Results 71 to 80 of about 34,792 (219)
Factors Associated with the Size of HIV DNA Reservoir
Chinese Medical Journal, 2017 Objective: To review the recent literatures related to the factors associated with the size of the HIV reservoir and their clinical significance. Data Sources: Literatures related to the size of HIV DNA was collected from PubMed published from 1999 to ...
Ni-Dan Wang, Tai-Sheng Li
doaj +1 more source
Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain
Alimentary Pharmacology &Therapeutics, EarlyView.Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez +14 more
wiley +1 more source
Brain Pathology, EarlyView.Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
Detectable HIV-1 in semen in individuals with very low blood viral loads
Virology Journal, 2020 Background Several reports indicate that a portion (5–10%) of men living with HIV-1 intermittently shed HIV-1 RNA into seminal plasma while on long term effective antiretroviral therapy (ART).
Samuel Mundia Kariuki +6 more
doaj +1 more source
Structural insights into tyrosine sulfation of CCR5 by human tyrosylprotein sulfotransferase‐1
The FEBS Journal, EarlyView.Structural analysis of human tyrosylprotein sulfotransferase‐1 (hTPST1) bound to a CCR5 N‐terminal peptide reveals how hTPST1 recognizes the Tyr3 sulfation site. Structure‐guided models of additional CCR5 sulfation states and full‐length assemblies provide a framework for understanding CCR5 tyrosine sulfation, a post‐translational modification relevant
Shinnosuke Tanaka +10 more
wiley +1 more source
HIV-1 DNA and the HIV-1 Viral Reservoir
, 2013 HIV-1 infected resting memory CD4+ T cells are major contributors to the HIV-1 viral reservoir, which is established during early infection, maintaining HIV-1 infection for an individual s life. The effect the timing of therapy initiation has on the size and decay of the HIV-1 viral reservoir, the contribution of CD4+ T cell subsets to the viral ...
openaire +2 more sources
HIV Medicine, EarlyView.Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno +13 more
wiley +1 more source
mBio, 2019 The presence of an extremely stable latent reservoir of HIV-1 is the major obstacle to eradication, despite effective antiretroviral therapy (ART). Recent studies have shown that clonal expansion of latently infected cells without viral reactivation is ...
Xiaomin Li +11 more
doaj +1 more source
The forces driving clonal expansion of the HIV-1 latent reservoir
Virology Journal, 2020 Despite antiretroviral therapy (ART) which halts HIV-1 replication and reduces plasma viral load to clinically undetectable levels, viral rebound inevitably occurs once ART is interrupted.
Runxia Liu +2 more
doaj +1 more source
International Journal of Dermatology, EarlyView.Cross‐sectional study among 70 sexual health clinic attendees (70% MSM) in Bucharest combining multisite STI testing with knowledge, attitudes, and practices assessment. Key findings include 35.5% bacterial STI prevalence, essential extragenital testing, and cost barriers to screening uptake.
Andrei Tanasov, George‐Sorin Tiplica
wiley +1 more source