Results 231 to 240 of about 1,862,085 (289)

Coordinated action of multiple active histone modifications shapes the zygotic genome activation in teleost embryos. [PDF]

Nat Commun
Fukushima HS, Takeda H.
europepmc   +1 more source

An assessment of histone-modification antibody quality

, 2010
Thea A. Egelhofer, Aki Minoda, Sarit Klugman, Kyungjoon Lee, Paulina Kolasinska-Zwierz, Artyom A. Alekseyenko, Ming-Sin Cheung, Daniel S. Day, Sarah Gadel, Andrey A. Gorchakov, Tingting Gu, Peter V. Kharchenko, Samantha Kuan, Isabel Latorre, Daniela Linder-Basso, Ying Luu, Queminh Ngo, Marc D. Perry, Andreas Rechtsteiner, Nicole C. Riddle, Yuri B. Schwartz, Gregory Shanower, Anne Vielle, Julie Ahringer, Sarah C. R. Elgin, Mitzi I. Kuroda, Vincenzo Pirrotta, Bing Ren, Susan Strome, Peter J. Park, Gary H. Karpen, R. David Hawkins, Jason D. Lieb   +32 more
openalex   +2 more sources

Generalized nucleation and looping model for epigenetic memory of histone modifications

Proceedings of the National Academy of Sciences of the United States of America, 2016
Fabian Erdel, E. Greene
semanticscholar   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Histone modifications and metabolic reprogramming in tumor-associated macrophages: a potential target of tumor immunotherapy. [PDF]

Front Immunol
Xu Y, Zhang H, Nie D.
europepmc   +1 more source

Fluoroalkene modification of mercaptoacetamide-based histone deacetylase inhibitors

, 2009
Satoshi Osada, Satoshi Sano, Mariko Ueyama, Yoshiro Chuman, Hiroaki Kodama, Kazuyasu Sakaguchi   +5 more
openalex   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
wiley   +1 more source

Lactoferrin supplementation modulates the oxidative and metabolic genes by NR5A2-mediated histone modifications in deoxynivalenol-induced ileum injury. [PDF]

Stress Biol
Guo X, Yuan X, Xu Z, Liu J, Lv R, Gao Y, Xu W, Ji D, Guo Y.   +8 more
europepmc   +1 more source

Genistein Affects Histone Modifications on Dickkopf-Related Protein 1 (DKK1) Gene in SW480 Human Colon Cancer Cell Line

, 2012
Huan Wang, Qian Li, Hong Chen
openalex   +2 more sources