Results 41 to 50 of about 30,666,235 (182)

The Interplay of HIV and Autophagy in Early Infection

Frontiers in Microbiology, 2021
HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health communities to understand viral infection, to design new drugs or to improve existing ones, as well as to develop advanced therapies and vaccine designs for ...
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Judith Estévez-Herrera, Daniel Márquez-Arce, Cecilia Cabrera, Lucile Espert, Julià Blanco, Julià Blanco, Agustín Valenzuela-Fernández   +8 more
doaj   +1 more source

THE PERSISTENCE OF HIV-1 SPREADING IN MSM POPULATION IN CHINA

Journal of Applied Analysis & Computation, 2019
Summary: In this work, we develop and analyze mathematical models for the dynamics about the evolution of HIV/AIDS in men who have sex with men in China. We focus on the analyses of the basic reproduction number \(R_0\) and the persistence of infection.
Li, Yan, Cheng, Jinjin, Lou, Jie
openaire   +2 more sources

Cellular Determinants of HIV Persistence on Antiretroviral Therapy

, 2018
International audienceThe era of antiretroviral therapy has made HIV-1 infection a manageable chronic disease for those with access to treatment. Despite treatment, virus persists in tissue reservoirs seeded with long-lived infected cells that are ...
Anastassia Mikhailova, Valle-Casuso, Jose Carlos, Jose Carlos Valle-Casuso, Asier Sáez-Cirión, Mikhailova, Anastassia, Saez-Cirion, Asier   +5 more
core   +1 more source

Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds [PDF]

, 2015
Transmission of drug-resistant pathogens presents an almost-universal challenge for fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time.
Jürg Böni (36157), Yerly, Sabine, Wan-Lin Yang (709662), Christos Petropoulos (709664), Shilaih, Mohaned, Vincent Aubert (297526), Petropoulos, C., Jürg Böni, Huldrych F. Günthard (173082), Böni, J., Shilaih, M., Wan-Lin Yang, Mohaned Shilaih (709663), Petropoulos, Christos J., Bonhoeffer, S., Roger D Kouyos, Klimkait, Thomas, Sebastian Bonhoeffer, Aubert, Vincent, Kouyos, R.D., Sabine Yerly (82534), Sebastian Bonhoeffer (20372), Swiss HIV Cohort Study (SHCS), Bonhoeffer, Sebastian, Scherrer, Alexandra U, Yerly, S., Yang, W.L., Yerly Ferrillo, Sabine, Swiss, H. I. V. Cohort Study, Hinkley, T., Thomas Klimkait (178911), Günthard, Huldrych F, Kouyos, Roger D., Yang, Wan-Lin, Scherrer, Alexandra U., Alexandra U Scherrer, Mohaned Shilaih, Trevor Hinkley, Aubert, V., Böni, Jürg, Thomas Klimkait, Petropoulos, Christos, Roger D. Kouyos (161982), Alexandra U. Scherrer (214775), Gunthard, Huldrych F., Kouyos, Roger D, Trevor Hinkley (82390), Sabine Yerly, Scherrer, A.U., Günthard, H.F., Klimkait, T., Christos Petropoulos, Vincent Aubert, Bonhoeffer, Sebastian; id_orcid, Hinkley, Trevor, Huldrych F Günthard   +55 more
core   +2 more sources

HIV-1 Proviral Transcription and Latency in the New Era

Viruses, 2020
Three decades of extensive work in the HIV field have revealed key viral and host cell factors controlling proviral transcription. Various models of transcriptional regulation have emerged based on the collective information from in vitro assays and work
Ashutosh Shukla, Nora-Guadalupe P. Ramirez, Iván D’Orso   +2 more
doaj   +1 more source

Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa. [PDF]

PLoS ONE, 2017
Human immunodeficiency virus (HIV)-infected patients are at an increased risk of co-infection with human papilloma virus (HPV), and subsequent malignancies such as oral cancer. To determine the role of HIV-associated immune suppression on HPV persistence
Meghna Verma, Samantha Erwin, Vida Abedi, Raquel Hontecillas, Stefan Hoops, Andrew Leber, Josep Bassaganya-Riera, Stanca M Ciupe   +7 more
doaj   +1 more source

Effect of early antiretroviral therapy during primary HIV-1 infection on cell-associated HIV-1 DNA and plasma HIV-1 RNA

, 2011
BACKGROUND: Early initiation of combination antiretroviral therapy (ART) during primary HIV-1 infection may prevent the establishment of large viral reservoirs, possibly resulting in improved control of plasma viraemia rebound after ART cessation ...
Niederoest, B, Fischer, M., Battegay, Manuel, Günthard, Huldrych F, Fischer, M, Gianella, S., Weber, R, Vernazza, P, Cavassini, M., Gianella, S, Swiss HIV Cohort Study,, Bernasconi, E, Cavassini, M, Battegay, M., Vernazza, P., Joos, B., Rauch, A., Bernasconi, Enos, Weber, R., von Wyl, Viktor, Günthard, Huldrych F., Niederoest, B., Rauch, A, von Wyl, V., Hirschel, Bernard, Rauch, Andri, Joos, B, Günthard, H.F., Joos, Beda, Günthard, H F, Hirschel, B, Gianella, Sara, Niederoest, Barbara, Vernazza, Pietro, Battegay, M, Fischer, Marek, Weber, Rainer, von Wyl, V, Hirschel, B., Cavassini, Matthias, Bernasconi, E.   +40 more
core   +1 more source

Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-up [PDF]

, 2009
OBJECTIVES: Poly-l-lactic acid (PLA) injections modestly increase objectively assessed facial thickness but not facial soft tissue volume (FSTV) over 24 weeks. The durability of this response has not been well defined objectively.
Cooper, D.A., Petoumenos, K, Watson, J., Cooper, D., Carr, A, Baker, D., Carey, D, GD Rogers, Cooper, D. A., Petoumenos, K., Chuah, John, DA Cooper, Chuah, J, Carey, D., Rogers, GD, J Chuah, S Emery, Rogers, G.D., D Carey, K Petoumenos, D Baker, A Carr, Carr, A., Nolan, D., Baker, D, Emery, S, Rogers, Gary, Rogers, G. D., Watson, J, Emery, S., Cooper, DA, Chuah, J., J Watson   +32 more
core   +1 more source

Discontinuation of secondary prophylaxis against Pneumocystis carinii pneumonia in patients with HIV infection who have a response to antiretroviral therapy [PDF]

, 2001
Background: Patients with human immunodeficiency virus (HIV) infection and a history of Pneumocystis carinii pneumonia are at high risk for relapse if they are not given secondary prophylaxis. Whether secondary prophylaxis against P.
H. Furrer, Uberti-Foppa, C., Pradier, C., Bickel, M, Monforte, A D´Arminio, Bickel, M., M. M. E. Schneider, Uberti-Foppa, C, O. Kirk, Furrer, H, Kirk, O., Schneider, M. M., Kirk, O, Lundgren, Jens Dilling, Ledergerber, B., Mocroft, A., Ledergerber, B, Lundgren, J.D., M. Bickel, P. Reiss, Lundgren, J. D., d'Arminio Monforte, A., Pradier, C, A. d'Arminio Monforte, Lederberger, B., Furrer, H., Reiss, P, Schneider, MM, A. Mocroft, for eight European HIV Cohorts, B. Ledergerber, C. Pradier, J. D. Lundgren, Schneider, M.M.E., Mocroft, A, Reiss, P., C. Uberti Foppa   +36 more
core   +2 more sources

Frequent intra-subtype recombination among HIV-1 circulating in Tanzania. [PDF]

, 2013
The study estimated the prevalence of HIV-1 intra-subtype recombinant variants among female bar and hotel workers in Tanzania. While intra-subtype recombination occurs in HIV-1, it is generally underestimated.
Kiwelu, Ireen E, Baca Jeannie, Vladimir Novitsky, Essex, M., Baca, Jeannie, Mary F McLane, Kapiga, Saidi H., Novitsky, Vladimir, Saidi H Kapiga, McLane, Mary F, M Essex, Ireen E Kiwelu, McLane, Mary, Essex, M, Jeannie Baca, Kiwelu Ireen E., Novitsky Vladimir, Manongi, Rachel, Manongi Rachel, Rachel Manongi, Kapiga, Saidi H, Margolin Lauren, Essex M., John Shao, Kiwelu, Ireen E., Noel Sam, Sam Noel, Lauren Margolin, McLane Mary F., Margolin, Lauren, Sam, Noel, Shao John, Kapiga Saidi H., Shao, John   +33 more
core   +1 more source