Results 221 to 230 of about 30,551,261 (265)

<i>Ex vivo</i> and <i>in vivo</i> HIV-1 latency reversal by "Mukungulu," a protein kinase C-activating African medicinal plant extract. [PDF]

mBio
Richard K, Yuan Z, Tang H-Y, Goldman AR, Kuthu R, Raphane B, Register ET, Sharma P, Ross BN, Morris J, Williams DE, Cheney C, Wu G, Mounzer K, Laird GM, Zuck P, Andersen RJ, Simonambango S, Andrae-Marobela K, Tietjen I, Montaner LJ.   +20 more
europepmc   +1 more source

Bret/BRAT

Critical Quarterly, Volume 68, Issue 3, Page 103-130, October 2026.
Nicholas Smart
wiley   +1 more source

Pan-caspase inhibitors induce secretion of HIV-1 latency reversal agent lymphotoxin-alpha from cytokine-primed NK cells. [PDF]

Cell Death Discov
Hajikhezri Z, Zygouras I, Sönnerborg A, van Domselaar R.   +3 more
europepmc   +1 more source

Synergistic Activity of Second Mitochondrial-Derived Activator of Caspases Mimetic with Toll-like Receptor 8 Agonist Reverses HIV-1-Latency and Enhances Antiviral Immunity. [PDF]

Int J Mol Sci
Vlaming KE, Jansen J, de Bree GJ, Kootstra NA, Geijtenbeek TBH.   +4 more
europepmc   +1 more source

The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4⁺ T cells. [PDF]

iScience
Cronin S, de Vries-Egan A, Vahlas Z, Czernikier A, Melucci C, Pereyra Gerber P, O'Neil T, Gloss B, Sharabas M, Turk G, Verollet C, Balboa L, Palmer S, Duette G.   +13 more
europepmc   +1 more source

iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency. [PDF]

Proteome Sci
Yin L, Wang Q, Liu S, Chen J, Zhang Y, Lu L, Lu H, Song Z, Zhang L.   +8 more
europepmc   +1 more source

Novel Triazolopyridine-Based BRD4 Inhibitors as Potent HIV-1 Latency Reversing Agents. [PDF]

ACS Med Chem Lett
Wang YK, Huang XS, Sun H, Ma MD, Yu HP, Hu W, Li ZY, Li Z, Luo RH, Tian RR, Xiao TF, Yang LM, Zheng YT, Li X.   +13 more
europepmc   +1 more source

HIV-1 Latency and Latency Reversal: Does Subtype Matter? [PDF]

Viruses, 2019
Cells that are latently infected with HIV-1 preclude an HIV-1 cure, as antiretroviral therapy does not target this latent population. HIV-1 is highly genetically diverse, with over 10 subtypes and numerous recombinant forms circulating worldwide.
Indra Sarabia, Alberto Bosque
exaly   +4 more sources

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Mechanisms of HIV-1 latency

AIDS, 1992
This review describes some of the virus-cell relationships that might contribute to the state of latency observed in HIV infection. Viruses use many mechanisms to persist in their host, and the molecular interactions evoked by the virus and the cell on each other can influence the outcome of an infection.
D P, Bednarik, T M, Folks
openaire   +2 more sources

Cellular Latency in HIV-1 Infection

Clinics in Laboratory Medicine, 1994
There are multiple levels of transcriptional regulation that a cell can bring to bear on either native cellular genes or integrated proviral genes. One such level of regulation is inducible sequence-specific transcriptional factors, such as NF-kappa B, which have been extensively investigated with respect to the HIV-1 LTR.
M A, Laughlin, R J, Pomerantz
openaire   +2 more sources