Results 141 to 150 of about 66,203 (260)

Medical Knowledge Integration Into Reinforcement Learning Algorithms for Dynamic Treatment Regimes

International Statistical Review, EarlyView.
Summary The goal of precision medicine is to provide individualised treatment at each stage of chronic diseases, a concept formalised by dynamic treatment regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from clinical data to enhance therapeutic effectiveness.
Sophia Yazzourh, Nicolas Savy, Philippe Saint‐Pierre, Michael R. Kosorok   +3 more
wiley   +1 more source

Structural Vulnerability in Health Research: A Systematic Mixed Studies Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To systematically examine how structural vulnerability has been defined and operationalised in United States‐based health research, identify conceptual consistencies and methodological gaps, and propose core dimensions of structural vulnerability along with implications for future application in health research.
Levia A. Sutton, Carmen Alvarez, Therese S. Richmond, Sara F. Jacoby   +3 more
wiley   +1 more source

Use of Conventional Artificial Intelligence Methods in the Identification of Frailty: A Scoping Review

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Early identification and management of frailty are crucial, yet its detection in early stages remains difficult for clinicians. Artificial intelligence (AI) has emerged as a promising tool in healthcare. However, the absence of a standard frailty definition and diversity of AI methods create a need for a comprehensive review.
Kunal Ashok Dalsania, Alixe Ménard, Shruthi Sundararaman, Arya Rahgozar, Sarah de Lima, Xintong Lu, Aya Al‐Ali, Krishnpriya Singh, Ramtin Hakimjavadi, Hui Yan, Claire Sethuram, Howard Bergman, Jim LaPlante, Daniel McIsaac, Samira Abbasgholizadeh Rahimi, Nadia Sourial, Manpreet Thandi, Sabrina Wong, Clare Liddy, Karen Bandeen‐Roche, Sathya Karunananthan   +20 more
wiley   +1 more source

Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson, Eva Sudbury, Rija Khanal, Jade Woon, Jennifer Schaefer, Georgia Paxton   +5 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

The Dichotomy of Curaxin Compounds in HIV-1 Latency

, 2022
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Microbiology and Immunology, 2018.Combination antiretroviral therapy (cART), a regimen comprised of three or more antiretroviral drugs, has been the standard of care for ...
Jean, Maxime Junior, Zhu, Jian
core  

The Cross and Conflict: How Do Christians Impact Protest Dynamics?

Journal for the Scientific Study of Religion, EarlyView.
ABSTRACT This study examines the relationship between Christian actors, practices, and sacred sites in US protests and demonstrations, focusing on how political ideology shapes conflict outcomes. Using event‐level data from the Armed Conflict Location & Event Data Project (ACLED), the analysis explores 63,000 protest events from 2020 to 2024 ...
Joel Day
wiley   +1 more source

HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells.

PLoS Pathogens
Antiretroviral therapy (ART) has dramatically improved the clinical prognosis for people with HIV and prevents HIV transmission. However, ART does not cure HIV infection because of a persistent, latent viral reservoir in long-lived cells such as central ...
Catherine A Lewis, David M Margolis, Edward P Browne   +2 more
doaj   +1 more source

Bret/BRAT

Critical Quarterly, EarlyView.
Nicholas Smart
wiley   +1 more source

Regulating critical technologies: National security and intellectual property

The Journal of World Intellectual Property, EarlyView.
Abstract In recent years, claims of ‘national security’ have surged internationally to protect various security interests including public health, economic security and cybersecurity. National industrial strategies for building critical technologies challenge the scope of ‘national security’ in international intellectual property (IP) protection ...
Phoebe Li, Atilla Kasap
wiley   +1 more source