Results 141 to 150 of about 30,551,261 (265)

Schematic of the HIV-1 latency circuit.

, 2018
The events associated with HIV-1 transcription and translation that govern the latency of an HIV-1 infected cell are depicted as a set of reactions (see Eqs (1)–(18) in Methods).
Narendra M. Dixit (135562), Vipul Gupta (1848085)   +1 more
core   +1 more source

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

Internal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley, Philip George, Gemma Reynolds, Adam Stewart, Hang Quach, Nicole O'Leary, Zoe McQuilten, Andrea S. Henden, Lynette Chee, Chan Y. Cheah, Olivia Bupha‐Intr, Emily Blyth, Ben Teh, Monica Slavin, Michael Dickinson, Robert Weinkove   +15 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells.

PLoS Pathogens
Antiretroviral therapy (ART) has dramatically improved the clinical prognosis for people with HIV and prevents HIV transmission. However, ART does not cure HIV infection because of a persistent, latent viral reservoir in long-lived cells such as central ...
Catherine A Lewis, David M Margolis, Edward P Browne   +2 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

Galectin-1 promotes HIV-1 latency reactivation

Journal of Virus Eradication, 2019
J. Rubione, G. Duette, P. Perez, P. Pereyra Gerber, J. Salido, A. Cagnoni, L. Guzman, A. Adamczyk, O. Sued, Y. Ghiglione, N. Laufer, K. Mariño, G. Rabinovich, M. Ostrowski   +13 more
doaj   +1 more source

The role of VIF in overcoming the APOBEC3G block to HIV-1 replication [PDF]

This project focuses on the Virus Infectivity Factor protein of HIV-1 and its relief of the block to virus replication exerted by the APOBEC3G component of the innate immune response.
Kulkarni, Anurag
core  

The Cross and Conflict: How Do Christians Impact Protest Dynamics?

Journal for the Scientific Study of Religion, EarlyView.
ABSTRACT This study examines the relationship between Christian actors, practices, and sacred sites in US protests and demonstrations, focusing on how political ideology shapes conflict outcomes. Using event‐level data from the Armed Conflict Location & Event Data Project (ACLED), the analysis explores 63,000 protest events from 2020 to 2024 ...
Joel Day
wiley   +1 more source

Regulating critical technologies: National security and intellectual property

The Journal of World Intellectual Property, EarlyView.
Abstract In recent years, claims of ‘national security’ have surged internationally to protect various security interests including public health, economic security and cybersecurity. National industrial strategies for building critical technologies challenge the scope of ‘national security’ in international intellectual property (IP) protection ...
Phoebe Li, Atilla Kasap
wiley   +1 more source