Results 151 to 160 of about 66,203 (260)

Galectin-1 promotes HIV-1 latency reactivation

Journal of Virus Eradication, 2019
J. Rubione, G. Duette, P. Perez, P. Pereyra Gerber, J. Salido, A. Cagnoni, L. Guzman, A. Adamczyk, O. Sued, Y. Ghiglione, N. Laufer, K. Mariño, G. Rabinovich, M. Ostrowski   +13 more
doaj   +1 more source

Regulation of HIV-1 latency by basal transcription

, 2013
HIV/AIDS is undoubtedly one of mankind’s most pressing health concerns. Currently, there are ~34 million people infected worldwide, with ~3 million new infections and ~2 million deaths every year.
Dahabieh, Matthew Solomon
core  

Latent Profile Analysis of Generic Conspiracy Beliefs‐ Differences in Science Acceptance, Analytical and Intuitive Thinking

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT The aims of the present study were to (i) identify profiles of belief in conspiracy theories, and to (ii) test whether the obtained profiles differed in analytical (rational ability, rational engagement, Cognitive Reflection Test) and intuitive thinking (experiential ability, experiential engagement), and science denial (vaccine, climate ...
Peter Karlsson, Torbjörn Josefsson, Sara Svensson, Linus Andersson   +3 more
wiley   +1 more source

Epidemiology and Outcomes of Cryptococcal Infections in Liver Transplant Recipients: A Retrospective Cohort Study at a US Academic Center

Transplant Infectious Disease, EarlyView.
Among 346 liver transplant recipients, rural residence conferred a 3.3‐fold higher risk of cryptococcal infection — a novel finding suggesting environmental exposure or healthcare access barriers may drive susceptibility. Triple immunosuppression and longer waitlist duration were additional risk factors, with very early infection carrying the worst ...
Rachel Sigler, Chloe Hanigan, Atikur Rahman, Isuru Ratnayake, Phani Akella, Lauren Carlini, Chelsea Gorsline, Erica Mackenzie, Albert Eid, Dennis Shoemaker, Ryan Taylor, Stephen Waller   +11 more
wiley   +1 more source

International Survey on Screening and Management of Strongyloidiasis in Solid Organ Transplant Patients

Transplant Infectious Disease, EarlyView.
This international cross‐sectional survey of healthcare workers caring for solid organ transplant patients identified knowledge gaps regarding Strongyloides transmission and mortality, particularly among non‐infectious disease providers. Screening strategies varied geographically, with universal screening more common in endemic areas and targeted ...
Jacques Simkins, Akshatha Ravindra, Cameron R. Wolfe, Alessandra Mularoni, Monica Slavin, Ines Ushiro‐Lumb, John W. Baddley, Jonathan Hand, Stephanie Pouch, Maricar Malinis, Maristela P. Freire, Marcelo Radisic, Matthew B. Roberts, Ban Hock Tan, Siriorn Watcharananan, Wanessa T. Clemente   +15 more
wiley   +1 more source

Co‐Occurring Risk Factors for Tuberculosis Preventive Treatment Non‐Adherence Among People Living With HIV in Ethiopia: A Latent Class Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective Non‐adherence to tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) is a critical issue in Ethiopia and other Sub‐Saharan African countries, where both TB and HIV burdens are high. To reduce TPT non‐adherence among PLHIV, it is crucial to identify those at risk and implement targeted interventions. Therefore,
Edao Sinba Etu, Jet Fransen, Biftu Geda, Kemal Ahmed Kuti, Anteneh Fikrie, Mark Spigt   +5 more
wiley   +1 more source

Cell models of HIV-1 latency [PDF]

SCIENTIA SINICA Vitae, 2020
Wen PENG, Kai DENG
openaire   +1 more source

Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats

Transfusion, EarlyView.
Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North, Laurence Corash, Richard J. Benjamin, Nina Mufti   +3 more
wiley   +1 more source

Inhibition of ALKBH5 demethylase of m6A pathway potentiates HIV-1 reactivation from latency

Background: Current latency-reversing agents (LRAs) employed in the “shock-and-kill” strategy primarily focus on relieving epigenetic and transcriptional blocks to reactivate the latent HIV-1.
Van Lint, Carine, Maryam Bendoumou, Selberg, Simona, Alexander O. Pasternak, De Wit, Stéphane, Heng-Chang Chen, Coca Necsoi, Stéphane De Wit, Chen, Heng Chang, Pasternak, Alexander O., Chen, Heng-Chang, Antoine Dutilleul, -, Haider Ali, Karelson, Mati, Wadas, Jakub, Dutilleul, Antoine, Mati Karelson, Anna Kula-Pacurar, Bendoumou, Maryam, Carine Van Lint, Avettand-Fenoël, Veronique, Kankuri, Esko, Jakub Wadas, Lalik, Kamil, Veronique Avettand-Fenoël, Ali, Haider, Marcello, Alessandro, Simona Selberg, Nestola, Lorena, Paolo Maiuri, Haider Ali, Esko Kankuri, Pyrc, Krzysztof, Alessandro Marcello, Kula-Pacurar, Anna, Necsoi, Coca, Kamil Lalik, Maiuri, Paolo, Krzysztof Pyrc, Lorena Nestola   +39 more
core   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source