Results 111 to 120 of about 129,047 (304)
, 2017 Isaac Ginsburg,1 Peter Vernon van Heerden,2 Erez Koren1 1Institute of Dental Sciences, Faculty of Dental Medicine, The Hebrew University of Jerusalem, 2General Intensive Care Unit, Hadassah University Hospital, Jerusalem, Israel Abstract: This paper ...
Ginsburg I, van Heerden PV, Koren E
core
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Biomolecular Recognition of Methylated Histones
, 2019 Lysine and arginine methylations are among the most abundant posttranslational modifications found on histone proteins. The recognition of methylated lysine and arginine residues by epigenetic reader proteins provides an important molecular requirement ...
Porzberg, Miriam +5 more
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Advanced Healthcare Materials, EarlyView.Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi +8 more
wiley +1 more source
Progress in the treatment of pediatric H3 K27M mutant diffuse midline glioma
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 The high-grade glioma, H3 K27M mutant diffuse midline glioma tends to occur in children, and its high malignancy lead to very poor prognosis after treatment (median survival after diagnosis < 1 year).
Min⁃jie LUO +2 more
doaj
Le code épigénétique des histones
, 2003 Il est devenu évident que les modifications post-traductionnelles des histones sont des acteurs majeurs dans les mécanismes de régulation transcriptionnelle.
Lacoste, Nicolas +3 more
core +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
Advanced Science, EarlyView.ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Prediction of the conformation of the histones
, 1976 The secondary structures of the histones, H1, H2A, H2B, H3, and H4 have been predicted utilizing the predictive scheme of Chou and Fasman (Biochemistry 13:211, 222[1974]) and a new set of conformational parameters based on the X-ray data of 29 protein ...
Fasman, G.D., Adler, A.J., Chou, P.Y.
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Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Histones induced TF expression in endothelial cells.
, 2016 (A) After EA.hy926 cells were stimulated with various levels of calf thymus histones for 4 h, the surface expression of TF antigens was determined by flow cytometry.
Hyun Kyung Kim (287966) +3 more
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