Results 51 to 60 of about 456,511 (292)

1,3,4, Oxadiazole Compound A3 Provides Robust Protection Against PTZ-Induced Neuroinflammation and Oxidative Stress by Regulating Nrf2-Pathway [Retraction]

Journal of Inflammation Research, 2022
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S. J Inflamm Res. 2021;14:7393–7409. The Editor and Publisher of Journal of Inflammation Research wish to retract the published article.
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S   +4 more
doaj  

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster   +13 more
wiley   +1 more source

Regulation of T cell responses by Heme Oxygenase-1 [PDF]

, 2008
Tese de mestrado, Biologia (Biologia Molecular e Genética), 2008, Universidade de Lisboa, Faculdade de CiênciasMultiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system (CNS).
Cortez, Eliane Cristina Monteiro
core  

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells [PDF]

, 2018
Anthocyanins are reported to have cardio-protective effects, although their mechanisms of action remain elusive. We aimed to explore the effects of microbial metabolites common to anthocyanins and other flavonoids on vascular smooth muscle heme oxygenase-
Kay, Colin D, O'Connell, Maria A, Rodriguez-Ramiro, Ildefonso, Warner, Emily F   +3 more
core   +2 more sources

Andrographolide Inhibits Static Mechanical Pressure-Induced Intervertebral Disc Degeneration via the MAPK/Nrf2/HO-1 Pathway

Drug Design, Development and Therapy, 2023
Cunxin Zhang,1,2 Ziang Lu,3 Chaoliang Lyu,2 Shanshan Zhang,4 Dechun Wang1 1Department of Spine Surgery, Qingdao Municipal Hospital, Shandong University, Qingdao, 266061, People’s Republic of China; 2Department of Spine Surgery, Jining No.1 People’s ...
Zhang C, Lu Z, Lyu C, Zhang S, Wang D
doaj  

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt, Anne Maas, Gisela Michel, Amandine Bertrand, Kristen E. T. Thornton, Martine Bellanger, Anna‐Liesa Filbert, Desiree Grabow, Monica Muraca, Katharina Roser, Sara Oberti, Jelena Roganovic, Hanne Cathrine Lie   +12 more
wiley   +1 more source

Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: Nuclear HO-1 promotes vascular endothelial growth factor secretion [PDF]

, 2014
Prostate cancer is the second leading cause of male-cancer related death in the United States. Despite a number of evidence-based studies which strongly suggest an association between cigarette smoking and prostate cancer, the underlying biological ...
BIRRANE, GABRIEL, LI, HUCHUN, SENG, SEYHA, TACHADO, SOUVENIR D., YANG, SUPING   +4 more
core   +1 more source

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes [PDF]

, 2017
Neurodegeneration in Alzheimer’s disease (AD) is extensively studied, and the involvement of astrocytes and other cell types in this process has been described. However, the responses of astrocytes themselves to amyloid peptides ((A; the widely accepted
DJ Selkoe, PD Coleman, L Conforti, C Culmsee, AC LeBlanc, DE Bredesen, C Culmsee, JA Hardy, J Hardy, R Lent, JJ Rodriguez-Arellano, JJ Rodriguez, A Verkhratsky, V Parpura, V Parpura, JA Hewett, GC Petzold, Y Otsu, M Talantova, PR Angelova, D Lim, D Lim, MC Tomasini, D Aguirre-Rueda, J Vina, GT Sutherland, JX Jiang, G Esposito, DH Cho, T Nakamura, TP Misko, N Hettiarachchi, MM Al-Owais, ML Dallas, C Taille, JL Scragg, BJ Murphy, PJ Lee, RT Kinobe, AY Abramov, L Canevari, P Narayan, J Jacobson, AY Abramov, AY Abramov, MH Tran, T Malinski, A Almeida, R Dringen, JP Bolanos, V Thorns, HJ Luth, Z Gu, T Nakamura, J Qu, T Nakamura, H Ischiropoulos, MP Kummer, K Srisook, HM Schipper, HM Schipper, W Song, HM Schipper, K Chen, N Imuta, NT Hettiarachchi, ML Dallas, IF Smith, ML Dallas   +68 more
core   +3 more sources

Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway

Asian Pacific Journal of Tropical Biomedicine
Objective: To assess the hepatoprotective effects of flavone on nicotine-induced liver damage. Methods: Thirty-six rats were allocated into six groups: the control group, the nicotine group, the flavone alone groups (10 and 25 mg/ kg/body weight), and ...
Nora A. Elsayed, Fatma SM Moawed, Esraa SA Ahmed, Ahmed Hammad, Omayma AR Abo-Zaid   +4 more
doaj   +1 more source

The Nrf2-HO-1 system and inflammaging

Frontiers in Immunology
Nrf2 is a master transcriptional regulator of a number of genes involved in the adaptive response to oxidative stress. Among the genes upregulated by Nrf2, heme oxygenase-1 (HO-1) has received significant attention, given that the products of HO-1-induced heme catabolism have well established antioxidant and anti-inflammatory properties.
Sinead A. O’Rourke, Sinead A. O’Rourke, Lianne C. Shanley, Lianne C. Shanley, Aisling Dunne, Aisling Dunne, Aisling Dunne   +6 more
openaire   +3 more sources