Results 31 to 40 of about 120,919 (245)

Discontinuation of secondary prophylaxis against Pneumocystis carinii pneumonia in patients with HIV infection who have a response to antiretroviral therapy [PDF]

, 2001
Background: Patients with human immunodeficiency virus (HIV) infection and a history of Pneumocystis carinii pneumonia are at high risk for relapse if they are not given secondary prophylaxis. Whether secondary prophylaxis against P.
H. Furrer, Uberti-Foppa, C., Pradier, C., Bickel, M, Monforte, A D´Arminio, Bickel, M., M. M. E. Schneider, Uberti-Foppa, C, O. Kirk, Furrer, H, Kirk, O., Schneider, M. M., Kirk, O, Lundgren, Jens Dilling, Ledergerber, B., Mocroft, A., Ledergerber, B, Lundgren, J.D., M. Bickel, P. Reiss, Lundgren, J. D., d'Arminio Monforte, A., Pradier, C, A. d'Arminio Monforte, Lederberger, B., Furrer, H., Reiss, P, Schneider, MM, A. Mocroft, for eight European HIV Cohorts, B. Ledergerber, C. Pradier, J. D. Lundgren, Schneider, M.M.E., Mocroft, A, Reiss, P., C. Uberti Foppa   +36 more
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Human Immune System Mice for the Study of Human Immunodeficiency Virus-Type 1 Infection of the Central Nervous System

Frontiers in Immunology, 2018
Immunodeficient mice transplanted with human cell populations or tissues, also known as human immune system (HIS) mice, have emerged as an important and versatile tool for the in vivo study of human immunodeficiency virus-type 1 (HIV-1) pathogenesis ...
Teresa H. Evering, Moriya Tsuji
doaj   +1 more source

The Interplay of HIV and Autophagy in Early Infection

Frontiers in Microbiology, 2021
HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health communities to understand viral infection, to design new drugs or to improve existing ones, as well as to develop advanced therapies and vaccine designs for ...
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Judith Estévez-Herrera, Daniel Márquez-Arce, Cecilia Cabrera, Lucile Espert, Julià Blanco, Julià Blanco, Agustín Valenzuela-Fernández   +8 more
doaj   +1 more source

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing. [PDF]

, 2013
BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize
Grace P McCormack, Crampin, Amelia C., Bansode, Vijay, McCormack, Grace P., Glynn, Judith R., Neil French, Ram K Shrestha, Travers, Simon A, Simon A Travers, French, Neil, Glynn, Judith R, Crampin, Amelia C, Vijay Bansode, Judith R Glynn, Vijay Bansode, Amelia C Crampin, McCormack, Grace P, Travers, Simon A., Shrestha, Ram K., Ngwira, Bagrey, Shrestha, Ram K, Bagrey Ngwira   +21 more
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Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa. [PDF]

PLoS ONE, 2017
Human immunodeficiency virus (HIV)-infected patients are at an increased risk of co-infection with human papilloma virus (HPV), and subsequent malignancies such as oral cancer. To determine the role of HIV-associated immune suppression on HPV persistence
Meghna Verma, Samantha Erwin, Vida Abedi, Raquel Hontecillas, Stefan Hoops, Andrew Leber, Josep Bassaganya-Riera, Stanca M Ciupe   +7 more
doaj   +1 more source

Cellular Determinants of HIV Persistence on Antiretroviral Therapy

, 2018
International audienceThe era of antiretroviral therapy has made HIV-1 infection a manageable chronic disease for those with access to treatment. Despite treatment, virus persists in tissue reservoirs seeded with long-lived infected cells that are ...
Anastassia Mikhailova, Valle-Casuso, Jose Carlos, Jose Carlos Valle-Casuso, Asier Sáez-Cirión, Mikhailova, Anastassia, Saez-Cirion, Asier   +5 more
core   +1 more source

Outcomes for efavirenz versus nevirapine-containing regimens for treatment of HIV-1 infection: a systematic review and meta-analysis. [PDF]

, 2013
INTRODUCTION: There is conflicting evidence and practice regarding the use of the non-nucleoside reverse transcriptase inhibitors (NNRTI) efavirenz (EFV) and nevirapine (NVP) in first-line antiretroviral therapy (ART). METHODS: We systematically reviewed
Pillay, Prinitha, Prinitha Pillay (435496), Pillay Prinitha, Prinitha Pillay, Ford Nathan, Shubber Zara, Shubber, Zara, Ford, Nathan, Rashida A. Ferrand, Ferrand Rashida A., Nathan Ford, Ferrand, Rashida A, Nathan Ford (59436), Zara Shubber (279389), Rashida A. Ferrand (253679), Rashida A Ferrand, Zara Shubber   +16 more
core   +1 more source

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses [PDF]

, 2000
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263-272, KR WIILGLNK).
Anthony D. Kelleher, Jamie Wilson, Wayne Dyer, Sunil Shaunak, Phillips, Rodney, Sullivan, JS, Ian Jones, Workman, C, Rodney E. Phillips, Edward C. Holmes, Kelleher, AD, Christopher Conlon, Rachel L. Allen, John S. Sullivan, Conlon, C, Shaunak, S, Christian Brander, Kara Olson, Goulder, Philip, Allen, RL, Dyer, W, Olson, K, Graham Ogg, Brander, C, Philip Goulder, Mcmichael, Andrew, Ogg, G, Andrew J. McMichael, Long, C, Holmes, EC, Wilson, J, Goulder, P, Cassy Workman, Sarah Rowland-Jones, Rowland-Jones, S, McMichael, AJ, Jones, I, Phillips, RE, Chad Long   +38 more
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Current approaches to assess HIV-1 persistence.

, 2016
The persistence of HIV within long-lived HIV-infected CD4 T cells is the primary obstacle towards HIV eradication and numerous strategies are currently being evaluated to target and kill HIV-infected cells to ultimately find a cure.
Procopio, F.A., Perreau, M., Banga, R.
core   +1 more source

Hybrid Spreading Mechanisms and T Cell Activation Shape the Dynamics of HIV-1 Infection

, 2015
HIV-1 can disseminate between susceptible cells by two mechanisms: cell-free infection following fluid-phase diffusion of virions and by highly-efficient direct cell-to-cell transmission at immune cell contacts.
Pellegrino, P, Groppelli, E, Elisabetta Groppelli (258517), Jolly, C, Ian Williams (208301), Changwang Zhang (716808), Persephone Borrow, Borrow, P, Chain, BM, Benjamin M Chain, Zhou, S, Zhou, Shi, Groppelli, Elisabetta, Persephone Borrow (194557), Ian Williams, Zhang, Changwang, Pellegrino, Pierre, Changwang Zhang, Jolly, Clare, Elisabetta Groppelli, Shi Zhou, Clare Jolly (207781), Pierre Pellegrino (208300), Benjamin M. Chain (154754), Pierre Pellegrino, Williams, Ian, Borrow, Persephone, Shi Zhou (452014), Zhang, C, Chain, Benjamin M., Williams, I, Clare Jolly   +31 more
core   +1 more source