Results 191 to 200 of about 30,551,261 (265)

Impact of chromatin on HIV-1 latency: a multi-dimensional perspective. [PDF]

Epigenetics Chromatin
Jones JE, Gunderson CE, Wigdahl B, Nonnemacher MR.   +3 more
europepmc   +1 more source

Upstream Stimulatory Factors Regulate HIV-1 Latency and Are Required for Robust T Cell Activation. [PDF]

Viruses, 2023
Horvath RM, Sadowski I.
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Ethnopharmacological exploration and isolation of HIV-1 latency-reversing agents from Sudanese medicinal plants. [PDF]

Front Pharmacol
Elamin KM, Kishimoto N, Kawahara T, Idris Elbashir SM, Yasutake T, Wada M, Hitora Y, Kordofani M, Osman W, Elbashir MI, Misumi S.   +10 more
europepmc   +1 more source

HIV‐1 Vpr Drives a B Cell‐Like Phenotype in Primary CD4+ T Cells

MedComm, Volume 7, Issue 10, October 2026.
During acute HIV‐1 infection, Vpr induces transcriptional and epigenetic remodeling of primary CD4+ T cells, activating a transient B cell‐like program characterized by CD19, MS4A1, CD22, and PAX5 expression and increased chromatin accessibility at lymphocyte differentiation genes.
Peipei Wang, Jieying Li, Wei Wang, Zhuoyue Meng, Huixin Wu, Shumin Du, Kai Deng, Jinfeng Cai   +7 more
wiley   +1 more source

A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency. [PDF]

PLoS Pathog
Ashokkumar M, Hafer TL, Felton A, Archin NM, Margolis DM, Emerman M, Browne EP.   +6 more
europepmc   +1 more source

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

Joint Analysis for Multivariate Longitudinal and Event Time Data With a Change Point Anchored at Interval‐Censored Event Time

Statistics in Medicine, Volume 45, Issue 23-24, October 2026.
ABSTRACT Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor dysfunction, psychiatric disturbances, and cognitive decline. The onset of HD is marked by severe motor impairment, which may be predicted by prior cognitive decline and, in turn, exacerbate cognitive deficits. Clinical data, however, are often
Yue Zhan, Cheng Zheng, Ying Zhang
wiley   +1 more source

Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]

PLoS Pathog
Noorsaeed S, AlBurtamani N, Rokan A, Fassati A.   +3 more
europepmc   +1 more source

The Proteome of Plasma Extracellular Vesicles in Latent and Active Tuberculosis Reveals Phase‐Specific Composition and Immunometabolic Insights

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
Plasma extracellular vesicles (EVs) from individuals with latent (LTB) or active tuberculosis (ATB) exhibit distinct proteomic compositions, reflecting the underlying immunometabolic states of each phase. In LTB, EVs are enriched in proteins associated with tissue remodeling and lipid metabolism, including TGFβ, APOA1, and APOE, which may participate ...
Eliud S.‐Peregrino, Jessica Castañeda‐Casimiro, Luis Vallejo‐Castillo, Mishelle Soria‐Fragoso, Gloria M. Ortega‐Díaz, Karen I. Mondragón‐Lara, Alfonso Méndez‐Tenorio, Rommel Chacón‐Salinas, Blanca E. García‐Pérez, Jeanet Serafín‐López, Carlos Wong‐Baeza, Víctor Hugo Rosales‐García, Alejandro Hernández‐Solis, Isabel Wong‐Baeza   +13 more
wiley   +1 more source