Results 191 to 200 of about 66,203 (260)

Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]

PLoS Pathog
Noorsaeed S, AlBurtamani N, Rokan A, Fassati A.   +3 more
europepmc   +1 more source

Artificial intelligence for personalized multiple micronutrient supplementation in maternal health

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1163-1173, June 2026.
Abstract Maternal undernutrition and micronutrient deficiencies remain pervasive, contributing to adverse pregnancy outcomes and long‐term health risks for mothers and offspring. Multiple micronutrient supplementation (MMS) during pregnancy has demonstrated benefits, including reduced risks of low birth weight, small‐for‐gestational‐age births, and ...
Gabriel Davis Jones, Aris T. Papageorghiou, Hassan Shehata, Hema Divakar, Eline M. Van der Beek, Vyta Senikas, Justin C. Konje, Anne‐Beatrice Kihara, Moshe Hod, on behalf of the FIGO Committee on Women's Health and Technology   +9 more
wiley   +1 more source

The p400 complex promotes HIV-1 latency by suppressing viral transcription and altering the host cell state. [PDF]

Nucleic Acids Res
Mori LP, Li C, Venables T, McAuley AT, Getzler AJ, Wang Q, Tsuda SM, Jablonski JA, Pipkin ME, Valente ST.   +9 more
europepmc   +1 more source

Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors. [PDF]

Front Immunol, 2022
Furtado Milão J, Love L, Gourgi G, Derhaschnig L, Svensson JP, Sönnerborg A, van Domselaar R.   +6 more
europepmc   +1 more source

PACS2 Alleviates Sepsis‐Induced Myopathy by Activating ERK–MAPK Signalling Pathway to Suppress ER‐Phagy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Sepsis‐induced myopathy (SIM) is a common and life‐threatening complication, but its underlying mechanisms remain poorly understood. PACS2, a key resident protein at mitochondria‐associated endoplasmic reticulum membranes (MAMs), regulates ER homeostasis under various pathological conditions.
Xuexin Li, Zu‐an Shi, Fei He, Guo Mu, Feixiang Wang, Bowen Sun, Xiaobin Wang, Li Liu   +7 more
wiley   +1 more source

Traditional Medicine Extracts of <i>Gnidia sericocephala</i> and Product Nkabinde in HIV-1 Latency Reversal: Insights from J-Lat Subtype B and J-Lat Subtype C Models. [PDF]

Int J Mol Sci
Mngomezulu K, Khathi SP, Nkabinde SA, Nkabinde M, Ngcobo M, Gqaleni N.   +5 more
europepmc   +1 more source

CBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2. [PDF]

EMBO Rep, 2022
Wu L, Pan T, Zhou M, Chen T, Wu S, Lv X, Liu J, Yu F, Guan Y, Liu B, Zhang W, Deng X, Chen Q, Liang A, Lin Y, Wang L, Tang X, Cai W, Li L, He X, Zhang H, Ma X.   +21 more
europepmc   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Trajectories of Treatment Disruption for Chronic Outpatient Medications for U.S. Veterans During Drug Shortages

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Introduction Although drug shortages for outpatient chronic conditions commonly occur, population‐level data on how they impact patients' ability to refill prescriptions is scarce. We sought to identify distinct patterns of refill adherence following drug shortages and patient‐ and prescription‐level factors associated with adherence ...
Katie J. Suda, Xinhua Zhao, Sherrie L. Aspinall, Yaming Li, Katherine Callaway Kim, Francesca E. Cunningham, Taylor L. Boyer, Tate W. Miner, Clara Kima, Walid F. Gellad, Peter A. Glassman, Chester B. Good, Felicia Skelton, Mina Tadrous, Carolyn T. Thorpe   +14 more
wiley   +1 more source

Public Health Implications of High Cytomegalovirus Seroprevalence in Pregnancy: A Cross‐Sectional Study in Western Uganda

Public Health Challenges, Volume 5, Issue 2, June 2026.
Among immediate postpartum women in western Uganda, maternal CMV seroprevalence was high (81.2%) and was predominantly chronic or non‐primary infection. Older age, rural residence, lower education, and prior spontaneous abortion were associated with seropositivity, supporting targeted maternal CMV education and evaluation of context‐appropriate ...
Bashir Mohamed Naima, Marie Pascaline Sabine Ishimwe, Theodore Nteziyaremye, Jean de Dieu Rukamba, Musa Kasujja, Theoneste Hakizimana   +5 more
wiley   +1 more source