Hua, Rongqiao He, Ying Liu   +7 more
doaj   +4 more sources

RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation. [PDF]

PLoS ONE, 2009
Gammaherpesviruses have a common biological characteristic, latency and lytic replication. The balance between these two phases in murine gammaherpesvirus 68 (MHV-68) is controlled by the replication and transcription activator (RTA) gene. In this report,
Zhangsheng Yang, Haidong Tang, Hai Huang, Hongyu Deng   +3 more
doaj   +3 more sources

Transcriptional regulation of 15-lipoxygenase expression by histone h3 lysine 4 methylation/demethylation. [PDF]

PLoS ONE, 2012
15-Lipoxygenase-1 (15-LOX-1) oxidizes polyunsaturated fatty acids to a rich spectrum of biologically active metabolites and is implicated in physiological membrane remodelling, inflammation and apoptosis.
Cheng Liu, Dawei Xu, Hongya Han, Yidong Fan, Frida Schain, Zhonghua Xu, Hans-Erik Claesson, Magnus Björkholm, Jan Sjöberg   +8 more
doaj   +3 more sources

Oncogenic role of ALX3 in cervical cancer cells through KDM2B-mediated histone demethylation of CDC25A. [PDF]

BMC Cancer, 2021
Qi J, Zhou L, Li D, Yang J, Wang H, Cao H, Huang Y, Zhang Z, Chang L, Zhu C, Zhan J, Yuan Y.   +11 more
europepmc   +3 more sources

Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation. [PDF]

J Biol Chem, 2022
Martinez CA, Jiramongkol Y, Bal N, Alwis I, Nedoboy PE, Farnham MMJ, White MD, Cistulli PA, Cook KM.   +8 more
europepmc   +3 more sources

Dissecting contributions of catalytic and reader domains in regulation of histone demethylation. [PDF]

Methods Enzymol, 2020
Petronikolou N, Longbotham JE, Fujimori DG.   +2 more
europepmc   +3 more sources

Arabidopsis TRB Proteins Form Two Closely Related Complexes to Mediate H3K4me3 Demethylation and Transcriptional Repression [PDF]

Advanced Science
The Arabidopsis telomere repeat binding proteins TRB1, TRB2, and TRB3 (TRB1/2/3) are components of the PWWP‐EPCR‐ARID‐TRB (PEAT) complex, which is involved in histone acetylation and H2A deubiquitination.
Qi Wang, Dan‐Yang Yuan, Yu‐Jia Lu, Xin Wang, Hao Zheng, Lin Li, She Chen, Xin‐Jian He   +7 more
doaj   +2 more sources

Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation. [PDF]

J Immunol, 2020
Yang X, Bam M, Becker W, Nagarkatti PS, Nagarkatti M.   +4 more
europepmc   +3 more sources