Results 211 to 220 of about 30,551,261 (265)

Entering the Age of Specificity in T Cell Immunity

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley   +1 more source

Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency. [PDF]

PLoS Pathog
Man S, Jansen J, Kroeze S, Geijtenbeek TBH, Kootstra NA.   +4 more
europepmc   +1 more source

Bidirectional Synergistic Interaction Between Influenza Virus and SARS‐CoV‐2 in the Postpandemic Era: A Modeling Study

Influenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Introduction Influenza and COVID‐19 are major respiratory diseases whose co‐circulation dynamics are not fully understood. Surveillance data from the postpandemic period, free from the confounding effects of nonpharmaceutical interventions (NPIs), provide a unique opportunity to study their interactions.
Zhen Qin, Yongyue Wei, Junwen Zhou, Zhicheng Du, Shi Zhao, Zhihang Peng, Yuantao Hao   +6 more
wiley   +1 more source

Croton oligandrus Pierre & Hutch (Euphorbiaceae) Extracts and Isolated Compounds Reverse HIV-1 Latency. [PDF]

J Exp Pharmacol
Emade Nkwelle C, Babiaka SB, Metuge CS, Liang K, Stephens U, Esemu SN, Zuzga DS, Shuda McGuire K, Montaner LJ, Ndip RN, Tietjen I, Ntie-Kang F.   +11 more
europepmc   +1 more source

Validation of Health Belief Model and Theory of Planned Behaviour Constructs for Predicting Malaria Vaccine Acceptance in Ghana: A Partial Least Squares Structural Equation Modelling Approach

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1443-1452, October 2026.
ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo, Michael Snowden, Jamie P. Halsall   +2 more
wiley   +1 more source

Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal. [PDF]

PLoS Pathog
Cisneros WJ, Soliman SHA, Walter M, Simons LM, Cornish D, De Fabritiis S, Halle AW, Kim EY, Wolinsky SM, Lorenzo-Redondo R, Shilatifard A, Hultquist JF.   +11 more
europepmc   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

HIV-1 latency reversal and immune enhancing activity of IL-15 is not influenced by sex hormones. [PDF]

JCI Insight
Holmberg CS, Levinger C, Abongwa M, Ceriani C, Archin NM, Siegel M, Ghosh M, Bosque A.   +7 more
europepmc   +1 more source

GS143, an inhibitor of E3 ligase β-TrCP, reverses HIV-1 latency without activating T cells via unconventional activation of NFκB. [PDF]

PLoS Pathog
Sarkar S, Kobayashi Y, Russnak T, Shen J, Nahass RG, Dougherty JP, Gélinas C.   +6 more
europepmc   +1 more source

ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency. [PDF]

J Virol
Zhou M, Yang T, Yuan M, Li X, Deng J, Wu S, Zhong Z, Lin Y, Zhang W, Xia B, Wu Y, Wang L, Chen T, Liu R, Pan T, Ma X, Li L, Liu B, Zhang H.   +18 more
europepmc   +1 more source