Results 211 to 220 of about 66,330 (250)

The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4⁺ T cells. [PDF]

iScience
Cronin S, de Vries-Egan A, Vahlas Z, Czernikier A, Melucci C, Pereyra Gerber P, O'Neil T, Gloss B, Sharabas M, Turk G, Verollet C, Balboa L, Palmer S, Duette G.   +13 more
europepmc   +1 more source

iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency. [PDF]

Proteome Sci
Yin L, Wang Q, Liu S, Chen J, Zhang Y, Lu L, Lu H, Song Z, Zhang L.   +8 more
europepmc   +1 more source

Novel Triazolopyridine-Based BRD4 Inhibitors as Potent HIV-1 Latency Reversing Agents. [PDF]

ACS Med Chem Lett
Wang YK, Huang XS, Sun H, Ma MD, Yu HP, Hu W, Li ZY, Li Z, Luo RH, Tian RR, Xiao TF, Yang LM, Zheng YT, Li X.   +13 more
europepmc   +1 more source

The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy

, 2022
Prins H, Crespo R, Lungu C, Rao S, Li L, Overmars R, Papageorgiou G, Mueller Y, Hossain T, Kan T, Rijnders B, Bax H, van Gorp E, Nouwen J, de Vries-Sluijs T, Schurink C, de Mendonça Melo M, van Nood E, Colbers A, Burger D, Palstra R, van Kampen J, van de Vijver D, Mesplède T, Katsikis P, Gruters R, Koch B, Verbon A, Mahmoudi T, Rokx C.   +29 more
europepmc   +1 more source

HIV-1 Latency and Latency Reversal: Does Subtype Matter? [PDF]

Viruses, 2019
Cells that are latently infected with HIV-1 preclude an HIV-1 cure, as antiretroviral therapy does not target this latent population. HIV-1 is highly genetically diverse, with over 10 subtypes and numerous recombinant forms circulating worldwide. In spite of this vast diversity, much of our understanding of latency and latency reversal is largely based
Indra Sarabia, Alberto Bosque, Bosque Alberto   +2 more
exaly   +5 more sources

Some of the next articles are maybe not open access.

Related searches:

Mechanisms of HIV-1 latency

AIDS, 1992
This review describes some of the virus-cell relationships that might contribute to the state of latency observed in HIV infection. Viruses use many mechanisms to persist in their host, and the molecular interactions evoked by the virus and the cell on each other can influence the outcome of an infection.
D P, Bednarik, T M, Folks
openaire   +2 more sources

The mTOR Complex Controls HIV Latency [PDF]

Cell Host and Microbe, 2016
A population of CD4 T lymphocytes harboring latent HIV genomes can persist in patients on antiretroviral therapy, posing a barrier to HIV eradication.
Michael Bassik, Erik Verschueren, Warner Greene   +2 more
exaly   +3 more sources

Cellular Latency in HIV-1 Infection

Clinics in Laboratory Medicine, 1994
There are multiple levels of transcriptional regulation that a cell can bring to bear on either native cellular genes or integrated proviral genes. One such level of regulation is inducible sequence-specific transcriptional factors, such as NF-kappa B, which have been extensively investigated with respect to the HIV-1 LTR.
M A, Laughlin, R J, Pomerantz
openaire   +2 more sources

SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency [PDF]

Cell Host and Microbe, 2017
Transcriptional latency of HIV is a last barrier to viral eradication. Chromatin-remodeling complexes and post-translational histone modifications likely play key roles in HIV-1 reactivation, but the underlying mechanisms are incompletely understood.
Steven G Deeks, Warner Greene, Jeffrey Johnson   +2 more
exaly   +3 more sources

Underlying mechanisms of HIV-1 latency

Virus Genes, 2017
Similarly to other retroviruses, HIV-1 integrates its genome into the cellular chromosome. Expression of viral genes from the integrated viral DNA could then be regulated by the host genome. If the infected cell suppresses viral gene expression, the virus will undergo latency.
Bizhan Romani, Elham Allahbakhshi
openaire   +2 more sources