Results 41 to 50 of about 723,033 (304)
Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction
eLife, 2020 The H2A.Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription start sites in all eukaryotes. H2A.Z is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms.
Anand Ranjan +15 more
doaj +1 more source
Biology Open, 2014 In animals, replication-independent incorporation of nucleosomes containing the histone variant H3.3 enables global reprogramming of histone modifications and transcriptional profiles.
Xin Nie +4 more
doaj +1 more source
The histone H2A variant macroH2A1 does not localize to the centrosome. [PDF]
PLoS ONE, 2011 MacroH2A1 is a histone H2A variant which contains a large non-histone C-terminal region of largely unknown function. Within this region is a macro domain which can bind ADP-ribose and related molecules.
Nathalie Friedman +3 more
doaj +1 more source
Sequence-dependent histone variant positioning signatures [PDF]
, 2010 Background: Nucleosome, the fundamental unit of chromatin, is formed by wrapping nearly 147bp of DNA around an octamer of histone proteins. This histone core has many variants that are different from each other by their biochemical compositions as well ...
Bich Ho +5 more
core +1 more source
Histone variants in skeletal myogenesis
Epigenetics, 2020 Histone variants regulate chromatin accessibility and gene transcription. Given their distinct properties and functions, histone varint substitutions allow for profound alteration of nucleosomal architecture and local chromatin landscape. Skeletal myogenesis driven by the key transcription factor MyoD is characterized by precise temporal regulation of ...
NANDINI KARTHIK, RESHMA TANEJA
openaire +4 more sources
Histone H2A Has a Novel Variant in Fish Oocytes
, 2009 Histone variants and their modification have significant roles in many cellular processes. In this study, we identified and characterized the histone H2A variant h2af1o in fish and revealed its oocyte-specific expression pattern during oogenesis and ...
Yue, Hua-Mei +4 more
core +1 more source
The histone H3 lysine 36 methyltransferase HypB facilitates embryonic stem cell differentiation [PDF]
, 2007 Histone H3 lysine 36 (H3K36) methylation was identified as a conserved modification from yeast to human. In yeast, biochemical characterization of the SET2 protein and genome wide mapping of H3K36me2 and K36me3 indicate that H3K36 methylation functions ...
Wang, Tianke
core +1 more source
Histone H1 binding is inhibited by histone variant H3.3 [PDF]
The EMBO Journal, 2009 Linker histones are involved in the formation of higher-order chromatin structure and the regulation of specific genes, yet it remains unclear what their principal binding determinants are. We generated a genome-wide high-resolution binding map for linker histone H1 in Drosophila cells, using DamID. H1 binds at similar levels across much of the genome,
Ulrich, Braunschweig +3 more
openaire +2 more sources
H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization. [PDF]
, 2013 Histone lysine (K) methylation has been shown to play a fundamental role in modulating chromatin architecture and regulation of gene expression. Here we report on the identification of histone H3K56, located at the pivotal, nucleosome DNA entry/exit ...
Pünzeler, Sebastian +39 more
core +2 more sources
Dynamic chromatin: concerted nucleosome remodelling and acetylation [PDF]
, 2005 The flexibility of chromatin that enables translation of environmental cues into changes in genome utilisation, relies on a battery of enzymes able to modulate chromatin structure in a highly targeted and regulated manner.
Eberharter, Anton +2 more
core +1 more source