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Unravelling HIV-1 Latency, One Cell at a Time

Trends in Microbiology, 2017
A single virus is capable of infecting and replicating in a single cell. Recent advances across single-cell omics technologies - genomics, epigenomics, transcriptomics, epitranscriptomics, proteomics, and metabolomics - will offer unprecedented opportunities to gain more insights into the various aspects of the life cycle of viruses and their impact on
Kok, Yik Lim   +2 more
openaire   +3 more sources

Keeping quiet: microRNAs in HIV-1 latency

Nature Medicine, 2007
MicroRNAs contribute to HIV-1 latency in resting T cells. This finding could potentially be used in the development of therapies targeted to purge the latent reservoir in an effort to clear the body of virus (pages 1241–1247).
Yefei Han, Robert F Siliciano
openaire   +1 more source

DISCOVERING REGULATED NETWORKS DURING HIV-1 LATENCY AND REACTIVATION

Biocomputing 2006, 2005
Human immunodeficiency virus (HIV) affects millions of people across the globe. Despite the introduction of powerful anti-viral therapies, one factor confounding viral elimination is the ability of HIV to remain latent within the host genome. Here, we perform a network analysis of the viral reactivation process using human gene expression profiles and ...
Sourav, Bandyopadhyay   +2 more
openaire   +2 more sources

Role of Mirna in HIV-1 Latency

Future HIV Therapy, 2008
Postintegration latency of HIV-1 is achieved when host cells contain integrated provirus but viral particles are not being produced. When the cells are activated, infectious viruses can be produced from the cells. Latent infection is one of the important characteristics for all HIV-1 strains to survive in vivo.
openaire   +1 more source

Modeling latency reversal en HIV-1 infection

2016
info:eu-repo/semantics ...
Ribeiro, Ruy M.   +3 more
openaire   +1 more source

Novel approaches to target the microenvironment of bone metastasis

Nature Reviews Clinical Oncology, 2021
Lorenz C Hofbauer   +2 more
exaly  

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

Nature Reviews Microbiology, 2009
Mayte T Coiras   +2 more
exaly  

Multi-Connectivity as an Enabler for Reliable Low Latency Communications—An Overview

IEEE Communications Surveys and Tutorials, 2020
Marie-Theres Suer   +2 more
exaly  

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