The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy. [PDF]
Prins HAB +30 more
europepmc +1 more source
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders +21 more
wiley +1 more source
Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]
Noorsaeed S +3 more
europepmc +1 more source
Machine Learning of Personal Repertoires From Public T Cell Receptors
ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley +1 more source
The p400 complex promotes HIV-1 latency by suppressing viral transcription and altering the host cell state. [PDF]
Mori LP +9 more
europepmc +1 more source
Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors. [PDF]
Furtado Milão J +6 more
europepmc +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Traditional Medicine Extracts of <i>Gnidia sericocephala</i> and Product Nkabinde in HIV-1 Latency Reversal: Insights from J-Lat Subtype B and J-Lat Subtype C Models. [PDF]
Mngomezulu K +5 more
europepmc +1 more source
PRMT3 reverses HIV-1 latency by increasing chromatin accessibility to form a TEAD4-P-TEFb-containing transcriptional hub. [PDF]
Wang X +22 more
europepmc +1 more source

